A study of mortality in dermatology

Nair, Pradeep S.; Moorthy, Prasanna K; Yogiragan, K.

doi:10.4103/0378-6323.13781

Cited by 21 publications

(21 citation statements)

References 3 publications

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“…The death rate found in our study was slightly higher than that of Tollhupp-Journet et al 2 in France and Keita et al 3 in Guinea with 9% and 7.90%, far higher than Nair et al 4 3.58% in India in Dermatology services. Compared to those of studies conducted in Côte d'Ivoire in other services, our mortality rate substantially corresponds to that found by Dekou A et al 5 (10.1%) in a urology Abidjan.…”

Section: Discussioncontrasting

confidence: 73%

Analysis of Mortality in a Dermatological Affections Referral Center in Sub-Saharan Africa, Abidjan, République de Côte d'Ivoire

Joseph¹,

Isidore²,

Alexandre³

et al. 2016

Dermatol Open J

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Objectives: To document patients who died in Dermatology Department at University Teaching Hospital (UTH) of Treichville; describe epidemiological aspects; indicate the various dermatological diseases associated; specify the immediate causes; identify the determinants. Materials and Methods: This was a cross-sectional study with descriptive and analytical referred. Included were all hospitalized patients died in the Dermatology and Venereology service of Treichville University Hospital from January 2000 through December 2014. Results: One thousand seven-hundred and thirty-five patients were hospitalized. The hospital mortality was 10.26% (178 deaths). The average age of the death was 43.16 years; the sex ratio was 0.83. Patients who had no source of income were the most numerous (61.53%). The average hospital stay was 20.05 days. Patients had at the entrance an altered condition in 49.43% of cases and 46.62% in middle condition. Those who regularly bought their drugs were 58.21%. Those who died in the second half of the month were the most numerous (55.61%). Dermatosis groups associated deaths were: infectious dermatosis 41.57%, 29.77% tumor dermatitis and drug eruptions 16.85%. Of the 178 deaths, the 1 st 3 are pathologies associated fasciitis (50 cases), Kaposi's sarcoma (46 cases) and toxic epidermal necrolysis (17 cases). Respiratory distress (41.31%) and septic shock (36.52%) were the main immediate causes of death. Anemia (41.40%), tuberculosis (10.82%) and diabetes (10.19%) were the major comorbidities. Serology was positive in 92.5% of dead patients who have realized their HIV status (n=80). Significantly associated determinants were essentially the regular bought of drugs (p=0.013), the altered condition (p=0.033), death hours (p=0.023) and comorbidities (p=00000). Conclusion: Mortality is a reality in the Dermatology and Venereology at UTH of Treichville. These determinants are numerous and some need to be better studied to identify true risk factors in order to make appropriate recommendations.

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Section: Discussioncontrasting

confidence: 73%

Analysis of Mortality in a Dermatological Affections Referral Center in Sub-Saharan Africa, Abidjan, République de Côte d'Ivoire

Joseph¹,

Isidore²,

Alexandre³

et al. 2016

Dermatol Open J

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“…In our ward, sepsis contributed to 68.2% of all deaths during the study period, while in another study, it contributed to 10.8% deaths. [3] Sepsis associated high mortality rates have been reported from various burn units (29.1%-71.4%), surgical wards and ICUs (30%-50%) both in India and abroad. [5][6]18,[20][21][22] This is comparable to that observed in our patients (37.5%).…”

Section: Discussionmentioning

confidence: 98%

“…[1][2][3] High dose steroids and immunosuppressives add to their susceptibility to develop sepsis. [3][4] It is important to recognize the clinical and microbial profile of sepsis in order to formulate management guidelines suitable to dermatology inpatients. Several studies have been conducted in intensive care units, burn wards, medical and surgical wards but as far as ascertained; no such study has been undertaken in the dermatology patients.…”

Section: Introductionmentioning

confidence: 99%

Clinical and bacteriological profile and outcome of sepsis in dermatology ward in tertiary care center in New Delhi

Asati¹,

Vk²,

Khandpur³

et al. 2011

Indian J Dermatol Venereol Leprol

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“…En un estudio retrospectivo de causa de mortalidad en pacientes hospitalizados por enfermedades dermatológicas entre 1995-2001; el pénfigo fue la causa más frecuente, explicando 35% de todas las causas (tasa de mortalidad global 3,58%). Todos estos pacientes tenían más de 70% de compromiso cutáneo y las causas de muerte fueron compromiso cutáneo extenso, sepsis, neumonía y alteraciones hidroelectrolíticas 17 . El diagnóstico diferencial del PV debe considerar el penfigoide buloso, la necrolísis epidérmica tóxica, el Síndrome de Steven-Johnson, otras erupciones por fármacos, quemaduras, otras variantes de pénfigo como el pénfigo por IgA y las estomatitis por quimioterapia, entre otros.…”

Section: Discussionunclassified

“…La dapsona también podría ser útil como ahorrador de corticoides. Por otra parte, la ciclosporina pareciera no tener un rol como ahorrador de corticoides 17 . Agregar pimecrolimus 1% tópico al tratamiento con prednisona y azatioprina pareciera ser efectivo 20 .…”

Section: Discussionunclassified

Pénfigo vulgar tipo cutáneo: Caso clínico

et al. 2013

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Cutaneous pemphigus vulgaris.A case report , el pénfigo paraneoplásico, el pénfigo inducido por drogas 1 y el pénfigo por IgA. El PV se puede desarrollar a cualquier edad pero es más frecuente entra la cuarta y sexta década de vida. No tiene diferencias por sexo 4 y se encontraría con mayor prevalencia en las personas con ascendencia mediterránea 1 o judía 5. La enfermedad se inicia habitualmente con úlceras orales dolorosas que no curan 6 , a diferencia de las virales o de la estomatitis aftosa, que curan en días o semanas 1 . Rara vez se encuentran ampollas en las mucosas debido a que se rompen precozmente. Las úlceras son múltiples, superficiales e irregulares y se originan en mucosas sanas. Las mucosas más comúnmente comprometidas son la labial, palatina y de la lengua. Por esta razón, el diagnóstico de pénfigo debe considerarse en toda úlcera que no cure en un período mayor a un mes 1 . Luego de semanas a meses, comienza el compromiso cutáneo, inicialmente en cuero cabelludo, cara y tórax superior pudiendo acompañarse de síntomas de compromiso nasal y esofágico. La enfermedad puede también comprometer la región periungueal 1 . Las lesiones cutáneas se originan en piel sana, inicialmente como ampollas flácidas, que se rompen durante los primeros días transformándose en erosiones superficiales con un collarete de epidermis laxa alrededor 1 . El PV activo -y en sus formas más severas-, presenta signo de Nikolsky positivo en piel sana y perilesional.

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A study of mortality in dermatology

Abstract: Area of skin involvement, electrolyte imbalance and septicemia were important factors leading to death in pemphigus and toxic epidermal necrolysis. We advocate that such patients should be managed in burns unit or ICU units.

Cited by 21 publications

References 3 publications

Analysis of Mortality in a Dermatological Affections Referral Center in Sub-Saharan Africa, Abidjan, République de Côte d'Ivoire

Analysis of Mortality in a Dermatological Affections Referral Center in Sub-Saharan Africa, Abidjan, République de Côte d'Ivoire

Clinical and bacteriological profile and outcome of sepsis in dermatology ward in tertiary care center in New Delhi

Pénfigo vulgar tipo cutáneo: Caso clínico

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