A new two-site model for hydroxyapatite dissolution in acidic media

Abstract

Production of carious lesions has long been associated with an attack of the enamel by various acids produced by the bacteria of the mouth (10-16). A simple model (1) was

Calculation of Intercrystalline Solution Composition during in Vitro Subsurface Lesion Formation in Dental Minerals†

“…25 The dissolution driving force for dental mineral has been found to be ∆C, the maximum amount of mineral per unit volume that can be potentially dissolved in a particular solution. 19,28,29 This is also taken as the solubility of the mineral in a particular solution. It should be noted that C s usually refers to the solubility of mineral in a sink solution, while ∆C is the solubility either in sink solution (then ∆C ) C s ) or in partially saturated solution (in this case, ∆C < C s ).…”

Mathematical modelling of tooth demineralisation and pH profiles in dental plaque

“…Because of its high relevance, dental caries problem has been intensively studied and, as soon as the computational power allowed it, the first mathematical models for tooth demineralisation (Holly and Grey, 1968;Zimmerman, 1966a, b, c;Fox et al, 1978) have been developed. As the experimental studies over the years offered more insight into the problem, new and more sophisticated numerical models emerged (Van Dijk et al, 1979;Ten Cate, 1982).…”

Geometric modeling of dissolution kinetics: Application to apatite

“…The precipitation of HAP is complicated because a number of calcium phosphate components can precipitate from a supersaturated solution. Because this compound is very similar to dahllite, the calcium phosphate in bones and teeth, medical researchers [Christoffersen et al, 1978;Fox et al, 1978], have studied its formation and dissolution to understand the process of bone resorption and caries formation. Soil researchers [Olsen, 1975;Smith et al, 1974Smith et al, , 1977½hien et al, 1980;Onlcen and Matheson, 1982] have examined the dissolution behavior of phosphate rock (PR), which consists mainly of apatite, because phosphorous is one of the two most important nutrients for agricultural productivity.…”

“…This kinetic model, describing a change in concentration going through a maximum as a function of time, is the sum of the parabolic and first-order reaction equations. The sum of the two rate terms (Table 1) In an effort to account for white spot formation in dental enamel, Fox et al [1978] developed a two-site model of HAP dissolution, each site with its own apparent solubility. In this model, dissolution at a site will occur only if the solution immediately adjacent to the site is undersaturated with respect to the site.…”