A universal signal-on electrochemical assay for rapid on-site quantitation of vibrio parahaemolyticus using aptamer modified magnetic metal–organic framework and phenylboronic acid-ferrocene co-immobilized nanolabel

Wang, Wenhai; Tan, Lei; Wu, Jiayi; Li, Tianhua; Xie, Hongzhen; Wu, Dazhen; Gan, Ning

doi:10.1016/j.aca.2020.08.006

Cited by 44 publications

(13 citation statements)

References 39 publications

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“…MNPs connected with recognition receptors can initially absorb analytes in the liquid phase, and then they can be quantified on the solid (electrode)–liquid (electrolyte) electrode surface by electrochemical method. MNPs as nanocarriers for MIP materials have been frequently reported (Wenhai Wang et al., 2020). MIP can form a thin layer coated on the surface of MNPs with a core–shell structure by surface molecular imprinted technology.…”

Section: Flexible Sensing Strategies Based On Nanomaterialsmentioning

confidence: 99%

Recent advances in nanomaterial‐assisted electrochemical sensors for food safety analysis

Ren

et al. 2022

Food Frontiers

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Food safety as a public health issue has aroused worldwide concern. Food safety risks caused by the existence of food safety hazards in food may occur in all stages of the food supply chain. Thus, great emphasis is placed on sensitive, selective, and convenient analytical methods of various food safety hazards in food. At present, nanomaterials are at the forefront of various electrochemical sensing applications. Given their unique physical, chemical, and biological characteristics, nanomaterials are considered perfect candidates for the design of electrode surface to construct electrochemical sensors with excellent analytical performance. With the assistance of nanomaterials, electrochemical sensors are a potential alternative to conventional methods of food safety analysis. This review focuses on current research achievements of nanomaterial‐assisted electrochemical sensors for food safety analysis reported in recent 5 years. It highlights the different detection mechanisms for analytes, flexible sensing strategies based on nanomaterials, and portable miniaturized electrochemical devices. Finally, the challenges and limitations in the design of electrochemical sensors for food safety analysis are also discussed.

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Section: Flexible Sensing Strategies Based On Nanomaterialsmentioning

confidence: 99%

Recent advances in nanomaterial‐assisted electrochemical sensors for food safety analysis

Ren

et al. 2022

Food Frontiers

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“…The concentration ranged between 10 and 10 9 cfu/mL. Wang et al found that it is possible to achieve fast on-site assays with the use of the compact SPE with a LOD of 20 min as the measurement platform [ 128 ].…”

Section: Mof-based Electrochemical Biosensors For Biomedical Usesmentioning

confidence: 99%

A Comprehensive Review of Metal–Organic Framework: Synthesis, Characterization, and Investigation of Their Application in Electrochemical Biosensors for Biomedical Analysis

Dourandish

Tajik

Beitollahi

et al. 2022

Sensors

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Many studies have addressed electrochemical biosensors because of their simple synthesis process, adjustability, simplification, manipulation of materials’ compositions and features, and wide ranges of detection of different kinds of biomedical analytes. Performant electrochemical biosensors can be achieved by selecting materials that enable faster electron transfer, larger surface areas, very good electrocatalytic activities, and numerous sites for bioconjugation. Several studies have been conducted on the metal–organic frameworks (MOFs) as electrode modifiers for electrochemical biosensing applications because of their respective acceptable properties and effectiveness. Nonetheless, researchers face challenges in designing and preparing MOFs that exhibit higher stability, sensitivity, and selectivity to detect biomedical analytes. The present review explains the synthesis and description of MOFs, and their relative uses as biosensors in the healthcare sector by dealing with the biosensors for drugs, biomolecules, as well as biomarkers with smaller molecular weight, proteins, and infectious disease.

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“…Although mediators are not necessary in FNA biosensors, the use of mediators can help biosensors to detect analytes more sensitively or to optimize the signal generation of biosensors in some specific situations. For example, the mediator can mediate the specific binding process between the sensor and the analyte, mediate the generation of fluorescent or chemical signals, or use its unique properties to significantly increase the sensitivity and detection range of FNA biosensors [41,114]. Currently, there is a wide range of research on FNA biosensor mediators.…”

Section: Mediators In Functional Nucleic-acid Biosensorsmentioning

confidence: 99%

“…Using metal-type mediators in FNA biosensors can provide high sensitivity, high flexibility, and a wide detection range. Therefore, they have been widely used in the fields of environmental monitoring, food safety, molecular biology, and medicines [27,55,114,153].…”

Section: Metal-mediated Mediatorsmentioning

confidence: 99%

Recent Advances on Functional Nucleic-Acid Biosensors

Zhang

Guo

et al. 2021

Sensors

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In the past few decades, biosensors have been gradually developed for the rapid detection and monitoring of human diseases. Recently, functional nucleic-acid (FNA) biosensors have attracted the attention of scholars due to a series of advantages such as high stability and strong specificity, as well as the significant progress they have made in terms of biomedical applications. However, there are few reports that systematically and comprehensively summarize its working principles, classification and application. In this review, we primarily introduce functional modes of biosensors that combine functional nucleic acids with different signal output modes. In addition, the mechanisms of action of several media of the FNA biosensor are introduced. Finally, the practical application and existing problems of FNA sensors are discussed, and the future development directions and application prospects of functional nucleic acid sensors are prospected.

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A universal signal-on electrochemical assay for rapid on-site quantitation of vibrio parahaemolyticus using aptamer modified magnetic metal–organic framework and phenylboronic acid-ferrocene co-immobilized nanolabel

Cited by 44 publications

References 39 publications

Recent advances in nanomaterial‐assisted electrochemical sensors for food safety analysis

Recent advances in nanomaterial‐assisted electrochemical sensors for food safety analysis

A Comprehensive Review of Metal–Organic Framework: Synthesis, Characterization, and Investigation of Their Application in Electrochemical Biosensors for Biomedical Analysis

Recent Advances on Functional Nucleic-Acid Biosensors

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