A small dose of droperidol decreases postoperative nausea and vomiting in adults but cannot improve an already excellent patient satisfaction

Hechler, A.; Neumann, Sabine; Jehmlich, M.; Lange, U.; Hopf, Hans‐Bernd

doi:10.1034/j.1399-6576.2001.045004501.x

Cited by 14 publications

(7 citation statements)

References 24 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Most studies report a greater than 90% satisfaction rate with anesthesia services. 21,22 Correspondingly, patients in this study were extremely satisfied with their anesthesia care ( Figure 2). With such high satisfaction rates, an extremely large patient population would be required to demonstrate an improvement in overall patient satisfaction.…”

Section: Discussionmentioning

confidence: 82%

Preoperative intravenous midazolam: benefits beyond anxiolysis

Bauer

Dom

Ramírez

et al. 2004

Journal of Clinical Anesthesia

101

View full text Add to dashboard Cite

Section: Discussionmentioning

confidence: 82%

Preoperative intravenous midazolam: benefits beyond anxiolysis

Bauer

Dom

Ramírez

et al. 2004

Journal of Clinical Anesthesia

101

View full text Add to dashboard Cite

“…In der Praxis ist es häufig noch üblich, das PONV-Risiko anhand eines einzelnen Faktors,wie beispielsweise des operativen Eingriffs oder der PONV-Anamnese einzuschät-zen.Leider ist aber die Vorhersage anhand eines einzelnen Prädiktors wenig sensitiv.Wenn überhaupt ein einzelner Risikofaktor verwendet werden sollte, dann weist die von der Arbeitsgruppe um Hopf vorgeschlagene Einteilung nach dem Geschlecht die beste Sensitivität und Spezifität auf [34].Demnach würden alle Frauen,nicht jedoch Männer eine antiemetische Prophylaxe erhalten.Grund ist unter anderem,dass sowohl PONV in der Anamnese als auch der Nichtraucherstatus das Risiko weniger beeinflussen als das Geschlecht (geringere Odds ratio) und im Durchschnitt das Risiko bei Männern deutlich unter 20% liegt. Die begrenzte Aussagekraft eines einzelnen Risikofaktors hat dazu geführt, dass anhand mehrerer Faktoren Risikoscores entwickelt wurden, die zum Teil sogar eine Risikoabschätzung in Prozent liefern [3,4,38,39,51,58].…”

Section: Modelle Zur Risikoeinschätzungunclassified

Postoperative �belkeit und Erbrechen

Roewer

2004

Anaesthesist

108

View full text Add to dashboard Cite

Numerous pathophysiological mechanisms are known to cause nausea or vomiting but their role for postoperative nausea and vomiting (PONV) is not quite clear. Volatile anesthetics, nitrous oxide and opioids appear to be the most important causes for PONV. Female gender, non-smoking and a history of motion sickness and PONV are the most important patient specific risk factors. With these risk factors an objective risks assessment is achievable as a good rational basis for a risk dependent antiemetic approach: When the risk is low, moderate, or high, the use of none, a single or a combination of prophylactic antiemetic interventions seems to be justified. Performing a total intravenous anesthesia (Ti.v.A) with propofol is a reasonable prophylactic approach, but does not solve the problem satisfactorily alone if the risk is very high, reducing the risk of PONV only by 30%. This is comparable to the reduction rate of antiemetics, such as serotonin antagonist, dexamethasone and droperidol. It must be stressed that metoclopramide is ineffective. Data from IMPACT indicate that prophylaxis is not very effective if the patients risk is low. At a moderate risk the use of Ti.v.A or an antiemetic is reasonable and only a (very) high risk justifies the combination of several prophylactic antiemetic interventions. For the treatment of PONV an antiemetic should be chosen which has not been used prophylactically. The necessary doses are usually a quarter of those needed for prophylaxis.

show abstract

“…A variety of causes of PONV have been described, including age, (10,14) female gender, (3,4,10,(14)(15)(16) type of surgery, (10,14,15) length of surgical procedure, (4,14,17) perioperative use of opioids, (7,10,(18)(19)(20)(21) anxiety, (14) history of motion sickness, (14,22) prior history of PONV, (14) anesthetic agent, (23,24) nonsmoker, (25) obesity, (14) and gastroparesis. (14) Although female patients are more likely to have PONV, there is not necessarily a relationship with the phase of menses, (26) although there is a report of increased PONV in the periovulatory and premenstrual periods.…”

Section: Causesmentioning

confidence: 99%

“…Older traditional antiemetics include scopolamine, (8) phenothiazines (promethazine (8) ), antihistamines (diphenhydramine), (8) butyrophenones (droperidol), (l2, 3,8,9,21,[40][41][42][43][44] benzamides (metoclopramide), (8,21,42,(45)(46)(47) perphenazine, (42) prochloperazine, (42) cyclizine, (42) and dimenhydrinate. (2) Dimenhydrinate gave only a marginal reduction in PONV.…”

Section: Treatmentmentioning

confidence: 99%

See 1 more Smart Citation

Postoperative Nausea and Vomiting: Cause, Prevention, and Treatment

Shiffman¹

2003

International Journal of Cosmetic Surgery and Aesthetic Dermato

View full text Add to dashboard Cite

Postoperative nausea and vomiting (PONV) occur in an average of 20-40% of patients. There are many drugs and combinations of drugs for the prevention and treatment of PONV. Prophylactic antiemetics should be considered in the high-risk patient (prior history of motion sickness, past history of PONV, certain surgical procedures such as strabismus surgery and middle ear surgery). Avoid perioperative opioids, which are known to cause PONV, when possible by substituting a drug such as Stadol. Female nonsmokers have a higher risk for PONV than other groups, but there probably would not be an indication to use prophylactic agents in such patients unless another risk factor is also present. 87

show abstract

A small dose of droperidol decreases postoperative nausea and vomiting in adults but cannot improve an already excellent patient satisfaction

Abstract: Routine PONV prophylaxis with 20 microg x kg(-1) body weight of droperidol is cost-efficient and appropriate in women but not in men.

Cited by 14 publications

References 24 publications

Preoperative intravenous midazolam: benefits beyond anxiolysis

Preoperative intravenous midazolam: benefits beyond anxiolysis

Postoperative �belkeit und Erbrechen

Postoperative Nausea and Vomiting: Cause, Prevention, and Treatment

Contact Info

Product

Resources

About