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Abstract

One of the most developed pharmaceutical preparations for paracetamol is a syrup. An important additional substance required in the formulation of the syrup is a coloring agent. Telang flower (Clitoria ternatea) is one of the plants that has been proved to contain anthocyanins. Anthocyanin is a compound which can be used as a coloring agent. Thus, it is important to further explore telang flower's potential as a natural coloring agent in paracetamol syrup preparation. This research was started with the extraction of the dye or anthocyanin content in the telang flower. The extraction was performed by ethanol with maceration method. Paracetamol syrups were prepared in four different formulations (F1, F2, F3, and F4). F1, F2, and F3 contained three increased concentrations of telang extract of 0.25%, 0.5% and 1.0%, respectively, while F4 was added with the synthetic food coloring agent, as a control. Each formula was evaluated based on its physical properties parameters including organoleptic observation, pH, density viscosity, and color stability test using spectrophotometry. The results of organoleptic, pH, density viscosity, and color stability parameters showed that telang extract with the concentration of 0.25% and 1% possessed more stable result than 0,5% concentration in the paracetamol syrup preparations.

Effect of trehalose and butterfly pea (Clitoris ternatea L.) on physicochemical characteristics of drum dried milk powder

“…The amount of Butterfly Pea powder used impacts the color of the Butterfly Pea powder milk generated; the more Butterfly Pea powder added, the bluer the color of the Butterfly Pea powder milk produced. This statement is consistent with the findings of Pratimasari & Lindawati (2018), who discovered that the color of paracetamol syrup dyed with Butterfly Pea varies from light purple to dark purple, and that the higher the concentration of Butterfly Pea added to the syrup, the more intense the color intensity produced.…”

Pemberdayaan Kader PKK dalam Pengenalan dan Pembuatan Minuman Sirup Kombinasi Bunga Telang dan Rempah di Kelurahan Kauman Kota Malang

“…Jumlah penderita di Kelurahan Kauman ditahun 2018 untuk penyakit diabetes melitus sebesar 69%, sedangkan hipertensi sebesar 46%; di tahun 2019 jumlah penderita diabetes melitus 79% dan jumlah penderita hipertensi 51%, sedangkan di tahun 2020 jumlah penderita diabetes melitus 100% dan jumlah hipertensi 20% (Anisyah et al, 2022). Sirup merupakan sediaan farmasetik dalam bentuk larutan, digunakan secara oral yang mempunyai komposisi gula dengan kadar 64-66% dan memudahkan bagi pasien yang ada kesulitan untuk menelan (Pratimasari & Lindawati, 2018). Menurut hasil penelitian (Fitri et al, 2017), bahwa sirup dapat dikatakan juga suatu sediaan minuman berupa larutan kental, mempunyai rasa beranekaragam serta harus diencerkan terlebih dahulu sebelum diminum.…”