2018
DOI: 10.1684/mst.2018.0819
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Acute descending necrotizing mediastinitis: four years of experience at a hospital center in Madagascar

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Cited by 7 publications
(9 citation statements)
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“…Acute mediastinitis can also occur in the context of cardio-thoracic surgery such as emergency interventions, prolonged operative or cardiopulmonary bypass time, bilateral internal mammary artery grafting, the complexity of procedures, the use of intra-aortic balloon pumps, lack of adequate antibiotic prophylaxis [10], as well as oesophageal perforations, and oropharyngeal infections such as para-pharyngeal abscess and odontoid process with epidural abscess of a descending necrotizing nature [11]. These triggering conditions are more aggressive if associated with factors such as age, smoking, chronic pulmonary disease, diabetes mellitus, chronic kidney failure, immunosuppression treatment with corticosteroids, and generalised atherosclerosis [12].…”
Section: Epidemiologymentioning
confidence: 99%
“…Acute mediastinitis can also occur in the context of cardio-thoracic surgery such as emergency interventions, prolonged operative or cardiopulmonary bypass time, bilateral internal mammary artery grafting, the complexity of procedures, the use of intra-aortic balloon pumps, lack of adequate antibiotic prophylaxis [10], as well as oesophageal perforations, and oropharyngeal infections such as para-pharyngeal abscess and odontoid process with epidural abscess of a descending necrotizing nature [11]. These triggering conditions are more aggressive if associated with factors such as age, smoking, chronic pulmonary disease, diabetes mellitus, chronic kidney failure, immunosuppression treatment with corticosteroids, and generalised atherosclerosis [12].…”
Section: Epidemiologymentioning
confidence: 99%
“…Otros autores señalan una relación más estrecha de tan solo 1,33 a 1, y una edad promedio de 30 años (26) . Lindenmann en 2013 (27) encontró que la perforación esofágica fue más frecuente en hombres (72%) que en mujeres (27%) y la edad promedio fue de 62 años. En este trabajo, la relación hombre:mujer fue de 3 a 1, y la edad promedio de 43 años, se encuentra en un rango intermedio a lo citado, probablemente porque la distribución según la etiología varíe según las series.La causa más frecuente de mediastinitis aguda fue la perforación esofágica.…”
Section: Discussionunclassified
“…Estos resultados son similares a la revisión de Wheatley (32) o los resultados de Makeieff (9) . Sin embargo, no concuerda con el trabajo de Lindenmann (27) , donde solo el 55% de los pacientes fueron sometidos a cirugía al diagnosticarse perforación esofágica, realizando tratamiento conservador en el 45% de los casos. En la serie reportada en este trabajo, sólo un paciente con perforación esofágica por cuerpo extraño no fue sometido a cirugía, con resolución del cuadro mediante extracción endoscópica y tratamiento antibiótico empírico.El promedio de intervenciones practicadas en esta serie es de 1,55 por paciente.…”
Section: Discussionunclassified
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“…6,[13][14][15] Of these, metabolic disorders such as diabetes mellitus or obesity, hepatic disorders, haematological disorders or the consumption of toxic agents have been most frequently incriminated. [13][14][15][16] In this current case, no immunosuppressive diseases leading to a decrease of the patient's immune response were identified. In contrast, the presence of purulent inflammatory infiltrate at the periphery of the septic necrotic areas demonstrates some reaction of the immune system, although this was unable to limit the extension of the infection.…”
Section: Discussionmentioning
confidence: 99%