Acremonidin E produced by Penicillium sp. SNF123, a fungal endophyte of Panax ginseng, has antimelanogenic activities

Deoxyvasicinone with Anti-Melanogenic Activity from Marine-Derived Streptomyces sp. CNQ-617

“…Melanin is synthesized in the melanosomes of melanocytes, which is transferred to neighboring keratinocytes through dendrites [17,18]. The anti-melanogenic effects of…”

“…Melanin is synthesized in the melanosomes of melanocytes, which is transferred to neighboring keratinocytes through dendrites [17,18]. The anti-melanogenic effects of deoxyvasicinone treatment were assessed in the co-culture of MNT-1 and HaCaT, human keratinocyte cell lines.…”

“…The annealing temperature of the experiment was 50 • C. 4.9. Skin Whitening Assay Using the Artificial Human Epidermal 3D Skin Model, Melanoderm TM Melanoderm TM (MaTek, Ashland, MA, USA) is a pigmented human epidermis skin model that consists of normal human-derived epidermal keratinocytes and normal humanderived melanocytes [17]. The Melanoderm TM skin was pre-incubated for 24 h, then treated with deoxyvasicinone or 1% kojic acid every other day for 10 days.…”

Metabolites of medicine food homology-derived endophytic fungi and their activities

“…(51.16%), Proteus vulgaris (15.44%), Pseudomonas aeruginosa (30.25%) The AP5-EtOAc extract ( 112 ) Fungal Extractives Anti-microbial Abdelgawad et al (2022) Candida albicans (40.14%) The AP5-EtOAc extract ( 112 ) Fungal Extractives Anti-microbial Colletotrichum coccodes Houttuynia cordata Candida albicans (125 μg/mL), Staphylococcus aureus (125 μg/mL), Escherichia coli (125 μg/mL), Pseudomonas aeruginosa (250 μg/mL) The EtOAc extract of Colletotrichum coccodes ( 113 ) Fungal Extractives Anti-microbial ( Talukdar et al, 2021 ; Talukdar et al, 2021 ) Staphylococcus aureus (19 mm) , Escherichia coli (19 mm) , Pseudomonas aeruginosa (18 mm) , Candida albicans (21 mm) The EtOAc extract of Colletotrichum coccodes ( 114 ) Fungal Extractives Anti-microbial Phyllosticta capitalensis Houttuynia cordata Staphylococcus aureus (23 mm) , Escherichia coli (14 mm) , Pseudomonas aeruginosa (14 mm) , Candida albicans (22 mm) The EtOAc extract of Phyllosticta capitalensis ( 115 ) Fungal Extractives Anti-microbial Talukdar et al (2021) Penicillium sp. SNF123 Panax ginseng B16F10, MNT-1 (2.5–50 μg/mL) Acremonidin E ( 116 ) Fungal Extractives Anti-cancer Kim et al (2019) Aspergillus terreus Glycine max Anti- COVID-19 Aspergillide B1 ( 117 ), 3a-Hydroxy-3, 5-dihydromonacolin L ( 118 ) Fungal Extractives Anti-microbial El-Hawary et al (2021) Penicillium griseofulvum MPR1 Mentha pulegium Escherichia coli (45.5 mm) The EtOAc extract of Penicillium griseofulvum MPR1 ( 119 ) …”

Discovery of a potent angiotensin converting enzyme 2 inhibitor from Chinese Medicinal and Edible Plant via Docking-based Virtual Screening

“…Ginseng is one of the most commonly used traditional medicines in China, korea, Japan, and other Asian countries, shows various biological effects including anticancer, antioxidative, antiaging, neurovascular modulatory, antiviral, and other activities [26][27][28][29]. Ginsenoside Rg6 and ginsenoside F1 show antitumor, antioxidant and anti-in ammatory effects in vitro [30][31][32][33]. Previous study has reported that ginsenoside Rb1 exerted inhibitory activity against ACE [34].…”