This study focused on fire detection factors by confirming the adaptation level of fire detection due to black smoke generated in the case of polyurethane foam fire, and it compared and analyzed the change in combustion products. An experiment was conducted to derive fire detection factors using the UL 268 polyurethane foam real fire test standard. Combustion products were measured using a particulate matter sensor (PMS), combustion gas analyzer (CGA), and gas analyzer (GA). As a result of the experiment, it was confirmed that the adaptability of the existing fire detector deteriorated when black smoke was generated. The fire detection factor was derived using the measured values of combustion products. In particular, among the measured factors, the most adaptable combustion products were found to be PM 2.5, PM 10, NO, and CO. They were considered to improve reliability when used as fire detection factors, as compared to existing fire detectors.