1984
DOI: 10.2307/1590272
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Active and Passive Immunization of Ducks against Duck Viral Enteritis

Abstract: The newly isolated Sheridan-83 strain of duck enteritis virus (DEV) was apathogenic to ducks. Inoculation of ducks with this virus resulted in the production of antibodies that enabled the ducks to resist challenge with the virulent LA strain of DEV. The minimum protective dose of the Sheridan-83 virus was determined to be less than 10 TCID50. Solid immunity lasted 1-2 months. Passive transfer of antibodies to susceptible ducks also significantly protected them from lethal challenge.

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Cited by 16 publications
(6 citation statements)
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“…Active immunity has been established using a modified live-virus vaccine (Jansen 1964) and inactivated tissue culture vaccine through intramuscular (I/ M) routes (Shawky & Sandhu 1997). Passive immunization to susceptible ducks provides significant protection from lethal challenge (Lin et al 1984). Viral glycoproteins gB, gD, gH/gL are capable of inducing innate as well as adaptive immune response, hence are documented by many researchers as potent and suitable vaccine agent.…”
Section: Immunitymentioning
confidence: 99%
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“…Active immunity has been established using a modified live-virus vaccine (Jansen 1964) and inactivated tissue culture vaccine through intramuscular (I/ M) routes (Shawky & Sandhu 1997). Passive immunization to susceptible ducks provides significant protection from lethal challenge (Lin et al 1984). Viral glycoproteins gB, gD, gH/gL are capable of inducing innate as well as adaptive immune response, hence are documented by many researchers as potent and suitable vaccine agent.…”
Section: Immunitymentioning
confidence: 99%
“…As it affects the entry of virus in the cell and spread in between the cells, laboratory trials are needed to explore its antiviral immune response aspect. Passive immunization also provides significant protection to susceptible ducks from lethal challenge (Lin et al 1984). Attenuated DPV vaccine containing the strain CHa as a modified live vaccine protected ducks upon subcutaneous immunization and the vaccine provided adequate and satisfactory protective systemic (IgG) as well as mucosal (IgM) immunity against DP.…”
Section: Vaccinationmentioning
confidence: 99%
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“…The epithelial cells and lymphocytes of these organs are the principal sites of virus replication (Shawky, 2000;Yuan et al, 2005). Many studies on exploring the pathogenesis of acute DEV infection have been reported (Proctor, 1976;Deng et al, 1984;Lin et al, 1984;Plummer et al, 1998;Hansen et al, 2000;Cheng et al, 2004Cheng et al, , 2005. However, a great deal remains to be learned about quantitative aspects of DEV DNA load in various tissues and its relationship with the outcome of the infection.…”
Section: Introductionmentioning
confidence: 99%
“…Clinical and laboratory tests have confirmed that the attenuated DEV vaccine is an effective biological agents for the prevention and control of DVE, and the monitoring of DEV-specific antibodies is a key to evaluate the effect of the attenuated DEV vaccine and develop the rational immunization programs [5,6]. Rapid and simple test is needed for routine field practice to monitor whether the vaccines have induced antibody to DEV.…”
Section: Introductionmentioning
confidence: 99%