Acute Adolescent Menorrhagia

Claessens, E. Anne; Cowell, Carol L.

doi:10.1097/00006254-198109000-00019

Cited by 14 publications

(18 citation statements)

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“…Our finding of 25 patients (16%) with a bleeding disorder in 160 adolescent patients with menorrhagia who underwent laboratory evaluation is similar to that reported in other series [1][2][3][4][5][6][7][8]. This proportion may in fact be an underestimate of the true prevalence of bleeding disorders in adolescents with menorrhagia because many patients lacked documentation of review of systems for a bleeding disorder as well as a uniform haemostatic evaluation (including testing for VWD).…”

supporting

confidence: 83%

“…The prevalence of bleeding disorders in adults with menorrhagia has been reported to be about 15% (von Willebrand's disease [VWD], 5 -24%; platelet dysfunction, approximately 50%; single factor deficiency, 1-4%) [1][2][3][4][5]. Similar studies have been reported in adolescent girls with menorrhagia, with the prevalence of haemostatic abnormalities identified as 10-40% in these patients [6,7].…”

mentioning

confidence: 70%

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Bleeding disorders in adolescents with menorrhagia: an institutional experience

et al. 2013

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supporting

confidence: 83%

mentioning

confidence: 70%

Bleeding disorders in adolescents with menorrhagia: an institutional experience

et al. 2013

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“…In one study, nearly 50% of adolescents presenting with "acute menorrhagia" at the time of menarche were found to have a bleeding disorder, including disorders of platelet number and function (e.g., idiopathic thrombocytopenic purpura), hematologic malignancies, and von Willebrand disease. 29 Other studies have corroborated these findings, suggesting that adolescents who present at menarche with "acute menorrhagia" or with severe anemia should be screened for bleeding disorders. [30][31][32][33][34][35] The prevalence of von Willebrand disease in the general population is approximately 1-2%, and has been shown to be considerably higher among adult women with heavy bleeding.…”

Section: Characteristics Of Menstrual Flowmentioning

confidence: 88%

Menstruation in Adolescents

Hillard

2008

Annals of the New York Academy of Sciences

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The conventional wisdom about menstruation in adolescents, perpetuated in textbooks, requires updating. Recently published national surveys and reviews of large historical databases provide information about menstruation in adolescents, including the following: (1) Girls are experiencing earlier pubertal development than previously noted, suggesting that guidelines for the evaluation of potentially pathologic precocious puberty be reassessed. (2) There are racial differences in pubertal development, with African American girls experiencing earlier signs than Caucasian girls, and Mexican American girls intermediate in pace. (3) The absence of pubertal development by age 14 is associated with a high probability of conditions with impaired reproductive potential. (4) Absence of menarche by age 15 is statistically uncommon and should be evaluated. (5) Parameters for normal menstrual cyclicity indicate that most menstrual cycles for adolescents are between approximately 20 and 45 days. (6) Because menstrual cycles outside of this range are statistically uncommon, consideration should be give to evaluating adolescents with bleeding that is either too frequent or too infrequent. (7) A number of conditions with the potential for significant sequelae in adulthood can present as abnormal menses in adolescence, and thus merit early diagnosis and management.

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“…With anovulatory cycles and prolonged shedding of the endometrium, it is possible that even mild bleeding disorders lead to disproportionately heavy menstrual loss. Many present with acute adolescent menorrhagia requiring hospital admission and blood transfusion [17,18].…”

Section: Menstrual Problems In Women With Inherited Bleeding Disordersmentioning

confidence: 99%

The impact of menstrual disorders on quality of life in women with inherited bleeding disorders

2010

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Menorrhagia, heavy menstrual bleeding, is a common condition that has a substantial impact on the lives of many women. The objective measurement of menorrhagia is often impractical; therefore diagnosis and treatment are usually based on the direct perception of the woman. Menstrual problems are likely to be worse in women with bleeding disorders, as they are more likely to have heavy and painful menstrual periods and ovulation bleeding and pain. These can have a major impact on the quality of women's lives, especially those who suffer heavy menstruation. These problems can also lead to limitations at work and school and hinder educational and academic achievements. Only few studies describe how quality of life (QOL) changes in women with an underlying haemostatic defect; poorer QOL being associated with more frequent bleeding symptoms. Early recognition, accurate diagnosis and appropriate management of bleeding disorders should improve not only the quality of care for affected women but also their QOL. Increased awareness of the high prevalence of menstrual problems especially menorrhagia is essential for early diagnosis and provision of appropriate treatments without any delay. Accurate knowledge of the impact of menorrhagia on health-related quality of life (HRQOL) and its adequate assessment help individualize treatment and assess the magnitude of changes in HRQOL. An ideal situation would be to use a generic and a disease-specific measure together so that comparisons can be made on a general and disease-specific level.

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Acute Adolescent Menorrhagia

Cited by 14 publications

References 0 publications

Bleeding disorders in adolescents with menorrhagia: an institutional experience

Bleeding disorders in adolescents with menorrhagia: an institutional experience

Menstruation in Adolescents

The impact of menstrual disorders on quality of life in women with inherited bleeding disorders

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