The large volume of high-resolution images acquired by the Mars Reconnaissance Orbiter has opened a new frontier for developing automated approaches to detecting landforms on the surface of Mars. However, most landform classifiers focus on crater detection, which represents only one of many geological landforms of scientific interest. In this work, we use Convolutional Neural Networks (ConvNets) to detect both volcanic rootless cones and transverse aeolian ridges. Our system, named MarsNet, consists of five networks, each of which is trained to detect landforms of different sizes. We compare our detection algorithm with a widely used method for image recognition, Support Vector Machines (SVMs) using Histogram of Oriented Gradients (HOG) features. We show that ConvNets can detect a wide range of landforms and has better accuracy and recall in testing data than traditional classifiers based on SVMs.
Objective. New innovations in deep brain stimulation (DBS) enable directional current steering—allowing more precise electrical stimulation of the targeted brain structures for Parkinson’s disease, essential tremor and other neurological disorders. While intra-operative navigation through MRI or CT approaches millimeter accuracy for placing the DBS leads, no existing modality provides feedback of the currents as they spread from the contacts through the brain tissue. In this study, we investigate transcranial acoustoelectric imaging (tAEI) as a new modality to non-invasively image and characterize current produced from a directional DBS lead. tAEI uses ultrasound (US) to modulate tissue resistivity to generate detectable voltage signals proportional to the local currents. Approach. An 8-channel directional DBS lead (Infinity 6172ANS, Abbott Inc) was inserted inside three adult human skulls submerged in 0.9% NaCl. A 2.5 MHz linear array delivered US pulses through the transtemporal window and focused near the contacts on the lead, while a custom amplifier and acquisition system recorded the acoustoelectric (AE) interaction used to generate images. Main results. tAEI detected monopolar current with stimulation pulses as short as 100 µs with an SNR ranging from 10–27 dB when using safe US pressure (mechanical indices <0.78) and injected current of ~2 mA peak amplitude. Adjacent contacts were discernable along the length and within each ring of the lead with a mean radial separation between contacts of 2.10 and 1.34 mm, respectively. Significance. These results demonstrate the feasibility of tAEI for high resolution mapping of directional DBS currents using clinically-relevant stimulation parameters. This new modality may improve the accuracy for placing the DBS leads, guide calibration and programming, and monitor long-term performance of DBS for treatment of Parkinson’s disease.
Acoustoelectric cardiac imaging (ACI) is a hybrid modality that exploits the interaction of an ultrasonic pressure wave and the resistivity of tissue to map current densities in the heart. This study demonstrates for the first time in vivo ACI in a swine model. ACI measured beat-to-beat variability (n = 20) of the peak of the cardiac activation wave at one location of the left ventricle as 5.32 ± 0.74 ~V, 3.26 ± 0.54 mm below the epicardial surface, and 2.67 ± 0.56 ms before the peak of the local electrogram. Cross-sectional ACI images exhibited propagation velocities of 0.192 ± 0.061 m/s along the epicardial-endocardial axis with an SNR of 24.9 dB. This study demonstrates beat-to-beat and multidimensional ACI, which might reveal important information to help guide electroanatomic mapping procedures during ablation therapy.
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