A new 675-nm laser device in the treatment of acne scars: an observational study

Cannarozzo, Giovanni; Silvestri, Martina; Tamburi, Federica; Sicilia, Claudia; Duca, Ester Del; Scali, Elisabetta; Bennardo, Luigi; Nisticò, Steven Paul

doi:10.1007/s10103-020-03063-6

Cited by 38 publications

(32 citation statements)

References 6 publications

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“…Using a wavelength of 635 nm at 3 J/cm 2 at a distance of 3 cm from the sample, Huang et al found that by activating the Copper-glycyl-L-histidyl-L-lysin complex (Cu-GHK), red light increases the main secretion fibroblast growth factor, i.e., basic fibroblast growth factor (bFGF), and the production of procolagen 1 carboxyterminal propeptide (P1CP 9) which directly accelerates the wound healing process through its anti-inflammatory effects [46]. Cannarozzo et al confirmed that 675 nm wavelength is useful to treatment of scars [47]. A statistically significant increase in fibroblast proliferation with red light was noted by most researchers at an energy density under 15 J/cm 2 .…”

Section: Discussionmentioning

confidence: 99%

Assessment of Human Gingival Fibroblast Proliferation after Laser Stimulation In Vitro Using Different Laser Types and Wavelengths (1064, 980, 635, 450, and 405 nm)—Preliminary Report

Sterczała

Grzech‐Leśniak

Michel

et al. 2021

JPM

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Purpose: to assess the effect of photobiomodulation (PBM) on human gingival fibroblast proliferation. Methods: The study was conducted using the primary cell cultures of human fibroblasts collected from systemically healthy donors. Three different laser types, Nd:YAG (1064 nm), infrared diode laser (980 nm), and prototype led laser emitting 405, 450, and 635 nm were used to irradiate the fibroblasts. Due to the patented structure of that laser, it was possible to irradiate fibroblasts with a beam combining two or three wavelengths. The energy density was 3 J/cm2, 25 J/cm2, 64 J/cm2. The viability and proliferation of cells were determined using the (Thiazolyl Blue Tetrazolium Blue) (MTT) test conducted 24, 48, and 72 h after laser irradiation. Results: The highest percentage of mitochondrial activity (MA = 122.1%) was observed in the group irradiated with the 635 nm laser, with an energy density of 64 J/cm2 after 48 h. The lowest percentage of MA (94.0%) was observed in the group simultaneously irradiated with three wavelengths (405 + 450 + 635 nm). The use of the 405 nm laser at 25 J/cm2 gave similar results to the 635 nm laser. Conclusions: The application of the 635 nm and 405 nm irradiation caused a statistically significant increase in the proliferation of gingival fibroblasts.

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Section: Discussionmentioning

confidence: 99%

Assessment of Human Gingival Fibroblast Proliferation after Laser Stimulation In Vitro Using Different Laser Types and Wavelengths (1064, 980, 635, 450, and 405 nm)—Preliminary Report

Sterczała

Grzech‐Leśniak

Michel

et al. 2021

JPM

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“…Scars exposed after tattoo removal may then be treated as all other marks are: with a pulsed dye laser device or with some of the new lasers that target connective tissue. The results, however, may not be always cosmetically acceptable [23,24] (de las alas, cannarozzo). Q-Switched lasers have been on the market for numerous years; the technology and pulse duration have been modified during this time, and the picosecond pulsed laser is considered the gold standard in tattoo removal [25,26].…”

Section: Discussionmentioning

confidence: 99%

Picosecond Q-Switched 1064/532 nm Laser in Tattoo Removal: Our Single Center Experience

et al. 2021

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Background: Tattoo removal is becoming increasingly popular, and Q-switched lasers represent the gold standard in the treatment of this condition. In this study, we report our experience with a new Q-switched picosecond laser device, evaluating its effectiveness and safety. Methods: A total of 34 patients asking for tattoo removal were consecutively enrolled in this open study. The clinicians decided on operating settings based on the Fitzpatrick phototype, the type of tattoo, and the tattoo location. A maximum of seven sessions, with a minimum interval of eight weeks between each session, were performed. At the six month follow-up visit following the last treatment session, patient satisfaction was assessed using a visual analogue scale and two dermatologists evaluated the aesthetic outcome based on pictures taken before and after treatment. Results: A total of 34 patients were included and analyzed: 17 females (50%) and 17 males (50%). The mean patient age was 43.6 ± 11 years. Participants’ Fitzpatrick skin type ranged from II to IV. The mean number of treatment sessions performed was 3.3 ± 2.0 per patient. Over 40% of patients showed complete removal of the tattoo, with most of the patients indicating satisfaction with the treatment. Conclusions: The Q-switched 1064/532 nm laser may be considered the gold standard treatment for tattoo removal. Picosecond pulses seem to guarantee fewer sessions and excellent results when compared to other laser systems in tattoo removal.

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“…Non-ablative lasers stimulate dermal fibroblasts to produce new collagen. Nd-YAG, diode and recently a new 675-nm Red Touch laser are various types of non-ablative lasers used to treat acne scars [7].…”

Section: Introductionmentioning

confidence: 99%

Efficacy and Safety of 25% Trichloroacetic Acid Peel Versus 30% Salicylic Acid Peel in Mild-to-Moderate Acne Vulgaris: A Comparative Study

Dayal

Singh

Sahu

2021

Dermatol Pract Concept

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Background: Both salicylic acid (SA) and trichloroacetic acid (TCA) have proven efficacy with goodsafety profiles in the treatment of acne vulgaris. Objectives: This study compared the clinical efficacy and safety of 25% TCA and 30% SA peels in thetreatment of mild and moderate acne vulgaris. Methods: Patients with mild or moderate acne vulgaris were randomized into 2 groups of 25 personseach, and treated with either the TCA peel or the SA peel at 2-week intervals for 12 weeks. Evaluationof active acne was done by individual lesion counts (comedones, papules and pustules) and calculationof the Michaelsson acne score (MAS). Results: Both peels led to significant decrease in individual lesion counts and MAS compared to baselinevalues, without significant differences between the treatment groups. Thus, the peels had equivalentefficacy against acne vulgaris. The TCA peel was better in treating non-inflammatory lesions,while the SA peel was better for inflammatory lesions, but the differences were not significant. Noserious adverse effects were recorded, but more patients in the TCA peel group experienced burningand stinging sensations. Conclusion: The efficacy of 25% TCA is comparable to that of 30% SA in mild-to-moderate acnevulgaris, but safety and tolerability were better with the SA peel than TCA peel.

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A new 675-nm laser device in the treatment of acne scars: an observational study

Cited by 38 publications

References 6 publications

Assessment of Human Gingival Fibroblast Proliferation after Laser Stimulation In Vitro Using Different Laser Types and Wavelengths (1064, 980, 635, 450, and 405 nm)—Preliminary Report

Assessment of Human Gingival Fibroblast Proliferation after Laser Stimulation In Vitro Using Different Laser Types and Wavelengths (1064, 980, 635, 450, and 405 nm)—Preliminary Report

Picosecond Q-Switched 1064/532 nm Laser in Tattoo Removal: Our Single Center Experience

Efficacy and Safety of 25% Trichloroacetic Acid Peel Versus 30% Salicylic Acid Peel in Mild-to-Moderate Acne Vulgaris: A Comparative Study

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