A rare case of acral myxoinflammatory fibroblastic sarcoma at the hand

Abstract

One case of acral myxoinflammatory fibroblastic sarcoma is presented. Most of the soft tissue tumefactions of the distal extremities are benign. Sarcomas are rare and usually high grade. Acral myxoinflammatory fibroblastic sarcoma is a unique low-grade tumor described by Kindblom in 1998. This neoplasm has a propensity for digits, presents a low rate of metastasis and is characterized by a high rate of local multiple and aggressive recurrence. The clinical presentation, the frequent association with tenosynovitis and the extensive inflammatory infiltrate can lead to misdiagnosis by both the surgeon and the pathologist. Correct and early diagnosis depends on a good knowledge of histological and immunohistochemical findings. It is important to avoid recurrences recurring to an immediate wide excision of the tumor.

A case of lung metastasis in myxoinflammatory fibroblastic sarcoma: analytical review of one hundred and thirty eight cases

“…Regarding tumour location, initial reports overemphasised the predilection for distal extremities, so the term acral myxoinflammatory fibroblastic sarcoma was coined [2]. Although the adjective acral was deleted from the official nomenclature in 2002 because some cases are located axially [3], its use is still common [19,20,26,28,29,32,34,36,39,45]. Our analysis confirms that distal extremities are involved in the majority of cases, with hands and fingers being the most common sites.…”

Acral myxoinflammatory fibroblastic sarcoma: A case report and literature review

“…Three of their patients described a firm, painless mass noted incidentally while two patients described the mass as initially painless but becoming progressively more painful before seeking medical care. A similar presentation was noted by Leti Acciaro et al (20) in a subsequent report. These mimic the scenario in the present report, with the patient originally presenting with a diagnosis of chronic abscess and painless mass that became progressively more painful.…”

Giant myxoinflammatory fibroblastic sarcoma with bone invasion: a very rare clinical entity and literature review

“…The mass often grows slowly but can infiltrate into the surrounding soft tissues [5]. The tumoral bone invasion represented in the current case report is very rare.…”

“…Clinically, the invading tumor manifests as a slow-growing, painless mass that is characterized by a high rate of local recurrence and a low rate of metastasis. Cases have been reported over a wide age range; however, this rare tumor typically presents during the fourth to sixth decades of life, without a gender predilection[5],[6]. Histologically, the lesions are composed of a myxoid matrix containing numerous inflammatory cell types, fibrosis, and scattered large tumor cells.…”