A pattern of lymphadenopathies seen in a tertiary care hospital in Lahore, Pakistan

Naseem, S.; Nagi, A. H.; Ashraf, Muhammad Aqueel; Bilal, Saira; Akhlaq, Maham; Henna, Nausheen; Sami, Waqas

doi:10.3906/sag-1001-546

Cited by 5 publications

(1 citation statement)

References 17 publications

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“…Similar findings have been obtained from some tropical and developing countries. [11][12][13][14] However, in a study by Damle et al conducted at a site in Maharashtra, the cases of tuberculous were not the most common finding reported. 1 The high prevalence of TB can be due to poor living conditions in underdeveloped and developing countries.…”

Section: Discussionmentioning

confidence: 99%

Analysis of the histopathological findings of lymph node biopsies at a tertiary care centre

et al. 2023

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Background: Lymph nodes are spread throughout the body and are routinely checked for abnormalities. These lymph nodes have the potential to become infected or malignant. The swelling of lymph nodes and the nodes which are abnormal in terms of size and/or number is commonly known as lymphadenopathy. One of the most common causes of lymphadenopathy observed is reactive lymphadenitis followed by granulomatous lymphadenitis. For diagnosis of lymph node biopsies, excisional biopsy and histopathological analysis are considered as the ‘gold standard’. Methods: This is a retrospective, descriptive and a cross-sectional study of all the patients with lymph node biopsies seen in Bhaktivedanta Hospital and Research Institute from January 2018 till March 2022. Histopathology reports of lymph node biopsies of patients required at Bhaktivedanta Hospital and Research Institute were included in the study. Results: The most common diagnosis is of tuberculous lymphadenitis which accounted for 251 (53.2%) of the total 469 cases. Tuberculous lymphadenitis was most commonly observed in females (68.92%) as compared to males (31.07%). Cancer cases which accounted for 83 (17.70%) cases formed the second most common diagnosis in which females (53.01%) accounted for most cases as compared to males (46.99%). Conclusions: Enlarged lymph nodes should undergo fine needle aspiration cytology (FNAC), truecut biopsy and/or excisional biopsy for correct diagnosis. The diagnostic spectrum ranges from benign reactive to TB and also malignancies.

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Section: Discussionmentioning

confidence: 99%

Analysis of the histopathological findings of lymph node biopsies at a tertiary care centre

et al. 2023

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Pattern of adult lymphadenopathy among patients attending King Khalid hospital, Majmaah province, Kingdom of Saudi Arabia

Abdelrahim¹,

Deyab²,

Mohamed³

et al. 2016

Int. J. Curr. Res. Med. Sci.

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Background: Although lymphadenopathy is a common presentation in clinical practice and no previous work was done in this region to assess it, this study was aimed to determine its causes and distribution among adult patients and highlight the gender, age, nationality of patients, number of enlarged lymph nodes and the commonest site of biopsies. Methods: Retrospectively data from lymph node biopsy specimens received at histopathology laboratory, King Khalid Hospital, Majmaah province, Saudi Arabia from January 2009 to December 2013 was reviewed and analyzed using SPSS version 21 software. Results: Of 54 cases of lymph node biopsies received, 28 (51.9%) were males and 26 (48.1%) were females giving male: female ratio 1.1: 1. The age of the patients ranged from 15 to 90 years. The commonest site of biopsies was cervical (61.1%) followed by mesenteric (20.4%) and axillary (11%). The benign pattern was observed in (72.2%) of cases while the malignant was observed in (27.8%) of cases. Malignant pattern was noticed more in elderly peoples with male predominance (60%). Reactive lymphoid hyperplasia (31.5%), tuberculous lymphadenitis (27.8%), Hodgkin`s lymphoma (13%) were the commonest causes of lymphadenopathy. Conclusions: Among the received cases of lymphadenopathy reactive lymphoid hyperplasia was found to be the most common cause followed by tuberculous lymphadenitis and hodgkin's lymphoma.

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Histopathological Evaluation of Lymph Node Biopsies: A Hospital Based Study

Rahman¹,

Biswas²,

Siddika

et al. 2012

J Enam Med Col

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Background: Lymphadenopathy is a common manifestation of a large variety of disorders,both benign and malignant. It is essential to define the pattern of disorders presenting primarily as lymph node enlargement in a particular environment. Histopathological examination of the lymph node biopsies is a gold standard test in the distinction between reactive and malignant lymphoid proliferations as well as for detailed subtyping oflymphomas. We designed this study in our population for histopathological evaluation of lymph nodes that might be helpful for clinical management of these lesions. Objective: Histopathological evaluation of lymphadenopathy from excised specimen, in relation to ageand sex of the patients, and distribution of the lymph nodes. Materials and Methods: It was a retrospective cross sectional study conducted in the department of Pathology, Enam Medical College & Hospital, Savar, Dhaka during the period from January 2006 to December 2010. Lymph node biopsies of all patients of both sexes and all age groups were included.Metastatic lymph nodes associated with evidence of primaries elsewhere in the body were excluded from the study. Total 191 lymph node biopsies were selected for histopathological evaluation. Among these 90 (47.12%) were from males and 101 (52.88%) were from females with male to female ratio being 1:2.1. The age of the patients ranged from 2 to 85 years with a mean age of 35.73 ± 18 years. Results: Cervical lymph nodes were the most common (56%) biopsied group. Of the 191 cases 59 cases (30.89%) were reactive lymphadenitis, 64 cases (33.5%) were tuberculosis, 2 cases (1.05%) were non-caseous granuloma, 11 cases (5.76%) were Hodgkin lymphoma, 22 cases (11.52%) were non-Hodgkin lymphoma, 24 cases (12.57%) were metastatic neoplasm and 9 cases (4.7%) were other lesions. Conclusion: Tuberculosis was the most common cause of lymphadenopathy, followed by reactive lymphadenitis and the cervical group of lymph nodes was most frequently affected

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A pattern of lymphadenopathies seen in a tertiary care hospital in Lahore, Pakistan

Cited by 5 publications

References 17 publications

Analysis of the histopathological findings of lymph node biopsies at a tertiary care centre

Analysis of the histopathological findings of lymph node biopsies at a tertiary care centre

Pattern of adult lymphadenopathy among patients attending King Khalid hospital, Majmaah province, Kingdom of Saudi Arabia

Histopathological Evaluation of Lymph Node Biopsies: A Hospital Based Study

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