“…Among the widely and successfully used methods are various Artificial neural networks (ANNs) 5 , response surface methodology (RSM) 7,8 , radial basis function (RBF) 8 , and fuzzy logic 9 .ANNs, as computational techniques, are nonlinear models designed to mimic the functionality and decisionmaking processes of the human brain 10 . ANNs have been increasingly applied in various environmental modeling studies 11,12 and investigations into water quality issues 13,14 . In the domain of wastewater treatment plant (WWTP) modeling, ANNs have been successfully employed for the prediction of WWTP parameters [15][16][17] , process control [18][19][20][21] , and the estimation of output parameters and characteristics 22,23 .…”