In order to explore a new English teaching mode, this paper constructs a hybrid teaching model of English in colleges and universities combined with multimedia to respond to the call for reform and innovation of teaching mode. Firstly, through analyzing three hybrid modes of teaching: complementary mode, flipped mode and cooperative mode, a multimedia-based hybrid English teaching model is constructed in combination with current multimedia technology. Secondly, the fuzzy comprehensive teaching evaluation model based on EWM-AHP-DEMATEL and the teaching quality and learning quality evaluation index system of the hybrid English teaching mode in the multimedia context were constructed. Then in the teaching evaluation system, it was found that the satisfaction of teaching materials construction after the improvement was only 85%. There is still a lot of room for improvement, but overall, all have more than 5% satisfaction improvement. In the learning evaluation system, the number of outstanding students in English class participation, English accompanying test, innovation challenge, and English practice all increased by more than 5, and the number of those needing efforts decreased by more than 3. The overall grade improved by about 12% compared to the previous semester. Finally, the conclusion found that this new teaching model can improve teaching ability and students’ English learning ability and is worth implementing in colleges and universities.