A New Nano-Platform for Drug Release via Nanotubular Aluminum Oxide

Noh, Kunbae; Brammer, Karla S.; Choi, Chulmin; Kim, Seung Hyun; Frandsen, Christine J.; Jin, Sung‐Ho

doi:10.4236/jbnb.2011.23028

Cited by 26 publications

(12 citation statements)

References 40 publications

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“…Noh et al [138] designed a drug delivery system using aluminium oxide nanotubes. A model drug, amoxicillin, was loaded onto the internal nanotube structure and subsequently permitted to diffuse in a phosphate buffer saline solution (PBS) at a defined rate.…”

Section: Nanotubular Structuresmentioning

confidence: 99%

Electrodeposited conductive polymers for controlled drug release: polypyrrole

Alshammary

Walsh

Herrasti

et al. 2015

J Solid State Electrochem

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Over the last 40 years, electrically conductive polymers have become well established as important electrode materials. Polyanilines, polythiophenes and polypyrroles have received particular attention due to their ease of synthesis, chemical stability, mechanical robustness and the ability to tailor their properties. Electrochemical synthesis of these materials as films have proved to be a robust and simple way to realise surface layers with controlled thickness, electrical conductivity and ion transport. In the last decade, the biomedical compatibility of electrodeposited polymers has become recognised; in particular, polypyrroles have been studied extensively and can provide an effective route to pharmaceutical drug release. The factors controlling the electrodeposition of this polymer from practical electrolytes are considered in this review including electrolyte composition and operating conditions such as the temperature and electrode potential. Voltammetry and current-time behaviour are seen to be effective techniques for film characterisation during and after their formation. The degree of take-up and the rate of drug release depend greatly on the structure, composition and oxidation state of the polymer film. Specialised aspects are considered, including galvanic cells with a Mg anode, use of catalytic nanomotors or implantable biofuel cells for a self-powered drug delivery system and nanoporous surfaces and nanostructures. Following a survey of polymer and drug types, progress in this field is summarised and aspects requiring further research are highlighted.

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Section: Nanotubular Structuresmentioning

confidence: 99%

Electrodeposited conductive polymers for controlled drug release: polypyrrole

Alshammary

Walsh

Herrasti

et al. 2015

J Solid State Electrochem

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“…[72][73][74][75][76] Various drugs with different size and properties have been successfully performed on TNTs based on this concept, and these drugs …”

Section: Plasma Polymerized Biopolymer Coating Modificationsmentioning

confidence: 99%

Recent advances on smart TiO<sub>2</sub> nanotube platforms for sustainable drug delivery applications

Wang¹,

Huang²,

Li³

et al. 2016

IJN

107

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“…Anti-inflamatories like ibuprofen, indamethacin or naproxen that are orally administrated require high doses for correct absorption and affect other organs like liver or heart, have been successfully loaded and released from alumina reservoirs [53,55,60,66,67]. Other types of drugs like antibiotics, ophthalmic and immunosuppressive drugs or anticancer drugs like doxorubicin, have also been controllably delivered from alumina templates [40,68,69].…”

Section: Drug Deliverymentioning

confidence: 99%

Mesoporous alumina as a biomaterial for biomedical applications

Xifré-Pérez

Ferre-Borull

Pallarès

et al. 2015

Open Material Sciences

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Porous anodic alumina (PAA) is a biomaterial based on a cost-effective electrochemical anodization of pure aluminum with unique geometrical properties, i.e., self-ordering hexagonal pore distribution, tunable pore diameters and interpore distances, and uniformity of the pores in the vertical direction (nanochannels). These remarkable properties have found important applications in several fields such as energy storage, optics, photonics, magnetism, catalysis and, in particular, in the biomedicine field. In this work, we review the current state of research and key issues on cell culture and implants, drug delivery systems with complex release profiles and specific action, and high efficiency and sensitivity biosensors with different biosensing mechanisms, all of them based on PAA. The biocompatibility, morphology of the surface, nanoestructural engineering in-depth, surface functionalization and coatings are discussed and analyzed in detail.

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A New Nano-Platform for Drug Release via Nanotubular Aluminum Oxide

Abstract: ABSTRACT

Cited by 26 publications

References 40 publications

Electrodeposited conductive polymers for controlled drug release: polypyrrole

Electrodeposited conductive polymers for controlled drug release: polypyrrole

Recent advances on smart TiO<sub>2</sub> nanotube platforms for sustainable drug delivery applications

Mesoporous alumina as a biomaterial for biomedical applications

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A New Nano-Platform for Drug Release via Nanotubular Aluminum Oxide

Abstract: ABSTRACT

Cited by 26 publications

References 40 publications

Electrodeposited conductive polymers for controlled drug release: polypyrrole

Electrodeposited conductive polymers for controlled drug release: polypyrrole

Recent advances on smart TiO<sub>2</sub>&nbsp;nanotube platforms for sustainable drug delivery applications

Mesoporous alumina as a biomaterial for biomedical applications

Contact Info

Product

Resources

About

Recent advances on smart TiO<sub>2</sub> nanotube platforms for sustainable drug delivery applications