A practitioner's guide to necrotizing fasciitis

Harrington, Deedra; Lenahan, Christy McDonald; Sanders, Rachelle M.

doi:10.1097/01.npr.0000461947.30915.0c

Cited by 8 publications

(2 citation statements)

References 17 publications

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“…NF is a life-threatening infection, with reported mortality rates ranging from 8.7% to 73% (mean 32.2%) [8]. There are several risk factors for this condition, the most recognizable being immunodeficiency, diabetes, obesity, and alcohol abuse [9]. Rarely, NF can develop related to all-trans-retinoic acid, bisphosphonates, and radiotherapy [8].…”

Section: Discussionmentioning

confidence: 99%

Necrotizing fasciitis associated with sorafenib treatment

Kang

Yun

Kim

2019

IDCases

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Section: Discussionmentioning

confidence: 99%

Necrotizing fasciitis associated with sorafenib treatment

Kang

Yun

Kim

2019

IDCases

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“…Despite being rare, it may have a high mortality rate because it usually leads to rapidly progressing fascial necrosis (1,2). Its diagnosis is particularly challenging in early stages of the infection, and it may be confused with skin lesions of spider or insect bites (3,4). Surgical procedures, penetrating injuries (e.g., insect or animal bites), intravenous drug use, and minor interventional procedures, such as arthrocentesis or acupuncture, have all been described as potential predisposing factors for necrotizing fasciitis (3).…”

Section: Introductionmentioning

confidence: 99%

A Case of Necrotizing Fasciitis after Cryotherapy

Kayıpmaz¹,

Çelikel²,

Hasırcı³

et al. 2016

JAEMCR

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Introduction: Necrotizing fasciitis is a serious infection of the subcutaneous tissue and fascia. Despite being rare, it may have a high mortality rate because it usually leads to rapidly progressing fascial necrosis. The purpose of this study was to report a case of early stage necrotizing fasciitis that developed after cryotherapy for a penile condyloma, 19 days before the index emergency department admission. Case Report: A 32-year-old man without any history of systemic disorder was admitted to our emergency department for groin swelling and burning sensation that developed 12 hours before his hospital admission. Edema and hyperemia starting from the left inguinal region and extending to the penis and scrotum were noted on physical examination. While initially being considered a case of early stage necrotizing fasciitis and tested for it, the patient rapidly developed a bulla and entered intermediate stage. We hospitalized the patient with an initial diagnosis of necrotizing fasciitis and initiated dual antibiotic therapy. Furthermore, we debrided the wound and excised the necrotic tissue debris. We discharged the patient on the 12 th day.Conclusion: Clinical suspicion should be high for necrotizing fasciitis in emergency. Initiating the most appropriate medical and surgical therapy as soon as the diagnosis is made is the key for preventing mortality and morbidity.

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