A nested case–control study on dietary fat consumption and the risk for gallstone disease

Compagnucci, Agustina Bertola; Perroud, Herman A.; Batallés, Stella Maris; Villavicencio, R; A, Brasca; Berli, D.; Pezzotto, Stella Maris

doi:10.1111/jhn.12332

Cited by 20 publications

(15 citation statements)

References 33 publications

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“…There has been no study that differentiated cholesterol and pigment gallstones in relation to diet. Previous studies reported that the risk of gallstone was positively associated with intake of meat [ 6 ], fat, and saturated fat in Europeans [ 7 , 8 , 13 , 19 ]. Meat, a major source of fat and saturated fat, was positively associated with risk of gallstones, while unsaturated fatty acid was negatively associated [ 7 ].…”

Section: Discussionmentioning

confidence: 99%

Association between diet and gallstones of cholesterol and pigment among patients with cholecystectomy: a case-control study in Korea

Park

Kim

Lee

et al. 2017

J Health Popul Nutr

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BackgroundThe prevalence of cholesterol gallstones is high in Western populations, while pigment gallstones are common in Asian populations. Dietary factors are suggested to be associated with gallstone risk, but their relationship with gallstone type has not been evaluated. This study investigated the association between diet and risk of cholesterol gallstone or pigment gallstone in a Korean population whose dietary pattern and type of gallstone were changed during the last 30 years.MethodsPatients with cholesterol (n = 40) and pigment (n = 59) gallstones were recruited after laparoscopic cholecystectomy and were compared with those of age- and sex-matched controls without gallstones (n = 99). Dietary intakes were assessed by trained dietitians using a semi-quantitative food frequency questionnaire. Multinomial logistic regression analysis was performed to calculate odds ratios and 95% confidence intervals to examine the associations between diet and risk for type of gallstones adjusted by potential confounders.ResultsPatients with cholesterol gallstone consumed more lipid, animal lipid, beef, pork, and fried food than those with pigment gallstones and control, while patients with pigment gallstone consumed more carbohydrate and noodles than patients with cholesterol gallstone and control. In multinomial logistic regression analysis using control as reference group, dietary pattern with high consumption of beef, pork, and fried food was associated with risk of cholesterol gallstones, while there was no association between the risk of pigment gallstone and dietary pattern. In addition, control consumed more alcohol than patients with cholesterol and pigment gallstones.ConclusionsThe present study suggested consumption of fat from meat and fried foods increased the risk of cholesterol gallstone, and intake of carbohydrate from noodles increased the risk of pigment gallstone.Electronic supplementary materialThe online version of this article (10.1186/s41043-017-0116-y) contains supplementary material, which is available to authorized users.

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Section: Discussionmentioning

confidence: 99%

Association between diet and gallstones of cholesterol and pigment among patients with cholecystectomy: a case-control study in Korea

Park

Kim

Lee

et al. 2017

J Health Popul Nutr

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“…GSD is multifactorial in origin, including genetic and dietary factors [5]. Many risk factors are associated, such as weight, age, dyslipidemia, chronic liver disease, gender, and parity [6].…”

Section: Introductionmentioning

confidence: 99%

Association of Body Mass Index and Diet with Symptomatic Gall Stone Disease: A Case-Control Study

Kiani

Farooqui

Khan

et al. 2020

Cureus

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Background: Gall stone disease (GSD) is one of the commonest gastrointestinal disorders. Causative factors can be non-modifiable as genetics and modifiable like dietary habits. High-fat diet and high BMI are well known contributing factors world-over. Local and regional data is deficient about these factors. Moreover, Indo-Pakistani dietary patterns are very different from the western population. This study was conducted to see the association of high BMI and diet with GSD in our population.Materials and Methods: This case-control study was conducted in Shifa International Hospital, Islamabad, from 2012 to 2017. We included all female patients above 25 years of age with symptomatic gall stones on ultrasonography as cases and all females above 25 years of age with no gall stones on ultrasonography (done for any reason) as controls. The patients with gall stones having some other clear predisposing cause for gallstone formation, e.g., stoma, sudden weight loss, etc. were excluded. BMI, demographic details, dietary habits, and clinical profile of cases and controls were recorded. Data were analyzed by SPSS v 21. p-values were calculated.Results: A total of 396 patients were included in this study, with 103 cases and 293 controls. The mean BMI of GSD cases was 27.576±5.753, while controls had a mean BMI of 25.638±7.008 (p=0.08). About 26.4% of cases had an average fat consumption greater than 100g/day as compared to 11.9% controls (p=0.035). The average red meat intake per week was 222g among cases while 210g among controls (p=0.001). The average intake of fried food per week was 270g among controls and 250g among cases (p=0.012). The average intake of bakery items per week was 240g among cases and 210g among controls (p=0.038). Conclusion:Gall stone disease is significantly related to high BMI and high dietary fat and meat intake in our population.

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“…El consumo de comida chatarra en nuestra investigación resultó con significación estadística; se evidenció que los pacientes que no tenían cálculos en la vesícula tenían un consumo de comida chatarra menor de 2 días a la semana; a diferencia de los que sí tenían colelitiasis (diagnosticados por ecografía abdominal) donde consumían por lo menos 2 veces a la semana comida chatarra; esto se apoya con lo encontrado por los estudios de Compagnucci y Park quienes demostraron que el consumo de grasas saturadas y monoinsaturadas incrementaban el riesgo de cálculos en la vesícula 7,15 , adicionalmente a esto, Lander encontró que el consumo de proteínas vegetales disminuía el riesgo de padecer cálculos de la vesícula 16 . En Chile, del Pozo, en un estudio experimental en ratones concluye que la ingestión de una dieta alta en grasas, y en mayor predominio grasas saturadas, podría contribuir a la formación de cálculos de colesterol en la VB, principalmente, en un estadio temprano 17 .…”

Section: Discussionunclassified

Estado nutricional, actividad física y consumo de comida chatarra asociados a colelitiasis en huánuco. Estudio de casos y controles

et al. 2020

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Objetivos: Determinar la asociación entre el consumo de comida chatarra, actividad física y estado nutricional en pacientes con colelitiasis a la ecografía (casos), comparados con controles aparentemente sanos sin colelitiasis a la ecografía, en consulta externa del Hospital EsSalud II Huánuco. Materiales y métodos: Estudio de casos y controles. Se incluyeron 107 casos y 107 controles. El consumo de comida “chatarra” se valoró con la encuesta validada por RSEQ (Red deportiva estudiantil de Québec), la frecuencia del consumo (días por semana); la actividad física por el cuestionario IPAQ (Cuestionario Internacional de Actividad Física) y el estado nutricional mediante el Índice de masa corporal. En el análisis estadístico se empleó el Chi cuadrado, U de Mann Whitney y Odds Ratio (p<0,05).Resultados: La edad y la procedencia no fueron significativos. El consumo de comida “chatarra” estuvo asociado a la colecistitis (OR 10,30; IC 95% 5,48-19,37). La actividad física moderada-vigorosa (> 600 MET) promovió el diagnóstico de colecistitis (OR 8,38; IC 95% 4,54-15,48) y el estado nutricional (sobrepeso o mayor), en forma significativa, promovía la colecistitis (OR 11,38; IC 95% 6,01-21,55). Ser femenino estuvo asociado al desarrollo de colecistitis (OR 2,06; IC 95% 1,19-3,55).Conclusión: el consumo de comida “chatarra”, la actividad física moderada-vigorosa (> 600 MET), el estado nutricional (sobrepeso o mayor) y el género (femenino) fueron asociados al desarrollo de colelitiasis diagnosticados mediante ecografía.

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A nested case–control study on dietary fat consumption and the risk for gallstone disease

Abstract: According to our results, total fat, saturated and monounsaturated fatty acids high intakes are associated with increased GD risk.

Cited by 20 publications

References 33 publications

Association between diet and gallstones of cholesterol and pigment among patients with cholecystectomy: a case-control study in Korea

Association between diet and gallstones of cholesterol and pigment among patients with cholecystectomy: a case-control study in Korea

Association of Body Mass Index and Diet with Symptomatic Gall Stone Disease: A Case-Control Study

Estado nutricional, actividad física y consumo de comida chatarra asociados a colelitiasis en huánuco. Estudio de casos y controles

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