Abdominal volume index trajectories and risk of diabetes mellitus: Results from the China Health and Nutrition Survey

Abstract

Aims/Introduction Abdominal obesity is a risk factor for developing diabetes mellitus, but trajectories of abdominal obesity over time and incident diabetes mellitus have not been considered. We derived trajectories of abdominal volume index (AVI) over 16 years of follow up, and examined the associations between AVI trajectories and risk of diabetes mellitus. Materials and Methods Data were used from the China Health and Nutrition Survey, and 5,267 participants were enrolled to fit the trajectory of AVI by using latent class growth models. Multivariate logistic regression models explored the relationship between different AVI trajectories and risk of diabetes mellitus. In addition, we examined the slope of the AVI trajectories in relation to age to identify appropriate life course intervention opportunities for the prevention of diabetes mellitus. Results Three trajectories were derived reflecting graded categories in the speed and slope of increase in AVI over time: slow, intermediate and fast increase group, respectively. After multivariate adjustment, the odds ratios for diabetes mellitus among those in the intermediate and fast increase groups were 1.81 (95% confidence interval 1.37–2.38, P < 0.001) and 2.80 (95% confidence interval 1.85–4.24, P < 0.001) respectively, relative to the slow increase group. The distribution of AVI slope in the slow increase group showed an inverted "U" shape, whereas the fast increase group presented a "U" shape. Conclusions AVI trajectory is associated with an increased risk of diabetes mellitus. These results provide new insights on the relationship between abdominal adiposity and diabetes mellitus, which in turn can help improve clinical and public health intervention for diabetes mellitus prevention.

The role of remnant cholesterol beyond low-density lipoprotein cholesterol in diabetes mellitus

“…The China Health and Nutrition Survey (CHNS) is an ongoing longitudinal community-based cohort study carried out by the national and local governments of China, and the study details were described in our previous article [25]with the relevant protocol published elsewhere [26]. The CHNS is a collaborative project between the Carolina Population Center, University of North Carolina at Chapel Hill and the National Institute for Nutrition and Health (NINH, former National Institute of Nutrition and Food Safety), Chinese Center for Disease Control and Prevention.…”

Do macronutrient intakes affect obesity indices in Jordanian adults?

“…However, their association with dietary consumption has not received much attention. Hu and coworkers discovered that a higher AVI was associated with higher energy intake when they calculated AVI trajectories over the course of 16 years of follow‐up and examined the associations between these trajectories and the risk of diabetes mellitus (Hu et al, 2022). Similarly, do Prado et al, reported that the consumption of ultra‐processed food was one of the primary causes of CI elevation and that CI had strong discriminatory power for the diagnosis of abdominal obesity among rural workers (do Prado et al, 2022).…”

Novel Anthropometric Indices as Screening Tools for Obesity: A Study on Healthy Iranians

“…For predicting metabolic syndrome in a similar study by Duan et al, AVI had the AUC of 0.838 and 0.794 for men and women, respectively [ 50 ]. In a study by Hu et al, AVI, as an index for abdominal adiposity, was associated with diabetes mellitus [ 29 ]. In a study by Hajian-Tilaki et al, they demonstrated that AVI and WC had the same mean between males and females, while the means of BMI and WHtR were different between the two groups.…”

“…Abdominal volume index (AVI) is another novel anthropometric index and indicator of central obesity that is shown to be correlated with diabetes mellitus and metabolic abnormalities [26][27][28]. AVI has been suggested as a screening tool for metabolic syndrome of adulthood in diferent populations [29,30].…”