A versatile fluorescent dye based on naphthalimide: highly selective detection of Hg<sup>2+</sup>in aqueous solution and living cells and its aggregation-induced emission behaviour

Un, Hio-Ieng; Huang, Chang‐Bo; Huang, Chusen; Jia, Ti; Zhao, Xiao‐Li; Wang, Cuihong; Xu, Lin; Yang, Hai‐Bo

doi:10.1039/c4qo00185k

Cited by 64 publications

(17 citation statements)

References 108 publications

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“…8) based on the N-butyl-4-bromo-1,8-naphthalimide moiety. The probe was employed for a fluorescence 'turn on' monitoring of Hg 2+ over a wide range of several other cations, including Zn 2+ , Mn 2+ , Ba 2+ , Ni 2+ , Cu 2+ , Co 2+ , Pb 2+ , Mg 2+ , Cd 2+ , Fe 2+ , Al 3+ , Ag + , Na + , and Li + (Un et al 2014). In aqueous solution (THF-H 2 O, 1:1, pH = 7.4, 10 mM Tris-HCl), Hg 2+ addition to a solution of Hg-5 induced a notable enhancement of fluorescence.…”

Section: Small-molecule Hg 2+ Probes Based On Naphthalimide Fluorophorementioning

confidence: 99%

Fluorescent, colourimetric, and ratiometric probes based on diverse fluorophore motifs for mercuric(II) ion (Hg2+) sensing: highlights from 2011 to 2019

Aderinto

2020

Chem. Pap.

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Though it has not been shown to deliver any biological importance, mercuric(II) ion (Hg 2+) is a deleterious cation which poses grievous effects to the human body and/or the ecosystem, hence, the need for its sensitive and selective monitoring in both environmental and biological systems. Over the years, there has been a great deal of work in the use of fluorescent, colourimetric, and/or ratiometric probes for Hg 2+ recognition. Essentially, the purpose of this review article is to give an overview of the advances made in the constructions of such probes based on the works reported in the period from 2011 to 2019. Discussion in this review work has been tailored to the kinds of fluorophore scaffolds used for the constructions of the probes reported. Selected examples of probes under each fluorophore subcategory were discussed with mentions of the typically determined parameters in an analytical sensing operation, including modulation in fluorescence intensity, optimal pH, detection limit, and association constant. The environmental and biological application ends of the probes were also touched where necessary. Important generalisations and conclusions were given at the end of the review. This review article highlights 196 references. Keywords Mercuric(II) ion (Hg 2+) • Fluorescent probes • Colourimetric probes • Ratiometric probes • Hg 2+-selective probes • Sensing

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Section: Small-molecule Hg 2+ Probes Based On Naphthalimide Fluorophorementioning

confidence: 99%

Fluorescent, colourimetric, and ratiometric probes based on diverse fluorophore motifs for mercuric(II) ion (Hg2+) sensing: highlights from 2011 to 2019

Aderinto

2020

Chem. Pap.

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“…Due to the long‐wavelength the fluorescent probe possesses several merits, such as more obvious color change, better tissue penetration, and minimum interference from background auto‐fluorescence by biomolecules, therefore it has attracted intense interest of researchers. So far, numerous colorimetric or fluorescent probes for detecting Hg 2+ have been synthesized and reported; however, some shortcomings still existed in most of them, such as bad water solubility, color/fluorescence quenching, and short‐wavelength . Hence, simple long‐wavelength fluorophores (> 600 nm) with excellent fluorescence‐on property are still in high demand.…”

Section: Introductionmentioning

confidence: 99%

A highly selective colorimetric and long‐wavelength fluorescent probe for the detection of Hg²⁺

Wang

Liu

et al. 2018

Luminescence

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Currently, the fluorescent probe is an important method for detecting heavy metal ions, especially mercury ion (Hg ), which is harmful to the health of humans and the environment due to its toxicity and extensive use. In this paper, we designed and synthesized a colorimetric and long-wavelength fluorescent probe Hg-P with high sensitivity and excellent selectivity, which could detect Hg by the changes of visual color, fluorescence and absorption spectroscopy. With the addition of Hg to probe Hg-P solution, its color changed from yellow to pink, and showed a 171 nm red-shifted absorption spectrum. Probe Hg-P was used in real water and soil solution samples to detect Hg , and the result is satisfactory. Therefore, this new probe shows great value and application in detecting Hg in the environment.

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“…A number of elegant methods have been developed for the sensitive and selective detection of cells and intracellular species [1][2][3][4][5][6][7]. Among them, electrochemistry, because of its sensitivity and simplicity, has received much interest in the construction of biosensors for cell detection [8][9][10][11].…”

Section: Introductionmentioning

confidence: 99%

“Clicked” galactosyl anthraquinone on graphene electrodes for the label-free impedance detection of live cancer cells

Cui

Zhu

et al. 2015

Dyes and Pigments

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A versatile fluorescent dye based on naphthalimide: highly selective detection of Hg²⁺in aqueous solution and living cells and its aggregation-induced emission behaviour

Abstract: A simple and versatile fluorescent dye NPS based on 1,8-naphthalimide was successfully designed and prepared. It was found that NPS exhibited excellent selectivity for Hg 2+ over many other metal ions

Cited by 64 publications

References 108 publications

Fluorescent, colourimetric, and ratiometric probes based on diverse fluorophore motifs for mercuric(II) ion (Hg2+) sensing: highlights from 2011 to 2019

Fluorescent, colourimetric, and ratiometric probes based on diverse fluorophore motifs for mercuric(II) ion (Hg2+) sensing: highlights from 2011 to 2019

A highly selective colorimetric and long‐wavelength fluorescent probe for the detection of Hg²⁺

“Clicked” galactosyl anthraquinone on graphene electrodes for the label-free impedance detection of live cancer cells

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A versatile fluorescent dye based on naphthalimide: highly selective detection of Hg2+in aqueous solution and living cells and its aggregation-induced emission behaviour

Abstract: A simple and versatile fluorescent dye NPS based on 1,8-naphthalimide was successfully designed and prepared. It was found that NPS exhibited excellent selectivity for Hg 2+ over many other metal ions

Cited by 64 publications

References 108 publications

Fluorescent, colourimetric, and ratiometric probes based on diverse fluorophore motifs for mercuric(II) ion (Hg2+) sensing: highlights from 2011 to 2019

Fluorescent, colourimetric, and ratiometric probes based on diverse fluorophore motifs for mercuric(II) ion (Hg2+) sensing: highlights from 2011 to 2019

A highly selective colorimetric and long‐wavelength fluorescent probe for the detection of Hg2+

“Clicked” galactosyl anthraquinone on graphene electrodes for the label-free impedance detection of live cancer cells

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Product

Resources

About

A versatile fluorescent dye based on naphthalimide: highly selective detection of Hg²⁺in aqueous solution and living cells and its aggregation-induced emission behaviour

A highly selective colorimetric and long‐wavelength fluorescent probe for the detection of Hg²⁺