A highly selective “turn-on” fluorescent probe for detecting Cu2+ in two different sensing mechanisms

A highly selective aggregation‐induced emission fluorogen for sensitive detection of Al3+ in living cells

“…In this study, we prepared a fluorescent probe based on coumarin and furan‐2‐carbohydrazide using the Schiff base reaction (Scheme ). Coumarin is an excellent fluorophore with high fluorescence quantum yield, good optical stability, low toxicity and ease of preparation; furan‐2‐carbohydrazide is well provided with coordination sites. This probe showed favourable specificity and sensitivity, and a capability for fluorescence imaging in living cells.…”

A novel hydrophilic fluorescent probe for Cu2+ detection and imaging in HeLa cells

“…[28][29][30][31] Many recent reports describe excellent uorescent sensors for detecting Cu 2+ . [32][33][34][35][36][37][38] However, there are many unavoidable drawbacks for the probes that have been reported so far, such as weak hydrophilia, tedious synthetic steps, stringent applied conditions, and the likelihood of interference from Hg 2+ , Al 3+ , or Zn 2+ . Therefore, more research is required to develop uorescent probes with strong hydrophilia, good biocompatibility, low toxicity, high anti-interference ability, and easy preparation.…”

A dual‐function chemosensor based on coumarin for fluorescent turn‐on recognition of Hg2+ and colorimetric detection of Cu2+ in aqueous media

“…However, most of them faced some thorny problems, such as unable to identify by the naked eye, too complicated synthesis process, difficultly in purification, and cannot be used in water environment monitoring. Meanwhile, the majority of chemosensors are single‐ion selective while multi‐ion responsive systems are reported in few studies . The single chemosensor for dual targets has aroused wide concern, which can distinguish more than one target simultaneously with multiple signal channels effectively shortening the overall analytical processing time and potentially reducing the cost .…”