Abnormal diurnal weight gain among long-term patients with schizophrenic disorders

Vieweg, W. Victor R.; Godleski, Linda; Graham, Peter M.; Barber, Jack W.; Goldman, F.; Kellogg, Elizabeth; Bayliss, E. V.; Glick, J. L.; Hundley, P. L.; Yank, G. R.

doi:10.1016/0920-9964(88)90042-4

Cited by 32 publications

(8 citation statements)

References 23 publications

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“…Because the measuring device was consistent during the study periods, diurnal weight change as well as different time of measurement was regarded as the main source of within-subject measurement variation, whose range was known to be ±0.5 % in the normal population [16][17][18]. When the diurnal weight change range of ±0.5 % was assumed among our participants, 62 patients (8.6 % of a total of 719 patients) with DW 1 m from 2.5 to 3.5 % might have the risk of being misclassified because of measurement error.…”

Section: Discussionmentioning

confidence: 99%

Weight loss at the first month of palliative chemotherapy predicts survival outcomes in patients with advanced gastric cancer

Ock

Lee

et al. 2015

Gastric Cancer

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Background Weight loss during chemotherapy is a significant prognostic factor for poor survival in patients with advanced gastric cancer (AGC). However, in most studies, weight loss was measured at the end of chemotherapy, limiting its clinical use. In this study, we evaluated whether weight loss during the first month of chemotherapy could predict survival outcomes in patients with AGC. Methods We analyzed 719 patients with metastatic or recurrent AGC who were receiving palliative chemotherapy. We calculated the initial body mass index (BMIi), percent weight loss after 1 month of chemotherapy (DW 1 m), percent weight loss after last administration of chemotherapy (DW end ), and average weight loss per month during chemotherapy (DW/m). We correlated these data with overall survival (OS) by receiver-operating characteristic (ROC) curves and Kaplan-Meier curves, and performed a subgroup analysis using Cox regression. Results The probabilities of longer OS had stronger correlations with DW/m and DW 1 m than with DW end or BMIi. A significant positive correlation between DW 1 m and DW/ m (r 2 = 0.591, p \ 0.001) was observed.

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Section: Discussionmentioning

confidence: 99%

Weight loss at the first month of palliative chemotherapy predicts survival outcomes in patients with advanced gastric cancer

Ock

Lee

et al. 2015

Gastric Cancer

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“…Lithium treatment may cause weight gain in humans (1) and alter circadian cycles of body weight in rats (2). Recently, we reported that diurnal weight gain is abnormal among chronically psychotic patients (3,4). Now, we report that lithium treatment independent of polyuria (hence, polydipsia) does not cause abnormal diurnal weight gain among institutionalized chronically psychotic patients.…”

mentioning

confidence: 66%

Lithium, polyuria and abnormal diurnal weight gain in psychosis

Vieweg

Godleski

Hundley

et al. 1988

Acta Psychiatr Scand

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We evaluated diurnal weight gain and polyuria among 31 institutionalized chronically psychotic patients receiving lithium and 42 controls not receiving this drug. The patients were weighed weekly for three weeks at 7 a.m. and 4 p.m. We normalized the diurnal weight gain (NDWG) as a percentage by subtracting the 7 a.m. weight from the 4 p.m. weight, multiplying the difference by 100, and then dividing the result by the 7 a.m. weight. Polyuria was assessed using mean urine creatinine concentration (MUCR). NDWG was abnormal among study patients (1.9 +/- 1.2%) and controls (1.6 +/- 1.5%) independent of lithium treatment. The variation in MUCR explained about 20% of the variation in NDWG in both groups.

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“…In case 1, we measured only midday body weights as a reflection of polydipsia. Documenting normalized diurnal weight gain (NDWG) [16] or percent of maximum weight gain (PMWG) may be superior methods [17]. Since sixty-three separate weights were recorded, our findings still suggest that the patient had a net reduction in intake.…”

Section: Discussionmentioning

confidence: 87%