A Multidimensional Sensing Device for the Discrimination of Proteins Based on Manganese‐Doped ZnS Quantum Dots

Wu, Peng; Miao, Ling-Ni; Wang, Hefang; Shao, Xueguang; Yan, Xiu‐Ping

doi:10.1002/anie.201101882

Cited by 216 publications

(137 citation statements)

References 57 publications

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“…These new spectral properties are quite different from those of pure PEI and most of the MnÀZnS nanoparticles. [13,14] Pure PEI did not show any absorption in the range of l = 250-700 nm and only exhibited one very weak emission for band G (Figure 1 B), whereas most MnÀ ZnS nanoparticles only displayed the band-edge absorption of ZnS at about l = 300 nm, and simultaneously excited PL bands at about l = 450 and 590 nm. [8, 14f] The new absorption at l % 365 nm and the individually excited PL band G of PEI/MnÀ ZnS nanocomposites can be ascribed to the CT complex of PEI and Zn/Mn.…”

Section: Synthesis and Characterization Of Pei/mnàzns Nanocompositesmentioning

confidence: 99%

“…A 1 ), which was incorporated into the ZnS host lattice (Figure 1 B). [13,14] Owing to the presence of PEI with abundant amino groups, the PEI/MnÀZnS nanocomposite was highly water soluble and exhibited good acidic stability, [12a,b] even at pH 3.0-5.0 ( Figure S3 in the Supporting Information). In addition, the PL properties of the PEI/ MnÀZnS nanocomposite could be adjusted by controlling the feed ratio of PEI/Zn (Figure 2 A) as a result of the super capabilities of PEI to coordinate with metals.…”

Section: Synthesis and Characterization Of Pei/mnàzns Nanocompositesmentioning

confidence: 99%

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Polyethyleneimine/Manganese‐Doped ZnS Nanocomposites: A Multifunctional Probe for Two‐Color Imaging and Three‐Dimensional Sensing

Sang

Wang

2013

ChemPlusChem

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We present herein a new single probe, polyethyleneimine (PEI)/MnZnS nanocomposite, for two‐color imaging and three‐dimensional sensing. The PEI/MnZnS nanocomposite possesses unique, individually excited, two‐color, photoluminescence (PL) emissions at λ=495 and 585 nm; this allows two‐color imaging of the same space just by changing the excitation wavelength in situ. Moreover, the two PL bands of the nanocomposite are orthogonal, which allows the discrimination of eight proteins just by recording the three‐channel optical signals of the single probe. The two PL bands of the PEI/MnZnS composite are capable of distinguishing eight proteins at 0.5 μM, whereas the three‐channel signals (two PL bands and light scattering) can discriminate these proteins at no less than 0.25 μM.

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Section: Synthesis and Characterization Of Pei/mnàzns Nanocompositesmentioning

confidence: 99%

Section: Synthesis and Characterization Of Pei/mnàzns Nanocompositesmentioning

confidence: 99%

Polyethyleneimine/Manganese‐Doped ZnS Nanocomposites: A Multifunctional Probe for Two‐Color Imaging and Three‐Dimensional Sensing

Sang

Wang

2013

ChemPlusChem

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“…Liu et al [88] established a dual-channel sensor by the changes of conductivity and emission of CL during catalytic reaction of VOCs on nano-SnO 2 . Wu et al [89] simultaneously utilized the optical properties of Mn-doped ZnS QDs to develop a triple-channel sensor for the discrimination of eight proteins in a "lab-on-a-nanoparticle" mode. The multidimensional sensor is even able to identify the target protein in complex sample matrix, showing good application prospects.…”

Section: Sensorsmentioning

confidence: 99%

Exploration of nano-surface chemistry for spectral analysis

Liu

Lü

et al. 2013

Chin. Sci. Bull.

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The applications of nano-surface chemistry in the field of spectral analysis have attracted growing interest in recent years. In this article, we reviewed the applications of nanomaterials-based chemical reactions for spectral analysis, including the development in plasma-catalysis, surface-enhanced spectroscopy, separation and preconcentration, chemical vapor generation, labeling and signal amplification. Introduction of nano-surface chemistry to spectral analysis not only improves the sensitivity and selectivity, broadens the application range of spectral analysis, but also affords analytical community special characterization tools.surface chemistry, nanomaterial, plasma, separation, chemical vapor generation, opticle gas sensors, atomic spectrometry Citation:Li C H, Liu R, Lü Y, et al. Exploration of nano-surface chemistry for spectral analysis.

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“…[10]. Some authors, for instance, have shown their potential biological applications in fluorescent biolabeling [14] and biosensing [15,16]. In this work, we present optimized ZnSe nanoparticles obtained as result of a chemometric assay applied to a simple colloidal route for the synthesis of water-dispersed Mndoped ZnSe QDs aiming at high intensity d-d emission for biolabeling purposes.…”

Section: Introductionmentioning

confidence: 98%

ZnSe:Mn aqueous colloidal quantum dots for optical and biomedical applications

Silva

Moura

Filho

et al. 2016

Phys. Status Solidi C

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In this study, we present the optimization of the optical properties of Mn2+ doped ZnSe QDs (also referred to as d‐dots) coated with thioglycolic acid in aqueous medium. The nanoparticles were characterized by ionic coupled plasma, electron paramagnetic resonance, transmission electron microscopy and X‐ray diffractometry. By applying a controlled dose of UV irradiation, we obtained efficient orange emitting d‐dots (4T1→ 6A1 transition centered at 580 nm). The results point out to a doping fraction in the nanoparticles smaller than 1% (0.89%), and that the Mn2+ ions are preferentially located close to the particle's surface. The UV photoactivation procedure has a definite influence on the emission intensity and on the colloidal stability of the particles. Photoactivated Mn2+ d‐dots were conjugated to Concanavalin A and labeled specifically Candida albicans yeast cells, by targeting carbohydrate residues depicting the successful use of these QDs as fluorescent probes. (© 2016 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)

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A Multidimensional Sensing Device for the Discrimination of Proteins Based on Manganese‐Doped ZnS Quantum Dots

Abstract: Lab-on-a-nanoparticle: the triple-channel optical properties of Mn-doped ZnS quantum dots (fluorescence, phosphorescence, and light scattering) are explored to develop a multidimensional sensing device for the discrimination of proteins in a lab-on-a-nanoparticle approach.

Cited by 216 publications

References 57 publications

Polyethyleneimine/Manganese‐Doped ZnS Nanocomposites: A Multifunctional Probe for Two‐Color Imaging and Three‐Dimensional Sensing

Polyethyleneimine/Manganese‐Doped ZnS Nanocomposites: A Multifunctional Probe for Two‐Color Imaging and Three‐Dimensional Sensing

Exploration of nano-surface chemistry for spectral analysis

ZnSe:Mn aqueous colloidal quantum dots for optical and biomedical applications

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