A retrospective PCR investigation of avian Orthoreovirus, chicken infectious anemia and fowl Aviadenovirus genomes contamination in commercial poultry vaccines in Brazil

Barrios, Priscilla Rochele; Marin, S. Y.; Ríos, R.; Pereira, C.G.; Resende, Maria Aparecida de; Resende, J.S.; Martins, N. R. S.

doi:10.1590/s0102-09352012000100035

Cited by 7 publications

(5 citation statements)

References 10 publications

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“…Contamination of vaccines with CAV has been known since 1979 [7], when the agent was first described. In Brazil, a retrospective study with commercial vaccines detected CAV contamination in vaccine batches from some laboratories until 1997, but not in 13 batches of distinct vaccines produced by five distinct laboratories from 2001 onwards [8]. However, the results obtained in the present study demonstrate the presence of CAV genomes in recently produces vaccines, substantiating the need for improved control measures to avoid CAV contamination.…”

Section: Discussioncontrasting

confidence: 40%

Chicken anemia virus and avian gyrovirus 2 as contaminants in poultry vaccines

Varela¹,

Santos²,

Cibulski³

et al. 2014

Biologicals

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Section: Discussioncontrasting

confidence: 40%

Chicken anemia virus and avian gyrovirus 2 as contaminants in poultry vaccines

Varela¹,

Santos²,

Cibulski³

et al. 2014

Biologicals

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“…Immunosuppressive diseases usually negatively affect chickens of the poultry industry by increasing the susceptibility to opportunistic infections by viruses and bacteria (Lutticken, 1997;Balamurugan & Kataria, 2006). Among the known immunosuppressive agents, CAV stands out for its worldwide occurrence, not only in commercial poultry, but also in SPF chickens (Schat, 2003;Balamurugan & Kataria, 2006), backyard chickens (Barrios et al, 2009), as well as contaminates poultry vaccines (Barrios et al, 2012). CAV presents tropism for T-lymphocytes, rendering the cellular immune response ineffective, especially in young chickens, by destroying CD8+ T cells (Adair et al, 1993;Adair, 2000;Brentano, 2009), disabling the protection against intracellular agents.…”

Section: Discussionmentioning

confidence: 99%

Experimental Coinfection of Chicken Anemia Virus and Mycoplasma gallisepticum Vaccine Strains in Broiler Chicks

Prezotto

Marin

Araújo

et al. 2016

Rev. Bras. Cienc. Avic.

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“…Barrios et al (2011) found FAdV DNA in 3/26 live poultry vaccines produced from 1991 to 1994, but no detection in the following years up to the present. The results indicated a role for live vaccines in the epidemiology of FAdV, possibly partially related to its widespread occurrence, as detected in our results.…”

Section: Resultsmentioning

confidence: 76%

“…This is an important disease, previously unknown in the poultry industry, which primarily affects broiler chickens at 3-6 weeks of age and is characterized by sudden onset and high mortality (Abdul-Aziz and Hasan, 1995). A FAdV investigation in 28 poultry vaccines, 26 live and 2 inactivated, was published recently (Barrios et al, 2011), and found FAdV DNA in live vaccines, produced in Jan/1991, May/1992 (Newcastle disease) and Jan/1994 (avian encephalomyelitis), all by the same manufacturer.…”

Section: Introductionmentioning

confidence: 99%

Occurrence of Aviadenovirus in chickens from the poultry industry of Minas Gerais

Pereira

Marin

Santos

et al. 2014

Arq. Bras. Med. Vet. Zootec.

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The occurrence of Aviadenovirus (FAdV) was investigated in chickens from the poultry industry of Minas Gerais state, Brazil. The investigation was conducted due to the scarcity of recent data in the country and its description in neighboring countries. For this purpose, livers were collected from layer chicks (n=25), older layers (n=25), broilers (n=300), and livers (n=25) and stool (n=25) samples from broiler breeders, representing the major poultry regions of the state. FAdV DNA was demonstrated using a previously described PCR protocol for amplifying part of the hexon gene encoding sequence. FAdV was found in layer chicks (36%), widespread (100%) in older layers, and with regional differences in broilers (24-86%). Although all broiler breeder stools were negative, FAdV DNA was detected in livers (16%, 4/25) of stool-negative birds. In order to obtain additional information on the circulation of the infection, livers of subsistence chickens collected from one poultry intensive region, were evaluated (n = 12), with FAdV being detected in all samples. FAdV was found in young and old layers, broilers, broiler breeders and free-range chickens, and results suggest the circulation of FAdV among different types of chickens. The detection in older layer chickens may indicate an extended risk of horizontal transmission in regions of Minas Gerais with mixed activity of egg and meat type chickens and poor biosecurity strategies. The infection in breeders may indicate vertical transmission and the continuous production of infected progenies. The hexon-gene-targeted PCR amplicon sequences aligned with FAdV of species D of Aviadenovirus. Results indicate the necessity for biosecurity, especially for breeders, separating flocks according to origin, age and health status, which will be an advantage regarding any pathogen.Keywords: Aviadenovirus, FAdV, layer chicken, broiler chicken, broiler breeder RESUMO Descreve-se a ocorrência de Aviadenovirus (FAdV) na avicultura mineira. Foram amostrados fígados de poedeiras jovens (n=25) e velhas (n=25) e de frangos de corte (n=300). Em matrizes pesadas foram amostrados fígados (n=25) e fezes (n=25). O estudo envolveu as principais regiões avícolas do Estado de

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A retrospective PCR investigation of avian Orthoreovirus, chicken infectious anemia and fowl Aviadenovirus genomes contamination in commercial poultry vaccines in Brazil

Cited by 7 publications

References 10 publications

Chicken anemia virus and avian gyrovirus 2 as contaminants in poultry vaccines

Chicken anemia virus and avian gyrovirus 2 as contaminants in poultry vaccines

Experimental Coinfection of Chicken Anemia Virus and Mycoplasma gallisepticum Vaccine Strains in Broiler Chicks

Occurrence of Aviadenovirus in chickens from the poultry industry of Minas Gerais

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