A novel microchip for capillary electrophoresis with acrylic microchannel fabricated on photosensor array

Mizukami, Yoshiaki; Rajniak, Daniel; Rajniak, Akiko; Nishimura, Masatoshi

doi:10.1016/s0925-4005(01)00953-4

Cited by 40 publications

(22 citation statements)

References 10 publications

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“…Although attempts to solve these problems of photometric detection are apparent [65,[112][113][114][115][116], at the same time we can see a significant increase of interest in the use of conductivity and amperometry detection techniques in the miniaturized CE as documented by recent reviews relevant to these topics [11][12][13][14]117].…”

Section: Closed Separation Compartment Of the Chip And The Detection mentioning

confidence: 99%

Electrophoretic separations on chips with hydrodynamically closed separation systems

et al. 2003

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This review focuses on capillary electrophoretic separations performed on capillary electrophoresis chips (CE chips) with hydrodynamically closed separation systems in a context with transport processes (electroosmotic flow (EOF)) and hydrodynamic flow (HDF)) that may accompany the separations in these devices. It also reflects some relevant works dealing with conventional CE operating under such hydrodynamic conditions. The use of zone electrophoresis (ZE), isotachophoresis (ITP) and their on-line combination (ITP-ZE) on the single-column and column-coupling CE chips with the closed separation systems and related problems are key topics of the review. Some attention is paid to sample pretreatment in the separations performed on the CE chips. Here, mainly potentialities of the ITP-ZE combination in trace analysis applications of the miniaturized systems are discussed in a broader extent. Links between the ZE separation and detection provide a frame for the discussion of current status of the detection on the CE chips. Analytical applications illustrate potentialities of the CE chips operating with the closed separation systems (suppressed HDF and EOF) to the determination of small ions present in various matrices by ZE, ITP and ITP-ZE.

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Section: Closed Separation Compartment Of the Chip And The Detection mentioning

confidence: 99%

Electrophoretic separations on chips with hydrodynamically closed separation systems

et al. 2003

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“…Unfortunately, the fabrication of the devices often creates a fair amount of scatter in the incident light and reduces the sensitivity. A new method of fabrication for these devices, by a novel stereo lithography [76], improves the detection limit by creating a smoother surface. Using this method a base plate and a cover plate are fabricated, and then a channel wall is fabricated between the base and the cover plate.…”

Section: Uv Absorptionmentioning

confidence: 99%

Capillary electrophoresis of proteins 2001–2003

Hutterer

Dolnı́k²

2003

Electrophoresis

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This review article with 244 references describes recent developments in capillary electrophoresis of proteins and covers the two years since the previous review (Dolník, V. Hutterer, K. Electrophoresis 2001, 22, 4163-4178) through Spring 2003. It covers topics related to CE of proteins including modeling of the electrophoretic properties of proteins, sample pretreatment, wall coatings, improving selectivity, detection, special electrophoretic techniques, and applications.

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“…Since their introduction more than 20 years ago, AM systems have been used in a variety of applications. These applications have ranged from the more conventional prototyping and rapid tooling (Radstok, 1999) to more advanced applications such as fabricating flexible cardiovascular models (Arcaute and Wicker, 2008), medical implants and tissue engineered constructs (Dhariwala et al, 2004;Arcaute et al, 2006;Lee et al, 2007;Choi et al, 2009b), 3D electronic devices (DeNava et al, 2008), micro-channels (Wicker et al, 2005b;Choi et al, in press) and various micro-systems (Mizukami et al, 2002;Palmer et al, 2006;Neumeister et al, 2006). There are numerous AM technologies available in the market.…”

Section: Introductionmentioning

confidence: 99%

Multi-material stereolithography

Choi

Kim

Wicker

2011

Journal of Materials Processing Technology

257

145

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a b s t r a c tA multi-material stereolithography (MMSL) machine was developed by retrofitting components from a commercial 3D Systems 250/50 stereolithography (SL) machine on a separate stand-alone system and adapting the components to function with additional components required for MMSL operation. The MMSL machine required construction of a new frame and the development of a new rotating vat carousel system, platform assembly, and automatic leveling system. The overall operation of the MMSL system was managed using a custom LabVIEW ® program, which included controlling a new vat leveling system and new linear and rotational stages, while the commercial SL control software (3D Systems Buildstation 4.0) was retained for controlling the laser scanning process. During MMSL construction, the sweeping process can be inhibited by previously cured layers, and thus, a deep-dip coating process without sweeping was used with low viscosity resins. Low viscosity resins were created by diluting commercial resins, including DSM Somos ® WaterShed TM 11120, ProtoTherm TM 12120, and 14120 White, with propoxylated (2) neopentyl glycol diacrylate (PNGD). Several multi-material complex parts were produced providing compelling evidence that MMSL can produce unique parts that are functional, visually illustrative, and constructed with multi-materials.

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A novel microchip for capillary electrophoresis with acrylic microchannel fabricated on photosensor array

Cited by 40 publications

References 10 publications

Electrophoretic separations on chips with hydrodynamically closed separation systems

Electrophoretic separations on chips with hydrodynamically closed separation systems

Capillary electrophoresis of proteins 2001–2003

Multi-material stereolithography

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