This paper presents the effect of received signal strength on IMU/GNSS sensor data transmission for autonomous vehicle navigation. A pixhawk 2.1 flight controller is used to build the navigation system. Straight lines with back-andforth routes were tested using two types of SiK telemetry: Holybro and RFD. The results of the tests show that when the RSSI value falls close to the receiver's sensitivity value, the readings of the gyro sensor data, accelerometer, magnetometer, and GNSS compass data are disturbed. When the RSSI signal collides with noise, the radio telemetry link is lost, affecting the accuracy of speed data and the orientation of autonomous vehicles. According to Cisco's conversion table, the highest RSSI on Holybro telemetry is -48 dBm, and the lowest is -103 dBm, with a receiver sensitivity of -117 and data reading at a distance of about 427 meters. While the highest RSSI value on RFD telemetry is -17 dBm and the lowest is -113 dBm, even the lowest value is above the receiver's sensitivity limit of -121 dBm with data readings at a distance of approximately 749.4 meters. RFD outperforms Holybro in terms of RSSI and sensitivity at low data rates. When reading distance data to reference distance data using Google Earth and ArcGIS, RFD telemetry has a higher accuracy, with an average accuracy of 98.8%.