Acute administration of high doses of taurine does not substantially improve high-intensity running performance and the effect on maximal accumulated oxygen deficit is unclear

Abstract

The aim of the present study was to investigate the effects of acute administration of taurine overload on time to exhaustion (TTE) of high-intensity running performance and alternative maximal accumulated oxygen deficit (MAODALT). The study design was a randomized, placebo-controlled, crossover design. Seventeen healthy male volunteers (age: 25 ± 6 years; maximal oxygen uptake: 50.5 ± 7.6 mL·kg(-1)·min(-1)) performed an incremental treadmill-running test until voluntary exhaustion to determine maximal oxygen uptake and exercise intensity at maximal oxygen uptake. Subsequently, participants completed randomly 2 bouts of supramaximal treadmill-running at 110% exercise intensity at maximal oxygen uptake until exhaustion (placebo (6 g dextrose) or taurine (6 g) supplementation), separated by 1 week. MAODALT was determined using a single supramaximal effort by summating the contribution of the phosphagen and glycolytic pathways. When comparing the results of the supramaximal trials (i.e., placebo and taurine conditions) no differences were observed for high-intensity running TTE (237.70 ± 66.00 and 277.30 ± 40.64 s; p = 0.44) and MAODALT (55.77 ± 8.22 and 55.06 ± 7.89 mL·kg(-1); p = 0.61), which seem to indicate trivial and unclear differences using the magnitude-based inferences approach, respectively. In conclusion, acute 6 g taurine supplementation before exercise did not substantially improve high-intensity running performance and showed an unclear effect on MAODALT.

Acute LED irradiation does not change the anaerobic capacity and time to exhaustion during a high-intensity running effort: a double-blind, crossover, and placebo-controlled study

“…The MAOD ALT suggested by Bertuzzi et al [9] and recently validated by Zagatto et al [12] has been used to evaluate the effects of ergogenic substances on performance and the metabolic pathways [10,11]. In the MAOD ALT protocol, the W [La , and [La − ] was observed at the 7th and 10th minutes and the area under the curve for the lactate kinetics.…”

“…Prior to the tests, a warm-up lasting 5 min was performed at 8 km h −1 . During the tests, the participants wore a safety belt attached to their chest to ensure maximal effort [10,11].…”

“…The subjects performed three visits to the laboratory and underwent a graded exercise test (GXT and two supramaximal efforts at 115 % of the intensity associated with maximal oxygen uptake [10,11]. The supramaximal efforts were performed prior to the irradiation with the LEDT or a placebo and in a randomized order [19].…”

“…Recently, some studies [9][10][11][12][13] have reported the use of blood lactate responses and the fast phase of the excess postexercise consumption to estimate the maximal accumulated oxygen deficit (i.e., a reliable [12] and most scientifically accepted procedure to assess anaerobic capacity) in a single supramaximal effort (MAOD ALT ). However, considering that the MAOD ALT is determined exclusively by the delta of the blood lactate ([ΔLa − ]) and the excess post-exercise consumption [14,15], it is plausible to assume that photobiomodulation applied before the effort could modify the MAOD ALT and enhance the time to exhaustion and other energetic parameters during a high-intensity effort.…”

“…estimated using the accumulated [La − ] during the exercise (i.e., Δ[La − ] = [La − P ] − [La − B ]), assuming an equivalent of 3 mL kg −1 of oxygen per each 1 mmol L −1 of the Δ[La − ][9][10][11][12]. The W PCR was estimated using the fast phase of excess post-exercise oxygen consumption calculated by a bi-exponential mathematical fit (Eq.…”