A Highly Sensitive Ascorbic Acid Sensor Based on Graphene Oxide/CdTe Quantum Dots-Modified Glassy Carbon Electrode

Küçükkolbaşı, Semahat; Erdoğan, Zehra Özden; Baslak, Canan; Sogut, D.; Kuş, Mahmut

doi:10.1134/s1023193519010051

Cited by 21 publications

(6 citation statements)

References 36 publications

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“…The relative standard deviation was measured at two levels of concentration mass of AA, i.e., 45 μg L −1 and 158 μg L −1 and calculated to be 4.2 % and 3.8%, respectively, values indicating the good reproducibility of the proposed assay. The linear detection region of AA in the present study is in several cases better than that determined by the corresponding electrochemical techniques in the literature [ 11 , 12 , 13 , 14 , 15 , 16 , 17 , 18 , 19 , 20 , 21 , 22 , 23 , 24 , 25 , 26 , 27 , 28 , 29 , 30 , 31 , 32 , 33 , 34 , 35 , 36 , 37 , 38 , 39 , 40 , 41 , 45 ] On the other hand, the detection limit of the current analytical AA detection methodology is better compared to the majority of those determined with the other corresponding electrochemical techniques available in the literature, with the exception that it is in the same magnitude of Zhao et 2019 [ 20 ], Kaçar and Erden 2020 [ 2 ], Broncová et al 2021 [ 34 ], Pekin et al [ 45 ], as it can be seen from Table 1 .…”

Section: Analytical Performance Of the Proposed Assaymentioning

confidence: 49%

“…Meanwhile, for the electrochemical determination of AA, electrodes with modified surfaces have been widely used, overlapping the fulling effect due to oxidation that may occur on the conventional electrode surfaces [ 6 ]. Carbon paste (CPE) [ 12 , 19 ] and glassy carbon (GCE) [ 20 , 21 , 22 , 23 , 24 , 25 , 26 , 27 , 28 , 29 , 30 , 31 , 32 , 33 ] modified electrodes are the most commonly used for AA analysis in the available literature. Moreover, Pt modified electrodes with 3,4-diaminobenzoic acid and neutral red [ 34 ] or screen-printed electrodes (SPE) [ 35 , 36 , 37 ].…”

Section: Introductionmentioning

confidence: 99%

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Selective Voltammetric Detection of Ascorbic Acid from Rosa Canina on a Modified Graphene Oxide Paste Electrode by a Manganese(II) Complex

2021

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Voltammetric techniques have been considered as an important analytical tool applied to the determination of trace concentrations of many biological molecules including ascorbic acid. In this paper, ascorbic acid was detected by square wave voltammetry, using graphene oxide paste as a working electrode, modified by a film of a manganese(II) complex compound. Various factors, such as the effect of pH, affecting the response characteristics of the modified electrode were investigated. The relationship between the peak height and ascorbic acid concentration within the modified working electrode was investigated, using the calibration graph. The equation of the calibration graph was found to be: I = 0.0550γac + 0.155 with R2 = 0.9998, where I is the SWV current and γac is the mass concentration of ascorbic acid. The LOD and LOQ of the proposed method were determined to be 1.288 μg/L and 3.903 μg/L, respectively. Several compounds, such as riboflavin, biotin, and ions, such as Fe and Cu, were tested and it seemed that they did not interfere with the analytic signal. The proposed procedure was successfully applied in the determination of ascorbic acid in Rosa canina hips.

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Section: Analytical Performance Of the Proposed Assaymentioning

confidence: 49%

Section: Introductionmentioning

confidence: 99%

Selective Voltammetric Detection of Ascorbic Acid from Rosa Canina on a Modified Graphene Oxide Paste Electrode by a Manganese(II) Complex

2021

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“…In this case, the interference was substantial. This is not surprising since ascorbic acid is capable of oxidation at a low applied potential [65]. This should not be a problem for the measurement of glucose in many beverages or, particularly, in plasma, where the concentration of glucose is more than two orders of magnitude higher than that of ascorbic acid [66,67].…”

Section: Reproducibility Repeatability and Interference Studiesmentioning

confidence: 99%

Enhancing Glucose Biosensing with Graphene Oxide and Ferrocene-Modified Linear Poly(ethylenimine)

Monkrathok,

Janphuang,

Suphachiaraphan

et al. 2024

Biosensors

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We designed and optimized a glucose biosensor system based on a screen-printed electrode modified with the NAD-GDH enzyme. To enhance the electroactive surface area and improve the electron transfer efficiency, we introduced graphene oxide (GO) and ferrocene-modified linear poly(ethylenimine) (LPEI-Fc) onto the biosensor surface. This strategic modification exploits the electrostatic interaction between graphene oxide, which possesses a negative charge, and LPEI-Fc, which is positively charged. This interaction results in increased catalytic current during glucose oxidation and helps improve the overall glucose detection sensitivity by amperometry. We integrated the developed glucose sensor into a flow injection (FI) system. This integration facilitates a swift and reproducible detection of glucose, and it also mitigates the risk of contamination during the analyses. The incorporation of an FI system improves the efficiency of the biosensor, ensuring precise and reliable results in a short time. The proposed sensor was operated at a constant applied potential of 0.35 V. After optimizing the system, a linear calibration curve was obtained for the concentration range of 1.0–40 mM (R2 = 0.986). The FI system was successfully applied to determine the glucose content of a commercial sports drink.

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“…A more sensitive, inexpensive and reliable sensor was prepared by Kucukkolbasi et al [ 211 ] based on a GO/CdTeQDs/GC electrode prepared via hydrothermal synthesis of the CdTeQDs followed by drop casting. CV and EIS experiments revealed that the modified electrode showed better performance than the bare GC one.…”

Section: Graphene-based Sensors For Bioactive Compoundsmentioning

confidence: 99%

Graphene-Based Sensors for the Detection of Bioactive Compounds: A Review

Sainz-Urruela

Vera

Andrés

et al. 2021

IJMS

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Over the last years, different nanomaterials have been investigated to design highly selective and sensitive sensors, reaching nano/picomolar concentrations of biomolecules, which is crucial for medical sciences and the healthcare industry in order to assess physiological and metabolic parameters. The discovery of graphene (G) has unexpectedly impulsed research on developing cost-effective electrode materials owed to its unique physical and chemical properties, including high specific surface area, elevated carrier mobility, exceptional electrical and thermal conductivity, strong stiffness and strength combined with flexibility and optical transparency. G and its derivatives, including graphene oxide (GO) and reduced graphene oxide (rGO), are becoming an important class of nanomaterials in the area of optical and electrochemical sensors. The presence of oxygenated functional groups makes GO nanosheets amphiphilic, facilitating chemical functionalization. G-based nanomaterials can be easily combined with different types of inorganic nanoparticles, including metals and metal oxides, quantum dots, organic polymers, and biomolecules, to yield a wide range of nanocomposites with enhanced sensitivity for sensor applications. This review provides an overview of recent research on G-based nanocomposites for the detection of bioactive compounds, providing insights on the unique advantages offered by G and its derivatives. Their synthesis process, functionalization routes, and main properties are summarized, and the main challenges are also discussed. The antioxidants selected for this review are melatonin, gallic acid, tannic acid, resveratrol, oleuropein, hydroxytyrosol, tocopherol, ascorbic acid, and curcumin. They were chosen owed to their beneficial properties for human health, including antibiotic, antiviral, cardiovascular protector, anticancer, anti-inflammatory, cytoprotective, neuroprotective, antiageing, antidegenerative, and antiallergic capacity. The sensitivity and selectivity of G-based electrochemical and fluorescent sensors are also examined. Finally, the future outlook for the development of G-based sensors for this type of biocompounds is outlined.

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A Highly Sensitive Ascorbic Acid Sensor Based on Graphene Oxide/CdTe Quantum Dots-Modified Glassy Carbon Electrode

Cited by 21 publications

References 36 publications

Selective Voltammetric Detection of Ascorbic Acid from Rosa Canina on a Modified Graphene Oxide Paste Electrode by a Manganese(II) Complex

Selective Voltammetric Detection of Ascorbic Acid from Rosa Canina on a Modified Graphene Oxide Paste Electrode by a Manganese(II) Complex

Enhancing Glucose Biosensing with Graphene Oxide and Ferrocene-Modified Linear Poly(ethylenimine)

Graphene-Based Sensors for the Detection of Bioactive Compounds: A Review

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