A Novel Use of Negative Ion Mobility Spectrometry for Measuring Electron Attachment Rates

Tabrizchi, Mahmoud; Abedi, Azra

doi:10.1021/jp048809b

Cited by 29 publications

(15 citation statements)

References 31 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Figures 2(c), 2(e), 2(g), and (i) show a tail between the two peaks at ~25 ms, which means that the ion at 26.2 ms, EL n H 3 O + , was converting into that at 24.5 ms, EL n H + , during the drift time. The tail can be used to calculate rate constants of ion‐molecule or decomposition reactions . However, EL n .H + and EL n .H 3 O + were expected to overlap.…”

Section: Resultsmentioning

confidence: 99%

Buffer gas modifiers effect resolution in ion mobility spectrometry through selective ion‐molecule clustering reactions

Fernandez‐Maestre

Hill

2012

Rapid Comm Mass Spectrometry

View full text Add to dashboard Cite

RATIONALE When polar molecules (modifiers) are introduced into the buffer gas of an ion mobility spectrometer, most ion mobilities decrease due to the formation of ion-modifier clusters. METHODS We used ethyl lactate, nitrobenzene, 2-butanol, and tetrahydrofuran-2-carbonitrile as buffer gas modifiers and electrospray ionization ion mobility spectrometry (IMS) coupled to quadrupole mass spectrometry. Ethyl lactate, nitrobenzene, and tetrahydrofuran-2-carbonitrile had not been tested as buffer gas modifiers and 2-butanol had not been used with basic amino acids. RESULTS The ion mobilities of several diamines (arginine, histidine, lysine, and atenolol) were not affected or only slightly reduced when these modifiers were introduced into the buffer gas (3.4% average reduction in an analyte's mobility for the three modifiers). Intramolecular bridges caused limited change in the ion mobilities of diamines when modifiers were added to the buffer gas; these bridges hindered the attachment of modifier molecules to the positive charge of ions and delocalized the charge, which deterred clustering. There was also a tendency towards large changes in ion mobility when the mass of the analyte decreased; ethanolamine, the smallest compound tested, had the largest reduction in ion mobility with the introduction of modifiers into the buffer gas (61%). These differences in mobilities, together with the lack of shift in bridge-forming ions, were used to separate ions that overlapped in IMS, such as isoleucine and lysine, and arginine and phenylalanine, and made possible the prediction of separation or not of overlapping ions. CONCLUSIONS The introduction of modifiers into the buffer gas in IMS can selectively alter the mobilities of analytes to aid in compound identification and/or enable the separation of overlapping analyte peaks.

show abstract

Section: Resultsmentioning

confidence: 99%

Buffer gas modifiers effect resolution in ion mobility spectrometry through selective ion‐molecule clustering reactions

Fernandez‐Maestre

Hill

2012

Rapid Comm Mass Spectrometry

View full text Add to dashboard Cite

show abstract

“…Ions in fields below 10 Td have T eff essentially equal to T, the temperature of the surrounding gas. The reactions of ions in ion mobility spectrometers under low field conditions at atmospheric pressure and well-defined temperatures can therefore provide kinetic and thermodynamic data [8][9][10][11][12][13][14][15].…”

Section: Introductionmentioning

confidence: 99%

A determination of the effective temperatures for the dissociation of the proton bound dimer of dimethyl methylphosphonate in a planar differential mobility spectrometer

Eiceman

Stone

2010

Int. J. Ion Mobil. Spec.

View full text Add to dashboard Cite

The dissociation of the proton bound dimer of dimethyl methylphosphonate to the protonated and neutral molecule has been studied in a planar differential mobility spectrometer. The internal energy of the ions is the sum of the thermal component and the electric field component and results in an effective temperature, T eff , that is significantly greater than that of the ambient atmosphere temperature, T. The measured rate constant for dissociation, which rises exponentially with field strength, together with activation energy and pre-exponential factor previously determined under thermal conditions, allow the calculation of T eff as a function of electric field strength. T eff is a linear function of electric field intensity at constant T over the range of T from 60°C to 140°C. The efficiency of the available collision energy in causing dissociation decreases with increasing T, from 52% at 60°C to 40% at 140°C.

show abstract

“…blistering agents) have also been measured using negative ion electrospray ionization (ESI)‐IMS,27 and negative ion APCI‐IMS has been used to study fluorinated phenols28 and non‐polar isomeric hydrocarbons 29. Negative ion APCI‐IMS has also been used to measure the reaction rate constants for electron attachment with CCl 4 , CHCl 3 , and CH 2 Cl 2 30. A review on the detection of explosives has been published10 and 2,4,6‐TNT has been used as a negative ion mobility standard 31…”

mentioning

confidence: 99%

New Highly Stable Metallabenzenes via Nucleophilic Aromatic Substitution Reaction

Lin

Zhang

et al. 2011

Chemistry A European J

View full text Add to dashboard Cite

Treatment of the ruthenabenzene [Ru{CHC(PPh(3))CHC(PPh(3))CH}Cl(2)(PPh(3))(2)]Cl (1) with excess 8-hydroxyquinoline in the presence of CH(3)COONa under air atmosphere produced the S(N)Ar product [(C(9) H(6)NO)Ru{CHC(PPh(3))CHC(PPh(3))C}(C(9)H(6)NO)(PPh(3))]Cl(2) (3). Ruthenabenzene 3 could be stable in the solution of weak alkali or weak acid. However, reaction of 3 with NaOH afforded a 7:1 mixture of ruthenabenzenes [(C(9)H(6)NO)Ru{CHC(PPh(3))CHCHC}(C(9)H(6)NO)(PPh(3))]Cl (4) and [(C(9)H(6)NO)Ru{CHCHCHC(PPh(3))C}(C(9)H(6)NO)(PPh(3))]Cl (5), presumably involving a P-C bond cleavage of the metallacycle. Complex 3 was also reactive to HCl, which results in a transformation of 3 to ruthenabenzene [Ru{CHC(PPh(3))CHC(PPh(3))C}Cl(2)(C(9)H(6)NO)(PPh(3))]Cl (6) in high yield. Thermal stability tests showed that ruthenabenzenes 4, 5, and 6 have remarkable thermal stability both in solid state and in solution under air atmosphere. Ruthenabenzenes 4 and 5 were found to be fluorescent in common solvents and have spectral behaviors comparable to those organic multicyclic compounds containing large π-extended systems.

show abstract

A Novel Use of Negative Ion Mobility Spectrometry for Measuring Electron Attachment Rates

Cited by 29 publications

References 31 publications

Buffer gas modifiers effect resolution in ion mobility spectrometry through selective ion‐molecule clustering reactions

Buffer gas modifiers effect resolution in ion mobility spectrometry through selective ion‐molecule clustering reactions

A determination of the effective temperatures for the dissociation of the proton bound dimer of dimethyl methylphosphonate in a planar differential mobility spectrometer

New Highly Stable Metallabenzenes via Nucleophilic Aromatic Substitution Reaction

Contact Info

Product

Resources

About