A Review on Pharmacological Activities of Alkaloids

Abstract

Alkaloids are a category of molecules in nature around the globe with a relatively large occurrence. These are chemicals and biomolecules that are very complex. Alkaloids are compounds of a very diverse class of secondary plant metabolites; alkaloids, such as anticholinergic, antitumor, diuretic, antiviral, antihypertensive, antiulcer, analgesic, and anti-inflammatory, have been linked to extensive list of biological activities. The basic character of alkaloids allows salts to be formed with mineral acids or organic acids, alkaloid salts are usually soluble in water and dilute alcohols, and are not soluble in organic solvents except in rare cases. This research is carried out mainly in the context and classification of alkaloids and alkaloids pharmacological practices.

Electrochemically Enabled Total Syntheses of Natural Products

“…Alkaloids are critically important natural products and vital inspiration toward active pharmaceutical and chemotherapeutic agents. [122] Nitrogen-containing compounds and particularly Nheterocycles are generally considered privileged scaffolds in medicinal chemistry; [123] facile access to and functionalization of these compounds are an essential toolset for both total synthetic and drug discovery efforts. These efforts can be complicated by solubility issues associated with polar amines, the tendency of Lewis basic nitrogen atoms to engage electrophilic reagents and transition metal catalysts, and other liabilities imparted by the heteroatom that often necessitate various protective chemistries.…”

“…Alkaloids are critically important natural products and vital inspiration toward active pharmaceutical and chemotherapeutic agents [122] . Nitrogen‐containing compounds and particularly N ‐heterocycles are generally considered privileged scaffolds in medicinal chemistry; [123] facile access to and functionalization of these compounds are an essential toolset for both total synthetic and drug discovery efforts.…”