A spectrophotometric-partial least squares (PLS-1) method for the simultaneous determination of furosemide and amiloride hydrochloride in pharmaceutical formulations

Ferraro, Mónica C.F.; Castellano, Patricia M.; Kaufman, Teodoro S.

doi:10.1016/s0731-7085(01)00432-0

Cited by 62 publications

(23 citation statements)

References 27 publications

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“…The methods like spectrophotometry (8,9) , variable-angle scanning fluorescence spectrometry (10) , spectrofluorimetry (11)(12) , potentiometry (13) , voltammetry (14) and chromatography (15 -17) . were used.…”

Section: Fig 1 Chemical Structure Of Bumetanidementioning

confidence: 99%

Characterization of Eu(III) Complex for Determination of Bumetanide in Pharmaceutical Preparations and in Biological Fluids

2016

Egypt. J. Chem.

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Section: Fig 1 Chemical Structure Of Bumetanidementioning

confidence: 99%

Characterization of Eu(III) Complex for Determination of Bumetanide in Pharmaceutical Preparations and in Biological Fluids

2016

Egypt. J. Chem.

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“…Selection of the most appropriate wavelength intervals for calibration/prediction was carried out by means of a minimum PRESS search through a variable size moving-window [13], while PLS1 data evaluation was performed with an in-house set of routines [14] written for Matlab according to [15] and [16]. Spectra were mean-centred for calibration and prediction.…”

Section: Dissolution Profilesmentioning

confidence: 99%

Chemometrics-assisted simultaneous determination of atenolol and chlorthalidone in synthetic binary mixtures and pharmaceutical dosage forms

Ferraro

Castellano

Kaufman

2003

Analytical and Bioanalytical Chemistry

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Resolution of binary mixtures of atenolol (ATE) and chlorthalidone (CTD) with minimum sample pre-treatment and without analyte separation has been successfully achieved, using a new and rapid method based on partial least squares (PLS1) analysis of UV spectral data. The simultaneous determination of both analytes was possible by PLS1 processing of sample absorbances between 255 and 300 nm for ATE and evaluation of absorbances in the 253-268 nm region for CTD. The mean recoveries for synthetic samples were 100.3 +/- 1.0% and 100.7 +/- 0.7% for ATE and CTD, respectively. Application of the proposed method to two commercial tablet preparations in the content uniformity test showed them to contain 103.5 +/- 0.8% and 104.9 +/- 1.8% ATE respectively, as well as 103.4 +/- 1.2% and 104.5 +/- 2.2% CTD. Use of this method also allowed the elaboration of dissolution profiles of the drugs in two commercial combined formulation products, through the simultaneous determination of both drugs during the dissolution test. At the dissolution time of 45 min specified by USP XXIV, both pharmaceutical formulations complied with the test.

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“…Several methods have been reported for the determination of the components of this important drug (furosemide). Titrimetric methods [3][4][5][6][7], Potentiometric methods [8,9] Ultraviolet methods [10][11][12][13][14][15][16], Colorimetric methods [17][18][19][20][21][22][23][24][25][26][27][28][29][30][31][32][33][34][35].…”

Section: Introductionmentioning

confidence: 99%

Spectrophotometric Determination of Furosemide Drug in Different Formulations using Schiff ’s Bases

Hassouna¹

2016

FRCIJ

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Simple, accurate and reproducible UV spectrophotometric method was established for the assay of Fourosemide based on the formation of Schiff 's bases coupling with aromatic aldehydes such as benzaldehyde, salicylaldehyde, 2-methoxy benzaldehyde, anisaldehyde, vanilline, 2,3,4-chlorobenzaldehyde, 4-nitro benzaldehyde and dimethylaminobenzaldehyde in presence of sulphuric acid, The optical characteristics such as Beer's law limits, molar absorptivity and Sandell's sensitivity for the methods are given. Regression analysis using the method of least squares was made to evaluate the slope (b), intercept (a) and correlation coefficient (r) and standard error of estimation (SE) for each aldehyde. Determination of furosemide in bulk form and in pharmaceutical formulations were also incorporated.

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A spectrophotometric-partial least squares (PLS-1) method for the simultaneous determination of furosemide and amiloride hydrochloride in pharmaceutical formulations

Cited by 62 publications

References 27 publications

Characterization of Eu(III) Complex for Determination of Bumetanide in Pharmaceutical Preparations and in Biological Fluids

Characterization of Eu(III) Complex for Determination of Bumetanide in Pharmaceutical Preparations and in Biological Fluids

Chemometrics-assisted simultaneous determination of atenolol and chlorthalidone in synthetic binary mixtures and pharmaceutical dosage forms

Spectrophotometric Determination of Furosemide Drug in Different Formulations using Schiff ’s Bases

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