Acute genitourinary toxicity after high-dose-rate (HDR) brachytherapy combined with hypofractionated external-beam radiation therapy for localized prostate cancer: Correlation between the urethral dose in HDR brachytherapy and the severity of acute genitourinary toxicity

A comparison of inverse optimization algorithms for HDR/PDR prostate brachytherapy treatment planning

“…The use of less needles might be beneficial in terms of implantation time, cost, and possibly reduce traumarelated morbidity (43). On the other hand, using a very limited amount of catheters is associated with a high urethral dose and can lead to increased acute urinary toxicity (44). In addition, the use of more catheters improves homogeneity and conformity of the dose distribution (38).…”

Health-Related Quality of Life After Single-Fraction High-Dose-Rate Brachytherapy and Hypofractionated External Beam Radiotherapy for Prostate Cancer

“…In cases in which multiple HDR-BT implants have been performed, it is not usually possible to determine a composite dose-volume histogram of the total treatment. Akimoto et al (25) reported an association between the urethral dose and acute urinary toxicity, with a range of HDR-BT doses of 5 Gy  5 to 9 Gy  2. Ghadjar et al (26) also noted a borderline association between the urethral V 120 and late urinary toxicity using a HDR-BT dose of 7 Gy  3.…”

Dosimetric Evaluation of High-Dose-Rate Interstitial Brachytherapy Boost Treatments for Localized Prostate Cancer

“…Akimoto [1] 70 --V30(u), V80(u), V90(u), V100(u), V110(u), V120(u), V130(u), V150(u) Akimoto [2] 67 --D5(u), D10(u), D20(u), D50(u) Baltas [4] 40 -COIN -Bölling [5] 53 V100, V150, V200, D90, D100 -D max (r), D 2ccm (r), D min (u), D max (u), D1(u) Charra-Brunaud [6] 24 V150 COIN, HI V150(u)…”