A study to evaluate prescribing pattern of antibiotics among patients of urinary tract infection with preexisting renal disorders in a tertiary care hospital

Dhodi, Dinesh K; Jaiswar, Sarita; Bhagat, Sagar; Gambre, Rohini S

doi:10.5455/2319-2003.ijbcp20140825

Cited by 9 publications

(13 citation statements)

References 19 publications

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“…Our results showed that UTI was more prevalent in rural areas and less prevalent in urban areas. Most of the UTI cases belong to urban area similar to the study by Dhodi et al [32]. The prevalence of UTI was varying according to geographical and regional locations.…”

Section: Discussionsupporting

confidence: 71%

Prevalence and Antibiogram of MDR E. coli Strains Isolated from UTI Patients—1-Year Retrospective Study at Nishtar Medical Hospital, Multan

Fatima

Rafiq

Iqbal

et al. 2020

SN Compr. Clin. Med.

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MDR uropathogens lead to high-level morbidity and mortality and pose a tremendous threat towards treatment failure and survival of UTI patients. This study was conducted to evaluate the demographic characteristics, antibiogram, and resistance pattern of Escherichia coli against antibiotics-a retrospective study at Nishtar Medical Hospital in Multan, from June 2016 to July 2017. A total of 150 clinical samples were collected and biochemically characterized by Berge's manual, and antimicrobial susceptibility testing was performed by using the Kirby-Bauer disc diffusion method and the results were interpreted according to Clinical and Laboratory Standards Institute standards. Data was analyzed by the XL-stat software. Results indicate that UTI was more prevalent in rural areas such as Alipur (28.6%) and Jalalpur (18%) and less common in urban areas like Muzaffargarh (2.66) and Multan (2%). A total of 150 patients were examined, of which 88 were females and 62 males in which more frequently found pathogens were E. coli (33%) and others Klebsiella pneumonia (18%), Proteus (10%), Staphylococcus saprophyticus (8.66%), Staphylococcus aureus (7.33%), Pseudomonas aeruginosa (6.66%), Enterobacter (6%), Candida (5.33%), and Citrobacter (4.66%). The antimicrobial susceptibility testing was carried out against E. coli strains that showed the highest overall resistance patterns of imipenem (IMI), Cip, Aug, Cfm, and CN, which were 80%, 72%, 68%, 60%, and 52%, respectively. MDR E. coli strains showed the highest resistance pattern towards IMI which put through alarming situation in Pakistan. Significant results showed that TZP, AK, and F were found sensitive in vitro against E. coli isolates of UTIs. Prevalence of MDR uropathogens near around Multan has been first time documented in this study with respect to possible risk factors associated with UTI. These alarming signs of MDR E. coli have been rarely addressed and warrant attention on urgent basis.

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Section: Discussionsupporting

confidence: 71%

Prevalence and Antibiogram of MDR E. coli Strains Isolated from UTI Patients—1-Year Retrospective Study at Nishtar Medical Hospital, Multan

Fatima

Rafiq

Iqbal

et al. 2020

SN Compr. Clin. Med.

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“…A total of 150 prescriptions were analysed, among which female were 66.67% and male were 33.33%. This female preponderance was also seen in a study conducted by Dhodi et al 10 . The reason behind this high prevalence of UTI in females is due to close proximity of the urethral meatus to the anus, shorter urethra, sexual intercourse, incontinence and bad toilet.…”

Section: Discussionsupporting

confidence: 82%

“…They are mostly treated empirically and the criteria for the selection of antimicrobial agents should be determined on the basis of the most likely pathogen and its expected resistance pattern in the locality. [10][11][12] We assessed the pattern of drugs prescribed, age and gender distribution and the most common antibiotics used.…”

Section: Discussionmentioning

confidence: 99%

Prescribing Pattern of Antimicrobials in Urinary Tract Infection at Outpatient Department in a Tertiary Care Hospital in Dhaka

Khatun

Shaha

2020

J Enam Med Col

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Background: Urinary tract infection (UTI) is the most common illness affecting both males and females in almost all age groups. Hence, continuous analysis of prescribing pattern in UTI is vital. Objective: The study was designed to determine the prescribing pattern of antibiotics in UTI patients at a tertiary care hospital. Materials and Methods: A prospective observational study was carried out on 180 patients in Dhaka National Medical College Hospital from January to March 2012 by collecting data from outpatient department of Surgery, Medicine and Gynaecology & Obstetrics. Results: Analysis of prescribed drugs revealed that use of antibiotics such as nitrofurantoin (30.55%), cefuroxime (22.22%) and ciprofloxacin (16.66%) were significantly higher compared to other drugs. The most common isolated organisms were Escherichia coli (60%), Proteus (20%), Klebsiella (13.33%), and Pseudomonas (6.66%). Conclusion: Present findings are suggestive of the need for periodic monitoring of antibiotic sensitivity pattern to provide effective treatment. J Enam Med Col 2020; 10(1): 23-26

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“…In contrast, the study conducted by Prakash and Saxena (males v.s females: 35.14% vs. 73.57%) showed the opposite. 17 UTI was most commonly witnessed in both the genders in the age group of 60-65 years, whereas in the study carried out by Dinesh and his team, 13 UTI was more common in females of age group 31-45 years. 17,18 This difference might be because our study was conducted in geriatric populations whose comorbidities such as diabetes mellitus and increasing risk of age related prostate disorders increased its incidence.…”

Section: Discussionmentioning

confidence: 60%

Urinary Tract Infection Treatment Pattern of Elderly Patients in a Tertiary Hospital Setup in South India: A Prospective Study

Ramanath¹,

Prabhu

Nandakumar

et al. 2016

JYP

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Introduction: Urinary tract infections (UTIs) are more common in geriatrics due to physiological alterations/pathological conditions. The main objective of this study was to analyze the incidence, causative organisms, types of antibiotics used, drug interactions, the antibiotic cost, and its outcome. Method: This is across-sectional study conducted in selected medicine units over a period of 18 months. The enrolled patient's therapy pattern spotted from the admission to discharge. The mandatory patients provided with pharmaceutical care services. Results: Among 475 observed cases, 106 patients had UTIs (22.31%). The mean number of drug were 7.42 ± 2.31per prescription. Out of 106 prescriptions, 63 prescriptions had drug interactions. The drug interactions degree varied from mild (12.63%), moderate (60.3%) and severe (26.58%) remained managed by spacing intervals, alternate drug use, and close monitoring techniques. Strangely, all comorbid UTI patient outcomes showed improvement. The antibiotic cost of the management ranged from $ 0.21-160.8 with a median of $ 26.30 and the common organisms were E. coli (48%), Enterococcus (16%). The average length of patient hospital stay was 11.65 ± 8.94 days. Conclusion: This study showed that about one-fourth patients have UTIs and half of them were affected by E. coli. Hence, this study proposes the paucity and its implication of pharmaceutical care service research studies, on healthhygiene, proper use of antibiotics & its cost minimization; untoward interactions cost prevention, for better outcome in India.

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A study to evaluate prescribing pattern of antibiotics among patients of urinary tract infection with preexisting renal disorders in a tertiary care hospital

Cited by 9 publications

References 19 publications

Prevalence and Antibiogram of MDR E. coli Strains Isolated from UTI Patients—1-Year Retrospective Study at Nishtar Medical Hospital, Multan

Prevalence and Antibiogram of MDR E. coli Strains Isolated from UTI Patients—1-Year Retrospective Study at Nishtar Medical Hospital, Multan

Prescribing Pattern of Antimicrobials in Urinary Tract Infection at Outpatient Department in a Tertiary Care Hospital in Dhaka

Urinary Tract Infection Treatment Pattern of Elderly Patients in a Tertiary Hospital Setup in South India: A Prospective Study

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