A simple chalcone based ratiometric chemosensor for sensitive and selective detection of Nickel ion and its imaging in live cells

Bis‐Pyridyl Diimines as Selective and Ratiometric Chemosensor for Ni(II) and Cd(II) Metal Ions

“…The ring strain associated with chelation may be reason for higher wavenumber for C=N and C=C than in free 2pdab . Also in free 2pdab , the extent of delocalization of electron density is much more than when it is chelated with some metal.…”

“…The comparison of 2pdab with different well reported nickel sensor is shown in Figure and table S1. Prabhu et al . established a chalcone based fluorescent chemosensor for nickel which has a detection limit up to micro molar level (5.14 μM) and binding constant is 1.91×10 5 M −1 (Figure a).…”

“…Recently, Prabhu and co‐workers developed a highly selective fluorescent chemosensor based on pyrene‐conjugated pyridine for Nickel ion. The ratiometric sensing of Nickel ions by the chemosensor is due to the formation of a monomer‐excimer emissions and it was effective in detecting the Ni 2+ ion in biological samples . Recently Goswami group also developed a ratiometric chemosensor based on quinoxaline derivative, which is naked eye detection for Ni +2 ion …”

Colorimetric chemosensor for Ni2+ based on alizarin complexone and a cationic polyelectrolyte in aqueous solution

“…Currently, several analytical methods have been explored for the determination of Ni 2+ concentration, such as atomic absorption spectrometry, inductively coupled plasma mass spectrometry, liquid chromatography, electrochemical methods, and fluorescence techniques . Although all of these techniques offer highly selective, sensitive and accurate quantification of metal ions, they usually require sophisticated equipment, high operation cost, and complex sample preparation processes.…”

Electrochemical Detection of Ni2+ Ions Using Synthesized (E)‐N’‐Chlorobenzylidene‐4‐methylbenzenesulfonohydrazide Derivatives Modified with a Nafion Matrix

“…Ni 2+ exposition can cause poisonous effects for example asthma, contact allergy, dermatitis, gastrointestinal distress, cancer (lung, oral cavity, and larynx), kidney & sinus problem, promotion of disorders in CNS, and pulmonary fibrosis. HMI can be easily absorbed by animals and plants, and then may mount up in the human body by way of food chain . Owing to the dangerous consequence of HMI, it is very imperative and important to discover advantageous, efficient, and practicable technique to treat wastewater containing poisonous metal pollutants, and remove their dangerous effects on ecology and human health.…”