A planning model for the WHO-EPI vaccine distribution network in developing countries

Chen, Sheng I.; Norman, Bryan A.; Rajgopal, Jayant; Assi, Tina Marie; Lee, Bruce Y.; Brown, Shawn T.

doi:10.1080/0740817x.2013.813094

Cited by 70 publications

(91 citation statements)

References 16 publications

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“…One of the studies also suggested the use of flow-down of products to the lowest level in the network, and the permitting of sufficient warm-up to avoid the end of horizon effects for vaccine distribution, to prepare for the potential impacts of an epidemic, (e.g. vaccine shortages, transportation delays, and product losses during distribution, storage, and/or transportation) ( Chen et al, 2014 ). Although not focused on commercial supply chains, Dasaklis et al (2012) confirmed the importance of logistics operations and their efficient management for handling epidemic disruptions such as polio, smallpox, cholera, and HIV.…”

Section: Review On Prior Epidemic Outbreaks and Disruptions In Supplymentioning

confidence: 99%

COVID-19 pandemic related supply chain studies: A systematic review

Chowdhury

Paul

Kaisar

et al. 2021

Transportation Research Part E: Logistics and Transportation Re

690

548

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The global spread of the novel coronavirus, also known as the COVID-19 pandemic, has had a devastating impact on supply chains. Since the pandemic started, scholars have been researching and publishing their studies on the various supply-chain-related issues raised by COVID-19. However, while the number of articles on this subject has been steadily increasing, due to the absence of any systematic literature reviews, it remains unclear what aspects of this disruption have already been studied and what aspects still need to be investigated. The present study systematically reviews existing research on the COVID-19 pandemic in supply chain disciplines. Through a rigorous and systematic search, we identify 74 relevant articles published on or before 28 September 2020. The synthesis of the findings reveals that four broad themes recur in the published work: namely, impacts of the COVID-19 pandemic, resilience strategies for managing impacts and recovery, the role of technology in implementing resilience strategies, and supply chain sustainability in the light of the pandemic. Alongside the synthesis of the findings, this study describes the methodologies, context, and theories used in each piece of research. Our analysis reveals that there is a lack of empirically designed and theoretically grounded studies in this area; hence, the generalizability of the findings, thus far, is limited. Moreover, the analysis reveals that most studies have focused on supply chains for high-demand essential goods and healthcare products, while low-demand items and SMEs have been largely ignored. We also review the literature on prior epidemic outbreaks and other disruptions in supply chain disciplines. By considering the findings of these articles alongside research on the COVID-19 pandemic, this study offers research questions and directions for further investigation. These directions can guide scholars in designing and conducting impactful research in the field.

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Section: Review On Prior Epidemic Outbreaks and Disruptions In Supplymentioning

confidence: 99%

COVID-19 pandemic related supply chain studies: A systematic review

Chowdhury

Paul

Kaisar

et al. 2021

Transportation Research Part E: Logistics and Transportation Re

690

548

View full text Add to dashboard Cite

show abstract

“…However, many potentially vaccine-preventable diseases in low-income countries are inadequately prevented due to an insufficient use of the existing vaccines. For instance, there is a lack of efficient distribution and delivery logistics, in addition to the associated high cost of the vaccine (Kochhar et al, 2013 ; Chen et al, 2014a ). Most of the current available vaccines are designed for subcutaneous or intramuscular administration.…”

Section: Relevance and Challenges In Oral Vaccine Developmentmentioning

confidence: 99%

Prospects on the Use of Schizochytrium sp. to Develop Oral Vaccines

Ramos‐Vega¹,

Rosales‐Mendoza

Bañuelos-Hernández

et al. 2018

Front. Microbiol.

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Although oral subunit vaccines are highly relevant in the fight against widespread diseases, their high cost, safety and proper immunogenicity are attributes that have yet to be addressed in many cases and thus these limitations should be considered in the development of new oral vaccines. Prominent examples of new platforms proposed to address these limitations are plant cells and microalgae. Schizochytrium sp. constitutes an attractive expression host for vaccine production because of its high biosynthetic capacity, fast growth in low cost culture media, and the availability of processes for industrial scale production. In addition, whole Schizochytrium sp. cells may serve as delivery vectors; especially for oral vaccines since Schizochytrium sp. is safe for oral consumption, produces immunomodulatory compounds, and may provide bioencapsulation to the antigen, thus increasing its bioavailability. Remarkably, Schizochytrium sp. was recently used for the production of a highly immunoprotective influenza vaccine. Moreover, an efficient method for transient expression of antigens based on viral vectors and Schizochytrium sp. as host has been recently developed. In this review, the potential of Schizochytrium sp. in vaccinology is placed in perspective, with emphasis on its use as an attractive oral vaccination vehicle.

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“…5 The Expanded Program of Immunization (EPI) was launched by the World Health Organization (WHO) in 1974, and Ethiopia has launched in 1980 to vaccinate all children. 6 , 7…”

Section: Introductionmentioning

confidence: 99%

Incomplete Vaccination and Its Predictors among Children in Ethiopia: A Systematic Review and Meta-Analysis

Desalew

Semahegn

Birhanu

et al. 2020

Global Pediatric Health

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Background. Vaccination is an effective public health intervention that has contributed to a substantial reduction in the burden of vaccine-preventable diseases. Abridged evidence on incomplete vaccination is not well established in Ethiopia. Therefore, this meta-analysis aimed to estimate the pooled prevalence of incomplete vaccination and its predictors among children aged 12 to 23 months. Methods. Primary studies conducted in Ethiopia were searched. The methodological quality of the included studies was assessed using the Joanna Briggs Institute (JBI) checklist. The analysis was conducted using STATA 14 and RevMan. The presence of statistical heterogeneity was checked using the Cochran Q test, and its level was quantified using I2 statistics. Pooled prevalence and odds ratio (OR) were computed at a 95% confidence interval (CI). Results. The pooled prevalence of incomplete vaccination was 30% (95% CI: 25-35). Maternal illiteracy (OR = 1.96; 95% CI: 1.40, 2.74) and home delivery (OR = 2.78; 95% CI: 2.28, 3.38) were associated factors that increased incomplete vaccination. However, maternal autonomy (OR = 0.54; 95% CI: 0.33, 0.89), maternal knowledge (OR = 0.31; 95% CI: 0.20, 0.47), husband employment (OR = 0.49; 95% CI: 0.35, 0.67), urban residence (OR = 0.61; 95% CI: 0.43, 0.86), ANC visits (OR = 0.30; 95% CI: 0.23, 0.39), postnatal care (OR = 0.39; 95% CI: 0.30, 0.52), and tetanus toxoid vaccine (3+) (OR = 0.42; 95% CI: 0.26, 0.69) were factors that reduced incomplete vaccination. Conclusion. In Ethiopia, 3 out of 10 children have incomplete vaccination. Policies should focus on strengthening and improving women’s education, maternal health knowledge, empowering women, and the utilization of prenatal care can overcome some of the barriers.

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A planning model for the WHO-EPI vaccine distribution network in developing countries

Cited by 70 publications

References 16 publications

COVID-19 pandemic related supply chain studies: A systematic review

COVID-19 pandemic related supply chain studies: A systematic review

Prospects on the Use of Schizochytrium sp. to Develop Oral Vaccines

Incomplete Vaccination and Its Predictors among Children in Ethiopia: A Systematic Review and Meta-Analysis

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