A Pharmaceutical Approach &amp; Antifungal Activities of Copper Soaps with their N &amp; S Donor Complexes Derived from Mustard and Soyabean Oils

Sharma, Arun Kumar

doi:10.19080/gjpps.2017.03.555619

Cited by 7 publications

(2 citation statements)

References 10 publications

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“…Several workers described the uses of copper soaps as stabilizers for nylon threads, synthetic polyamides and polyesters [5,6]. The protection of fabrics, nets, cordage etc from fungi and decay by impregnating them in ammonical solution of copper soaps was described by several workers [7,8]. The effectiveness of copper soaps as fungicides, bactericides, insecticides and herbicides were also studied.…”

Section: Introductionmentioning

confidence: 99%

Antimicrobial Studies and Characterization of Copper Surfactants Derived from Various Oils Treated at High Temperatures by P.D.A. Technique

Bhutra¹,

Sharma²,

Sharma³

2018

PHARMSCI

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Introduction: Biologically potent compounds are one of the most important classes of materials for the upcoming generations. Increasing number of microbial infectious diseases and resistant pathogens create a demand and urgency to develop novel, potent, safe and improved variety of antimicrobial agents. This initiates a task for current chemistry to synthesize compounds that show promising activity as therapeutic agents with lower toxicity. Therefore, a substantial research is needed for their discovery and improvement. Chemistry of present era aims to build a pollution free environment. For the same, it targets to create some alternativeswhich are eco-friendly and nature loving. Present research work is a step towards achieving such alternatives. Method: For this the metallic soaps of copper (derived from common edible oils) were synthesized. The synthesized copper soaps have been confirmed by elemental analysis, UV, and IR spectroscopic technique. The fungicidal activities of copper soaps derived from soyabean, sesame oils have been evaluated by testing against Alternaria alternate and Aspergillus niger by P.D.A. technique. Result: The fungi toxicity results indicate that the strain of fungal species are susceptible towards these soaps and suggests that with the increase in concentration of copper soap it may increase further. The transition metallic soaps showed good antifungal activity because chelation increases the anti-microbial potency.

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Section: Introductionmentioning

confidence: 99%

Antimicrobial Studies and Characterization of Copper Surfactants Derived from Various Oils Treated at High Temperatures by P.D.A. Technique

Bhutra¹,

Sharma²,

Sharma³

2018

PHARMSCI

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“…It is well known that study of absorption of ultrasonic waves in a medium provides important information about various inter and intra-molecular processes such as relaxation of the medium or the existence of isomeric states or the exchange of energy between various molecular degrees of freedom. [1][2][3][4][5][6] Derived parameters from ultrasonic velocity measurements provide qualitative information regarding the nature and strength of molecular interactions in liquid mixtures. 7,8 This has been studied for various binary and ternary mixtures with respect to variation in concentration of the liquids and temperatures.…”

Section: Introductionmentioning

confidence: 99%

Ultrasonic Studies of Copper Soap-urea Complexes Derived from Mustard and Soybean Oils

Sharma¹,

Saxena²,

Sharma³

2018

JPS

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Ultrasonic velocities and densities have been measured in ternary mixtures containing copper soap-urea complexes derived from mustard and soybean oils in 20% and 40% methanol-benzene mixture to assess the effect of polarity of solvent on the micellar features of surfactant. The studies suggest that predomination of benzene (higher percentage of non-polar solvent) plays a significant role in compacting the molecular organisation of the micelles. From these values, the ultrasonic velocity (u), the specific acoustic impedance (Z), adiabatic compressibility (β), intermolecular free length (L f), apparent molar compressibility (f k), molar sound velocity (R) and primary solvation number (S n) have been calculated. The data clearly indicate that the values of u, Z, S n and R increase whereas the values β and L f decrease consistently with increase in the soap complex concentration. The critical micelle concentration (CMC) has also been determined and it has been found that CMC is dependent on the composition of the solvent mixture and composition of the edible oil. The results have been analysed in terms of Masson's equation. The results have been explained on the basis of intermolecular interactions between solute and solvent molecules and effect of polarity and concentration were accessed on various acoustic parameters.

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Protection of wood against bio-attack and research of new effective and environmental friendly fungicides

Alabi

Abdulsalami

Ajibola

et al. 2023

Physical Sciences Reviews

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This research investigated the design, chemical modification, characterization and biocidal evaluation of waxes. Tallow (animal fat), bee-wax (insect) and shea butter (plant fat) were first converted to carboxylates by metathesis and later transformed into urea and thiourea complexes. The transformation was monitored using UV–visible, FT-IR and scanning electron microscopy (SEM) coupled with energy dispersive X-ray spectroscopy. They were also screened for biocidal activities using two white rots (Pleurotus sajor-cajor and Pleurotus oestratus), two brown rots (Sclerotium rolfsii and Rhizotonia solanii) and a soft rot (Cheatomium globosum). The UV–visible absorption peaks shifted to a longer wavelength for the complexes in relation to the carboxylates signifying lower energy and higher activities. Carboxylates showed very sharp peaks around 1700 cm−1 attributable to the carbonyl functional group (C=O) (Scheme 1), the carbonyl (C=O) peaks in the carboxylates were replaced by the appearance of another peaks in the urea and thiourea complexes at around 1600 cm−1 attributable to azomethine (C=N) (Scheme 2 and 3). None of the surface morphologies of the samples (crystalline) is identical. This result further confirmed the formation of the products. The result of fungi assay showed that tallow based carboxylate, urea and thiourea complexes greatly inhibited the growth of all the fungi species used. However, bees wax based carboxylate and its complexes as well as plant-fat based carboxylate and its complexes could not inhibit the growth of Sclerotium rolfsii. For insect and plant-based urea complexes, there were tiny growths (pin head) seen on the plates inoculated with P. sajor-cajor and P. oestratus, respectively. The findings of this work showed that urea and thiourea complexes performed better than carboxylates in fungi inhibition. Tallow-based products (carboxylates, urea and thiourea) showed the greatest anti-fungi properties.

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A Pharmaceutical Approach & Antifungal Activities of Copper Soaps with their N & S Donor Complexes Derived from Mustard and Soyabean Oils

Cited by 7 publications

References 10 publications

Antimicrobial Studies and Characterization of Copper Surfactants Derived from Various Oils Treated at High Temperatures by P.D.A. Technique

Antimicrobial Studies and Characterization of Copper Surfactants Derived from Various Oils Treated at High Temperatures by P.D.A. Technique

Ultrasonic Studies of Copper Soap-urea Complexes Derived from Mustard and Soybean Oils

Protection of wood against bio-attack and research of new effective and environmental friendly fungicides

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