A Vascular Growth Following Radiation Therapy for Breast Carcinoma Treatment

Baum, Sascha; Patel, Rishi; McLellan, Beth N.

doi:10.1001/jamadermatol.2013.4413

Cited by 2 publications

(2 citation statements)

References 6 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Furthermore, the effect of surgery itself was highlighted by Yoon and colleagues, who observed that the radicality of surgery was more predictive of subsequent development of AVLC than tumor stage 18 . Lastly, several recent studies also suggested radiotherapy as an etiology in the development of AVLC 31,32 . Radiation likely induces inflammatory changes and tissue fibrosis, which compromises lymphatic drainage 33 .…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Malignancy‐associated acquired vulvar lymphangioma circumscriptum: A clinicopathologic study of 71 cases

et al. 2021

View full text Add to dashboard Cite

Background Acquired lymphangioma circumscriptum of the vulva is rare and can occur subsequent to malignancies of the anogenital and pelvic region. We sought to investigate the clinicopathologic characteristics of malignancy‐associated acquired vulvar lymphangioma circumscriptum (AVLC). Methods We identified all cases of AVLC within our institution with history of prior malignancy between 2005 and 2021. A similar search was performed in the PubMed database to identify published cases to date. The clinical and histopathologic information was recorded. Results A total of 71 cases were identified. The most common preceding malignancy was cervical carcinoma (71.8%, 51/71). Radiation therapy was given to 91.4% (64/70) of the patients and lymph node dissection was made on 70.2% (40/57). Median interval between the diagnosis of malignancy and the AVLC was 10 years (range 0‐32 years). AVLC frequently presented as vesicular (31.6%, 18/57) or verrucous (28.1%, 16/57) lesions clinically. Common treatments for AVLC included excision (53.1%, 26/49) and laser therapy (16.3%, 8/49), with an overall recurrence rate of 42.9% (24/56) at a median follow‐up interval of 1.8 years (range 0.04‐32.3 years). Conclusion AVLC is a rare, late complication of anogenital and pelvic malignancies causing debilitating physical symptoms and psychological stress. Further studies are warranted to determine the most effective treatment modalities to mitigate recurrence.

show abstract

Section: Discussionmentioning

confidence: 99%

“…18 Lastly, several recent studies also suggested radiotherapy as an etiology in the development of AVLC. 31,32 Radiation likely induces inflammatory changes and tissue fibrosis, which compromises lymphatic drainage. 33 The overwhelming majority (91.4%) of patients in the current study received radiation, which seems to support this notion.…”

Section: Discussionmentioning

confidence: 99%

Malignancy‐associated acquired vulvar lymphangioma circumscriptum: A clinicopathologic study of 71 cases

et al. 2021

View full text Add to dashboard Cite

show abstract

Lymphangioma secondary to irradiation after mastectomy

Oliveti

Biasi²,

Funchal

2017

An. Bras. Dermatol.

View full text Add to dashboard Cite

Lymphangioma is a rare benign disease of the lymphatic vessels. Typically, they are primary conditions but may be acquired secondarily, such as those caused by irradiation during radiotherapy for the treatment of breast cancer. The local lymphatic obstruction provoked by irradiation causes the appearance of asymptomatic hyaline vesicles on the irradiated skin. The present report describes a 78-year-old female patient, who initially presented hyaline vesicles that progressed into multiple papules with serous exudation of a yellowish and odorless secretion on the area of chronic radiodermitis in right breast. Despite the rarity of the case, we emphasize the importance of knowledge regarding dermatological disease for early diagnosis and proper medical conduct.

show abstract

A Vascular Growth Following Radiation Therapy for Breast Carcinoma Treatment

Cited by 2 publications

References 6 publications

Malignancy‐associated acquired vulvar lymphangioma circumscriptum: A clinicopathologic study of 71 cases

Malignancy‐associated acquired vulvar lymphangioma circumscriptum: A clinicopathologic study of 71 cases

Lymphangioma secondary to irradiation after mastectomy

Contact Info

Product

Resources

About