Acoustoelectric imaging for beat-to-beat cardiac activation wave mapping in an in vivo swine model

Alvarez, Alexander; Preston, Chet; Trujillo, Teodoro; Witte, Russell S.

doi:10.1109/ius46767.2020.9251637

Cited by 1 publication

(1 citation statement)

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“…In addition, he used UCSDI for the first time to map the anatomical potential conduction of the living rabbit heart, which could provide the spatiotemporal distribution of cardiac activation waves (Olafsson et al, 2009 ). Alvarez later demonstrated current source imaging in vivo for the first time in a swine model (Alvarez et al, 2019 , 2020a , b ). Wang also used a pair of electrodes to generate alternating current distributions in a special imaging chamber filled with 0.9% NaCl solution, and obtained time-lapse volume movies of the alternating current distribution ( Figure 5 ) (Wang et al, 2011 ).…”

Section: Research Progressmentioning

confidence: 99%

Biological current source imaging method based on acoustoelectric effect: A systematic review

Zhang

Liu

et al. 2022

Front. Neurosci.

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Neuroimaging can help reveal the spatial and temporal diversity of neural activity, which is of utmost importance for understanding the brain. However, conventional non-invasive neuroimaging methods do not have the advantage of high temporal and spatial resolution, which greatly hinders clinical and basic research. The acoustoelectric (AE) effect is a fundamental physical phenomenon based on the change of dielectric conductivity that has recently received much attention in the field of biomedical imaging. Based on the AE effect, a new imaging method for the biological current source has been proposed, combining the advantages of high temporal resolution of electrical measurements and high spatial resolution of focused ultrasound. This paper first describes the mechanism of the AE effect and the principle of the current source imaging method based on the AE effect. The second part summarizes the research progress of this current source imaging method in brain neurons, guided brain therapy, and heart. Finally, we discuss the problems and future directions of this biological current source imaging method. This review explores the relevant research literature and provides an informative reference for this potential non-invasive neuroimaging method.

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