Actividad bactericida de superficies de cobre frente a bacterias asociadas a infecciones nosocomiales, en un modelo in vitro de adherencia y sobrevivencia

J, Valeria Prado; M, Mario Esparza; A, Roberto Vidal; T, Claudia Durán

doi:10.4067/s0034-98872013000300002

Cited by 6 publications

(4 citation statements)

References 20 publications

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“…Prado et al showed that after 48h, MRSA, Klebsiella pneumoniae and Acinetobacter baumannii did not adhere to Cu samples, contrary to stainless steel. However, Pseudomonas aeruginosa was still able to adhere [44]. In another study, the nosocomial infection rate was studied for one year in an intensive care unit.…”

Section: The Use Of Copper As An Antimicrobial In Water Air and Hospmentioning

confidence: 99%

Biological properties of copper-doped biomaterials for orthopedic applications: A review of antibacterial, angiogenic and osteogenic aspects

et al. 2020

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Copper is an essential trace element required for human life, and is involved in several physiological mechanisms. Today researchers have found and confirmed that Cu has biological properties which are particularly useful for orthopedic biomaterials applications such as implant coatings or biodegradable filler bone substitutes. Indeed, Cu exhibits antibacterial functions, provides angiogenic ability and favors osteogenesis; these represent major key points for ideal biomaterial integration and the healing process that follows. The antibacterial performances of copper-doped biomaterials present an interesting alternative to the massive use of prophylactic antibiotics and help to limit the development of antibiotic resistance. By stimulating blood vessel growth and new bone formation, copper contributes to the improved bio-integration of biomaterials. This review describes the bio-functional advantages offered by Cu and focuses on the antibacterial, angiogenic and osteogenic properties of Cu-doped biomaterials with potential for orthopedic applications.

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Section: The Use Of Copper As An Antimicrobial In Water Air and Hospmentioning

confidence: 99%

Biological properties of copper-doped biomaterials for orthopedic applications: A review of antibacterial, angiogenic and osteogenic aspects

et al. 2020

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“…While an essential trace element in living organisms, found in more than 30 types of proteins, copper ions can also be fairly toxic through the generation of reactive hydroxyl radicals and through the depletion of sulfhydryls within cells [78, 79]. Numerous studies investigating the antimicrobial activity of copper have shown that bacteria, yeasts, and viruses are killed through contact with copper and copper alloy surfaces, showing nearly complete killing of all microbes present upon contact; however, copper surfaces are most effective as an antimicrobial when having between 50–75% copper content [80–83]. In this study, we showed between a 1–2 log reduction that was slightly dose dependent with an increased amount of copper added, observing the most bacterial reduction in biofilms formed on CuAAC resins containing 4% copper chloride (CuCl 2 ).…”

Section: Discussionmentioning

confidence: 99%

Evaluation of biofilm formation on novel copper-catalyzed azide-alkyne cycloaddition (CuAAC)-based resins for dental restoratives

et al. 2018

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“…The R-squared coefficient of determination was 63.88%, which is below the recommended limit (70%) that can be attributed to the existence of other factors that are influencing the model. Copper is the factor that has the greatest influence on the biological degradation of cyanide, since it presents an inhibitory effect [70] to carry out the biodegradation of the contaminant, while iron presents statistically significant effects on its biodegradation and is benefited when working with values of 10 mg•L −1 . On the other hand, there was no statistically significant effect when working with nickel (0, 0.75 and 1.5 mg•L −1 ), nor were there statistically significant differences between the interactions of the three metals.…”

Section: Sorption Testsmentioning

confidence: 99%

Optimization of Factors for the Biological Treatment of Free and Complexed Cyanide

2023

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Mexico is characterized as a mining country since it is the world’s main silver producer. During its extraction, wastewater (mining tailings) is generated which contains cyanide and heavy metals. The purpose of this research was to determine whether a bacterial consortium isolated from a tailings dam can use cyanide as a source of nitrogen and carbon to carry out its biodegradation. The study determined the effects of three physicochemical factors (pH, temperature and inoculum concentration) and three metals (copper, iron and nickel) on cyanide biodegradation. The results showed that the highest cyanide removals were obtained when working with a pH of 9.5, a temperature of 25 °C and 15% v/v of inoculum (88%), while the optimum values for copper, iron and nickel were 0, 7.7 and 0.46 mg·L−1, respectively, showing that copper causes an inhibitory effect (cyanide biodegradation of 68%) on the bacteria and consequently on the biological degradation of cyanide and that iron can promote the biodegradation of the pollutant by 91%.

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Actividad bactericida de superficies de cobre frente a bacterias asociadas a infecciones nosocomiales, en un modelo in vitro de adherencia y sobrevivencia

Cited by 6 publications

References 20 publications

Biological properties of copper-doped biomaterials for orthopedic applications: A review of antibacterial, angiogenic and osteogenic aspects

Biological properties of copper-doped biomaterials for orthopedic applications: A review of antibacterial, angiogenic and osteogenic aspects

Evaluation of biofilm formation on novel copper-catalyzed azide-alkyne cycloaddition (CuAAC)-based resins for dental restoratives

Optimization of Factors for the Biological Treatment of Free and Complexed Cyanide

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