In this paper, a brand-novel surface plasmon resonance (SPR) biosensor structure built by bimetallic layers (Ag, Al2O3), zinc oxide (ZnO), and black phosphorus (BP) is proposed. The incident light wavelength is 633nm. The angular sensitivity (S), detection accuracy (DA), the figure of merit (FoM), and electric field strength of the proposed construction and other constructions are numerically investigated and compared. To optimize the sensor's performance, the influence of the thickness of each layer on the proposed construction’s performance was simulated. The proposed construction utilizes the large surface-to-volume ratio of ZnO along with the high biomolecule adsorption of BP for sensing performance improvement. It is found that the proposed sensing structure’s highest sensitivity of 400 °/RIU, that's 294.75% higher than the conventional silver-based sensor. This sensing structure might provide ideas for the construction of precision detection suited SPR sensors.