Action of palmatine on Tetrahymena thermophila BF5 growth investigated by microcalorimetry

Antifungal evaluation of cholic acid and its derivatives on Candida albicans by microcalorimetry and chemometrics

“…An alternative non-invasive and non-destructive approaches microcalorimetry has been paid attention widely, which allows analysis to be performed directly on a test substance, regardless of its homogeneous or heterogeneous nature, and has been extensively used as a method for rapid bioassay procedures [16][17][18][19][20]. Besides the good sensitivity, accuracy and reproducibility, microcalorimetry has some peculiar advantages in new drug discovery and response for the antifungal challenge, for example, the homogeneous system is not necessary; continuous, realtime, quantitative detection can be realized so as to obtain abundant thermo-kinetic/dynamic information or quantitative structure-activity relationship, even the information about the mechanism of action of the antifungal drugs [21,22].…”

Comparative study of effects of two bile acid derivatives on Staphylococcus aureus by multiple analytical methods

“…Microcalorimetry, a non-invasive and non-destructive technique, has long been used to study the antimicrobial activities of drug and other materials [25][26][27][28][29]. It permits the online test of bioactivity screening and can obtain a lot of important information about the process of cell growth, which cannot be obtained by the other techniques [21][22][23].…”

Acute Toxicity of Heavy Metals to Tetrahymena in an In Vitro Experiment and Envelope Damage Study

“…They are distributed widely, and perform key functions in energy flow and elementary cycling in freshwater ecosystems (Twagilimana et al 1998). Therefore, Tetrahymena is well suited for toxicological study in the environmental field, and has been used to detect water quality (Kong et al 2009;Li et al 2010).…”