Acute Effects of Tobacco Smoking on Hunger and Eating in Male and Female Smokers

Perkins, Kenneth A.; Sexton, Joan E.; DiMarco, Amy; Fonte, Carolyn

doi:10.1006/appe.1994.1014

Cited by 35 publications

(24 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…This study showed that chronic nicotine treatment with pair feeding has no significant effect on body weights and growth rate in non-pregnant female albino rats of the Wistar strain. This is consistent with the work of Perkins et al, 1994 reported no difference in total caloric intake or micronutrient or taste selection in smokers and non-smokers. Also the work of Winders and Grunberg (1993) showed that nicotine administration produce no comparable cumulative effect on growth rate even though he reported changes in food consumed and body weight.…”

Section: Resultssupporting

confidence: 93%

Effect Of Nicotine Administration On Weight And Histology Of Some Vital Visceral Organs In Female Albino Rats

Iranloye¹,

Bolarinwa²

2009

Nig. J. Phys Sci

View full text Add to dashboard Cite

Summary: It has been emphasized that cigarette smoking is not always synonymous with nicotine administration but the toxic effect of cigarette has often been associated with the nicotine content in cigarette. Epidemiologic studies have clearly indicated that cigarette smoking have many deleterious effects on visceral tissues in women. However it is not certain whether this effect is produced entirely by nicotine as cigarettes contain other toxic substances. Using an animal model the direct effect of nicotine administration on viscera tissues in female albino rats was investigated. Twenty-four female rats with regular oestrous cycle in the same phase of the cycle were divided into two equal groups with each group receiving 0.5mg/kg nicotine and 0.9% normal saline S.C. daily respectively. Six rats from each group were killed by cervical dissociation after 30 and 60 days treatment. The ovary, uterus, brain, kidney, heart, adrenal, pituitary and the liver were removed weighed and histological study carried out. Weights of the ovary, kidney, pituitary and uterus were significantly reduced (P< 0.05) following nicotine treatment while weights of the heart and liver increased with 60days treatment with the appearance of cartilaginous cells in the heart and deposition of adipose around the portal vein in the liver. Necrosis, congestion, fibrosis, follicular and endometrial degeneration were observed in the brain, pituitary, kidney, ovary and uterus respectively. No significant difference between the weekly growth rates in nicotine treated (5.13 ± .29) and control (5.25 ± 0.18) animals. Nicotine has deleterious effects on some vital visceral organs with observations similar to those reported in women smokers.

show abstract

Section: Resultssupporting

confidence: 93%

Effect Of Nicotine Administration On Weight And Histology Of Some Vital Visceral Organs In Female Albino Rats

Iranloye¹,

Bolarinwa²

2009

Nig. J. Phys Sci

View full text Add to dashboard Cite

show abstract

“…The control cigarettes were not expected to deliver a psychoactive dose of nicotine. Prior studies have demonstrated that the boost in plasma concentrations of nicotine delivered with a smokeless cigarette (0.13 mg nicotine) was approximately 1.0 ng/ml , while the boost in plasma concentrations after smoking a 0.2 mg cigarette was 4.5 ng/ml and the total plasma concentration after smoking five 0.10 mg cigarettes was only 11 ng/ml (Perkins et al 1994a). Thus, each control cigarette in this study was expected to boost the plasma concentration of nicotine by approximately 2.5 ng/ml.…”

Section: Methodsmentioning

confidence: 96%

The effects of smoking high nicotine cigarettes on prepulse inhibition, startle latency, and subjective responses

2000

View full text Add to dashboard Cite

show abstract

“…A maioria dos estudos mostra que o uso da nicotina produz período de perda de peso (ou redução do ganho de peso), assim como a cessação do uso da droga é seguida de período agudo de ganho de peso, com recuperação e equiparação ao peso observado nos animais controle. São três as teorias mais aceitas para explicar a relação do tabagismo e do peso corporal: aumento da taxa metabólica, com maior gasto de energia pelos fumantes 8,9 ; diferenças na qualidade e quantidade dos alimentos ingeridos pelos fumantes 10,11 e ação anorética da nicotina 12,13 . Os mecanismos fisiopatológicos que levam ao retardo de crescimento intra-uterino em fetos de mães fumantes não estão totalmente elucidados 14,15 .…”

unclassified

Influência da exposição a fumaça lateral do cigarro sobre o ganho de peso e o consumo alimentar de ratas gestantes: análise do peso e do comprimento dos filhotes ao nascimento

Mello¹,

Okay²,

Botelho³

2006

Rev. Bras. Ginecol. Obstet.

View full text Add to dashboard Cite

RESUMOObjetivos: analisar o efeito do tabagismo sobre o ganho ponderal e o consumo alimentar de ratas durante a gestação, e o peso e comprimento dos filhotes ao nascimento. Métodos: foram estudadas 51 ratas (Wistar) do 2º dia até o final da gestação, divididas em três grupos: Grupo F: 15 ratas expostas à fumaça de dois cigarros/animal/dia + ar comprimido (10 L/ min); Grupo Ar: 18 ratas expostas ao ar comprimido (10 L/min); Grupo C: 18 ratas não manipuladas e não expostas. Os parâmetros aferidos foram: peso das ratas e seu consumo alimentar e comprimento e peso dos filhotes ao nascer. Foi aplicado o teste de Lavene para verificação do comportamento da distribuição das variáveis numéricas, e para análises paramétricas utilizou-se o ANOVA ou teste t de Student, conforme o caso. O nível de significância adotado foi p<0,05. Resultados: as ratas expostas ao tabaco consumiram menos alimentos por dia [Grupo F=18,9 (±1,2) vs Grupo Ar=21,7 (±1,6) vs Grupo C=24,2 (±1,7); (p<0,05)] e apresentaram menor ganho ponderal ao final da gestação em relação às ratas expostas ao ar comprimido e ao grupo controle: peso no vigésimo dia de gestação: Grupo F=338,9 g (±13,8) vs Grupo Ar=352,3g (±15,9) vs Grupo C=366,3 g (±13,1); p<0,001). O peso dos filhotes ao nascimento [(Grupo F=5,5 g (±0,3); Grupo Ar=5,9 g (±0,5); Grupo C=5,9 g (±0,4) -p<0,01] e o comprimento ao nascer [Grupo F=6,8 cm (±0,2); Grupo Ar=6,9 cm (±0,2); Grupo C=6,9 cm (±0,1) -p<0,05] foram significativamente menores no grupo de ratas expostas ao tabaco em relação aos outros dois grupos, que não diferiram entre si. Conclusões: a exposição ao tabaco reduziu o ganho ponderal e o consumo alimentar das ratas durante a gestação e produziu redução do peso e do comprimento dos filhotes ao nascimento. PALAVRAS-CHAVE:Tabagismo; Gestação; Ganho de peso; Peso ao nascer; Retardo do crescimento fetal; Ratos ABSTRACT Purpose: to analyze the effect of cigarette smoke on weight gain and food consumption of female pregnant rats, as well as of their offspring's weight and length at birth Methods: Wistar rats were studied from the second day until the end of pregnancy. Fifty-one female rats were divided into three groups: Group F: 15 rats exposed to tobacco smoke (2 cigarettes/animal/day) plus air flush (10 L/min); Group Air: 18 rats exposed to air flush only (10 L/min); Group C: 18 non-exposed, non-manipulated controls. Body weight was measured every 5 days and food consumption every seven days (expressed as medium consumption per day). Offspring weight and length were measured on the first day of life. The Lavene test was used to verify the behavior of numeric variable distribution and for parametric one-way ANOVA analysis and Student's t test were used, according to the case. Results with p<0.05 were considered to be statistically significant. Results: the rats of Group F consumed less food per day [Group F=18.9 g (±1.2) vs Group Air=21.7 g (±1,6) vs Group C=24.2g (±1,7); (p<0,05)], gained less weight during pregnancy than the animals of the air flush group and the control group: Group F=...

show abstract

Acute Effects of Tobacco Smoking on Hunger and Eating in Male and Female Smokers

Cited by 35 publications

References 0 publications

Effect Of Nicotine Administration On Weight And Histology Of Some Vital Visceral Organs In Female Albino Rats

Effect Of Nicotine Administration On Weight And Histology Of Some Vital Visceral Organs In Female Albino Rats

The effects of smoking high nicotine cigarettes on prepulse inhibition, startle latency, and subjective responses

Influência da exposição a fumaça lateral do cigarro sobre o ganho de peso e o consumo alimentar de ratas gestantes: análise do peso e do comprimento dos filhotes ao nascimento

Contact Info

Product

Resources

About