Robust detection of infrared small target is an important and challenging task in many photoelectric detection systems. Using the difference of a specific feature between the target and the background, various detection methods were proposed in recent decades. However, most methods extract the feature in a region with fixed shape, especially in a rectangular region, which causes a problem: when faced with complex-shape clutters, the rectangular region involves the pixels inside and outside the clutters, and the significant grey-level difference among these pixels leads to a relatively large feature in the clutter area, interfering with the target detection. In this paper, we propose a structure-adaptive clutter suppression method, called chain-growth filtering, for robust infrared small target detection. The well-designed filtering model can adjust its shape to fit various clutter structures such as lines, curves and irregular edges, and thus has a more robust clutter suppression capability than the fixed-shape feature extraction strategy. In addition, the proposed method achieves a considerable anti-noise ability by employing guided filter as a preprocessing approach and enjoys the capability of multi-scale target detection without complex parameter tuning. In the experiment, we evaluate the performance of the detection method through 12 typical infrared scenes which contain different types of clutters. Compared with seven state-of-the-art methods, the proposed method shows the superior clutter-suppression effects for various types of clutters and the excellent detection performance for various scenes.Remote Sens. 2020, 12, 47 2 of 22 decades, and they can be generally grouped into two categories: track-before-detect (TBD)-based methods and detect-before-track (DBT)-based methods.The TBD-based methods, such as pipeline filtering [11], hypothesis testing [12], 3-D matched filtering [13], temporal profile filtering [14], dynamic programming [15] and so on, try to use the grayscale consistency and the trajectory continuity of the targets in consecutive frames so as to discriminate the small targets from noise [16][17][18][19]. These methods are based on two assumptions; one is that the motion model of the target is known, the other is that the background motion is slow. In ideal conditions, both assumptions are satisfied; the energy of the targets is accumulated in adjacent frames, and the difference between targets and noise is increased. As a result, the TBD-based methods perform well in low signal-to-clutter conditions. However, in practical applications, we can hardly acquire the precise motion model of the targets, and the backgrounds can move fast when the infrared detector is in a moving platform. Therefore, both of the two assumptions could fail in real situations, and the performance of the TBD-based methods could degrade significantly [20]. Meanwhile, high time and storage requirements also make these TBD approaches unsuited to large-scale engineering projects [21].Compared with TBD-based methods, DBT-bas...