A remote metastatic giant cell tumour to the skull

Abstract

This case discusses an unusual presentation of remote metastatic giant cell tumour presenting as a seizure.

Surgical management of giant cell tumor invading the occipital bone: A case report and literature review

“…[34,35] e clinical presentation of GCTB in the occipital area is usually described as a tender and swollen lesion accompanied by headache, neck pain, vomiting or swelling of the affected area, and, less commonly, seizures. [55,23] Furthermore, depending on the tumor extension into the neighboring area, it might cause lower cranial nerve deficits. [51] Differential diagnosis e differential diagnosis of GCTB includes giant cell reparative granuloma, Paget's disease of the bone, aneurysmal cyst bone, chondroblastoma, chondromyxoid fibroma, nonossifying fibroma, fibrous dysplasia, pigmented villonodular synovitis, foreign body reactions, and brown tumors from hyperparathyroidism.…”

“…The clinical presentation of GCTB in the occipital area is usually described as a tender and swollen lesion accompanied by headache, neck pain, vomiting or swelling of the affected area, and, less commonly, seizures. [ 55 , 23 ] Furthermore, depending on the tumor extension into the neighboring area, it might cause lower cranial nerve deficits. [ 51 ]…”

“…[2,12] Particularly, few cases have been reported in the occipital bone compared to the temporal, frontal, sphenoid, and ethmoidal bones. [4][5][6][7]13,[15][16][17]19,[21][22][23]26,[28][29][30][31]33,37,43,45,[47][48][49]51,[53][54][55] Weng et al reported that the overall distribution of cases in the occipital bone was 9.8%. [51] is tumor is more common among adults, and gender distribution has been previously reported to be more common in females.…”

“…[12] We conducted a review of the literature, which yielded 27 reported cases of GCTB originating in the occipital bone (retrieval of full-text information, including patient sex and age, type of treatment, and presence of recurrence during the follow-up was possible in 22 cases, and is shown in Table 1). [1,4,7,13,[15][16][17][21][22][23]26,[28][29][30][31]33,43,45,[47][48][49]51,54,55] To the best of our knowledge, this is the first case of a GCTB of the occipital bone in a Hispanic patient. Besides, our review constitutes the most comprehensive compilation of cases in the occipital region.…”

“…[ 2 , 12 ] Particularly, few cases have been reported in the occipital bone compared to the temporal, frontal, sphenoid, and ethmoidal bones. [ 4 - 7 , 13 , 15 - 17 , 19 , 21 - 23 , 26 , 28 - 31 , 33 , 37 , 43 , 45 , 47 - 49 , 51 , 53 - 55 ] Weng et al . reported that the overall distribution of cases in the occipital bone was 9.8%.…”