A novel methionine/palladium nanoparticle modified carbon paste electrode for simultaneous determination of three antiparkinson drugs

Abstract

A simple and novel method for the simultaneous determination of entacapone (EN), levodopa (LD) and carbidopa (CD) based on a methionine/palladium nanoparticle modified carbon paste electrode is described.

One-pot in situ synthesis of a CoFe2O4nanoparticle-reduced graphene oxide nanocomposite with high performance for levodopa sensing

“…5B) and the regression equation can be expressed as i pa (mA) ¼ 20.01n 1/2 (V s À1 ) 1/2 + 1.7441 (R 2 ¼ 0.9997) and i pc (mA) ¼ À10.43n 1/2 (V s À1 ) 1/2 À 0.7589 (R 2 ¼ 0.9940), respectively. These results indicate that the redox reaction of levodopa on the developed sensor is a diffusion controlled process, and the similar kinetics features were achieved at the gold screenprinted electrode, 32 methionine/palladium nanoparticle modi-ed electrode, 33 room temperature ionic liquid/NiO nanoparticle modied electrode 34 and carbon nanotubes-based composite modied electrodes. 35,36 Moreover, with the increase in scan rate, the oxidation peak potential positively shis while the reduction peak potential negatively shis.…”

Electroanalytical Determination of Escitalopram Oxalate Using Nickel Nanoparticles Modified Carbon Paste Sensor

“…The modified electrodes increase the selectivity and the sensitivity of electroanalytical processes more than the bare electrodes leading to increase in their analytical applicability. [37][38][39][40][41][42][43][44][45] On the other hand, nanoparticles have excellent electronic and electrocatalytic properties, which accelerate the rate of heterogeneous electron exchange between the electrode surface and some species in solution and increase the effective surface area of the working electrode. [46][47][48][49][50][51][52][53][54] The aim of this work is the study of the electrochemical behavior of ESC utilizing cyclic voltammetry (CV), differential pulse voltammetry (DPV) and electrochemical impedance spectroscopy (EIS) for the analysis of ESC in bulk powder, tablets and urine at nickel nanoparticles modified chloranil carbon paste sensor (NiCACP).…”

Thermal decomposition kinetics of the antiparkinson drug “entacapone” under isothermal and non-isothermal conditions

“…Various analytical methods have been used for ENT determination such as spectrophotometric [4,5], HPLC [6][7][8][9], micellar capillary chromatography [10,11] and electrochemical methods [12][13][14][15].…”