A giant esophageal liposarcoma radically resected by the cervical approach: a case report

Furukawa, H; Tanemura, Masahiro; Matsuda, Hiroki; Uotani, Tomofumi; Matsumoto, K.; Okuno, Junko; Higashi, Shigeyoshi; Nonaka, Ryoji; Tsunashima, Ryo; Wakasugi, Masaki; Miyake, Masakazu; Iiboshi, Yasuhiko

doi:10.1007/s12328-021-01550-z

Cited by 4 publications

(8 citation statements)

References 14 publications

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“…As far as we know, there have been 68 reported cases of this tumor so far. However, there have been no reports of esophageal liposarcoma together with esophageal carcinoma [ 5 , 6 ]. Liposarcoma originates from primitive mesenchymal cells, and usually arises from the esophageal submucosa [ 11 , 12 ].…”

Section: Discussionmentioning

confidence: 99%

“…There have been six previous reports of cases of esophageal liposarcoma that were completely resected and removed only through a cervical incisional approach [ 4 , 6 , 19 – 22 ] (Table 1 ). Among them, five cases underwent surgery via a left cervical approach, with the largest tumor being 24 cm in diameter.…”

Section: Discussionmentioning

confidence: 99%

“…Tumor aggressiveness and the prognosis of esophageal liposarcoma are still unclear, but might depend on the histological type, location, and status of surgical margins [ 6 , 23 ]. Ferrari D, et al reported six cases of esophageal liposarcoma recurrences.…”

Section: Discussionmentioning

confidence: 99%

“…Symptomatic cases require surgical resection. To the best of our knowledge, 68 cases of esophageal liposarcoma have been reported since 1983, when the first case was reported [ 4 – 6 ]. However, there have been no reports of esophageal liposarcoma accompanied by esophageal carcinoma.…”

Section: Introductionmentioning

confidence: 99%

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Giant esophageal liposarcoma with squamous cell carcinoma resected via the cervical approach: a case report

et al. 2022

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Background Liposarcoma is one of the most common soft tissue sarcomas, but is extremely rarely found in the esophagus. There have been no reports of esophageal liposarcoma together with superficial carcinoma of the esophagus. Here, we report a patient who underwent complete resection of esophageal liposarcoma with carcinoma via a cervical approach. Case presentation A 66-year-old man was diagnosed with an esophageal tumor 11 years ago, but he left it untreated. He presented to our hospital with progressive dysphagia and appetite loss since the previous year. Esophagogastroduodenoscopy (EGD) showed a large pedunculated submucosal tumor (SMT) originating at the esophageal entrance, extending to the gastroesophageal junction. Additionally, there was a superficial carcinoma on the surface of the SMT, 30 cm from the incisor teeth. Three-dimensional computed tomography (3D-CT) showed a giant elongated intraluminal tumor extending downwards from the cervical esophagus. We diagnosed a giant esophageal polyp accompanied by a superficial carcinoma and performed tumor resection via a cervical approach. The excised specimen consisted of a 23.0 × 8.5 cm polypoid mass. The final diagnosis by histopathological and immunohistochemical examination was well-differentiated liposarcoma and esophageal squamous cell carcinoma. He was discharged on postoperative day 14 with drastic improvement in his swallowing ability. Conclusion We reported an extremely rare case of esophageal liposarcoma together with esophageal squamous cell carcinoma that was successfully resected through a small cervical incision.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Giant esophageal liposarcoma with squamous cell carcinoma resected via the cervical approach: a case report

et al. 2022

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“…They are derived from primitive mesenchymal cells and usually arise from the esophageal submucosa [3]. Since the publication of the first case report in 1983, 76 cases of esophageal liposarcoma have been reported in the English-language medical literature [2][3][4][5][6][7][8][9][10][11][12][13][14][15][16]. The clinical presentation of these tumors is usually with symptoms of dysphagia, dyspnea, or, in some cases, regurgitation of the mass [2].…”

Section: Introductionmentioning

confidence: 99%

Esophageal Liposarcoma: A Case Report and Review of the Literature

Boghani,

Compton,

Postma

et al. 2023

Cureus

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Liposarcomas are extremely rare occurrences in the esophagus. Here, we present an unusual case of esophageal liposarcoma that contributed to a long history of dysphagia before a definitive diagnosis was reached. The case is that of a 61-year-old woman who complained of dysphagia and foreign body sensation in her throat and was found to have a large filling defect within the cervical esophagus on barium esophagogram. She underwent endoscopic resection of the mass and was diagnosed with a five-centimeter long, well-differentiated esophageal liposarcoma, confirmed with fluorescence in situ hybridization for MDM2 gene locus amplification. Subsequent laser ablation of the tumor bed was conducted with no recurrences noted to date. Proper histologic identification, alongside adjunctive cytogenetic and molecular diagnostics, followed by definitive surgical resection and extended follow-up, are emphasized as critical in optimizing outcomes for this disease. A review of the existing English-language medical literature relating to esophageal liposarcoma was performed and summarized.

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Esophageal dedifferentiated liposarcoma resected by the cervical approach: a case report

Omachi,

Kosumi,

Tanizaki

et al. 2024

surg case rep

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Background While liposarcomas tend to mainly occur in the soft tissues of the extremities and retroperitoneum, esophageal liposarcoma is rare. Herein, we report a case of a patient who underwent complete resection of an esophageal dedifferentiated liposarcoma via the cervical approach, leading to the preservation of the esophagus. Case presentation A 69-year-old man underwent an upper gastrointestinal endoscopy, as a result of which a submucosal-like tumor was observed. Upper gastrointestinal imaging showed a 12-cm tumor with a stalk arising from the esophageal entrance, extending to the middle intrathoracic esophagus, with a normal surface mucosa. Endoscopic ultrasound-fine needle aspiration biopsy showed that the nuclei of tumors cells were positive for murine double minute (MDM) and weakly positive for cyclin-dependent kinase 4 (CDK4). We diagnosed the tumor as the esophageal dedifferentiated liposarcoma, and planed tumor resection via the cervical approach. The tumor was successfully resected and the postoperative course was uneventful. Conclusion This case report highlights the use of tumor resection via the cervical approach as a good option for esophageal liposarcoma.

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A giant esophageal liposarcoma radically resected by the cervical approach: a case report

Cited by 4 publications

References 14 publications

Giant esophageal liposarcoma with squamous cell carcinoma resected via the cervical approach: a case report

Giant esophageal liposarcoma with squamous cell carcinoma resected via the cervical approach: a case report

Esophageal Liposarcoma: A Case Report and Review of the Literature

Esophageal dedifferentiated liposarcoma resected by the cervical approach: a case report

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