A new dinuclear Ag(I)–N-heterocyclic carbene complex derived from para-xylyl linked bis-imidazolium salt: synthesis, crystal structure, and in vitro anticancer studies

Synthesis, characterization, structural investigation, and antimicrobial studies of mononuclear Zn(II), Cd(II), and Ag(I) complexes of an N3O Schiff base

“…The antifungal activities of the compounds with respective MIC values indicated that 2 is as good as CdI 2 so the complex might have therapeutic potential if its toxicity is significantly diminished compared to CdI 2 . Dinuclear Ag(I)-N-heterocyclic carbene complex [29] exhibited potential activity against human colon cancer (HCT 116) and breast cancer (MCF-7), whereas our mononuclear N-coordinated Ag [47] reported the antimicrobial activities of diketimine metal complexes; in our study, we have tested the antimicrobial and antitumor activities of monoketimine metal complexes. In their case, all the complexes showed higher activity than the free ligand, but in our case, free L and 1 exhibit comparable inhibitory effect for S. typhimurium 11.…”

“…Though Cd(II) is a toxic metal [23], complexes have potential applications in catalysis [24], optical properties evolution [25], clathration [26], the vulcanization of diene rubbers [27], and in the treatment of hyperthyroidism [28]. Ag(I) ions are more attuned with biological system [29], with complexes exhibiting diverse coordination geometries as well as antimicrobial, antifungal, and anticancer activities [30][31][32].…”

Synthesis, crystal structures and spectroscopic properties of two new organotin (IV) complexes and their antiproliferative effect against cancerous and non-cancerous cells

“…DMSO (0.1%) was used as a negative control. Source of cell lines, culture conditions, preparation of cell culture and MTT assay were performed according to our previously reported procedure for these cell lines [39][40][41][42]. The details of cell culture conditions, preparation of cell culture and MTT assay procedure has been additionally provided in supplementary file.…”

<p>Synthesis, Characterization and DNA Binding Investigations of a New Binuclear Ag(I) Complex and Evaluation of Its Anticancer Property</p>

“…11 Among coinage metals, silver is of special importance since it is compatible with biological systems, and silver complexes display low toxicity to human cells, are selective against cancer cells, and act as antimicrobial agents. 8,12 A few active anticancer complexes of Ag(I) such as carboxylate, phosphane, and bipyridine complexes have been reported. [12][13][14] The presence of the ligands in the silver complexes leads to the improvement of the silver function.…”