Acute kidney injury in Lagos: Pattern, outcomes, and predictors of in-hospital mortality

Bello, Babawale Taslim; Busari, AA; Amira, Christiana Oluwatoyin; Raji, YR; Rw, Braimoh

doi:10.4103/1119-3077.183258

Cited by 12 publications

(14 citation statements)

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“…However, more studies with a large national representative sample are urgently required. The mortality rate of AKI in the present study falls below the range quoted in the literature as 16 to 63.3% [21]. The likely explanation is the small sample size of this study.…”

Section: Discussioncontrasting

confidence: 81%

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Frequency, Epidemiology and Outcome of Acute Kidney Injury Among Patients Admitted to Nephrology Center, Sana’a: Observational Study

Abuasba¹,

Alwadee²,

Al-Hamadi³

2018

AJIM

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Although acute kidney injury (AKI) in our setting is growing rapidly, the available data on the magnitude of this lethal problem are very limited. The objective of this study was to determine the incidence, epidemiology and outcome of AKI. A total of 143 hospitalized patients with AKI in Al Thawra General Hospital, nephrology department between July 2015 and December 2016 were enrolled. The mean age of the study population was 37.7 ± 8.4 years, and 68.5% of these patients were males. Almost 81.8% of cases were medically referred and malarial infection was the commonest cause of AKI (23%). Pre renal AKI was present in 65 patients (45.4%) and renal AKI in 78 patients (54.5%). Most cases were presented with clinical manifestation of volume overload (65%), oliguria (51.7%), anuria (16.7%), and high serum creatinine level. The majority of cases (58.7%) had recovered without dialysis. In-hospital mortality was observed in 11 patients (7.7%). Hepatic failure and malarial infection were the common causes of death. This study demonstrates low frequency of AKI in our setting. The etiologies of this lethal health problem are preventable and treatable in approximately half of cases. Late referral to hospital may contribute both to the progression of renal disease and also to high mortality.

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Section: Discussioncontrasting

confidence: 81%

“…It is reported in one study that in-hospital mortality rate of AKI was 29.6% [21]. Brown JR et al [8] in a study carried out in the USA from 2001 to 2011 found that the in-hospital mortality associated with AKI has been on the decline starting from 21.9% in 2001to 9.1% in 2011.…”

Section: Discussionmentioning

confidence: 97%

Frequency, Epidemiology and Outcome of Acute Kidney Injury Among Patients Admitted to Nephrology Center, Sana’a: Observational Study

Abuasba¹,

Alwadee²,

Al-Hamadi³

2018

AJIM

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“…Estudos constataram que complicações provenientes da gravidez são responsáveis por 16% dos casos de IRA, tais como: aborto séptico, eclampsia e hemorragia pós-parto (Halle et al, 2017;Bello, Busari, Amira, Raji & Braimoh, 2017).…”

Section: Discussionunclassified

“…Classifica-se a necrose tubular aguda como isquêmica e nefrotóxica, tendo como principal meio de diagnóstico o exame clínico, ultrassonografia e exames laboratoriais. Associando-se frequentemente a fatores extrínsecos tais como os agentes potencialmente nefrotóxicos, hipoperfusão ou hipovolemia; caracteriza-se por ser responsável por 33,2% de complicações renais graves (Bello et al, 2017;Bragato, Fioravanti, Braga, Reis & Borges, 2015).…”

Section: Discussionunclassified

Fatores de risco para Lesão Renal Aguda em Unidade de Terapia Intensiva

Dantas

Vieira

Oliveira

et al. 2021

RSD

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Objetivo: avaliar as condições clínicas e intervenções terapêuticas que predispõem a ocorrência da IRA nos pacientes internados em UTI. Método: trata-se de uma Revisão Sistemática da Literatura nas seguintes fontes de dados: PUBMED, MEDLINE, LILACS, BDENF e SCIELO. As evidências dos estudos foram classificadas conforme (XX). Foram utilizados os seguintes descritores: “Hemodiálise” AND “Terapia intensiva”. Resultados: destaca-se que a IRA na UTI está relacionada à: fatores de risco associados à terapêutica (uso de DVA, VMI, antibioticoterapia, nefropatia medicamentosa e induzida pelo uso de contraste à base de iodo); comorbidades (DM, HAS, pulmonares, digestivas, hepáticas, neoplasias, anemia, obesidade e imunossupressão), agravos agudos (trauma, hemorragia, acidente ofídico, choque, infecção, sepse, eclâmpsia; complicações de doença cardiovascular, de doença neurológica aguda, necrose tubular aguda, síndrome hepatorenal e acidentes com animais peçonhentos), idade, distúrbios hidroeletrolíticos (hipercalcêmia, hipocalcêmia, hipernatremia e a hiponatremia), distúrbios do equilíbrio ácido básico, balanço hídrico acumulativo e necrose tubular aguda. Conclusão: constata-se que a IRA na UTI tem relaciona-se com a condição clínica do paciente e intervenções terapêuticas realizadas na UTI.

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“…Además, la morbilidad y la mortalidad por esta causa se han mantenido relativamente altas durante las últimas seis décadas [8]. Las diferencias observadas entre países desarrollados y en vía de desarrollo en el patrón epidemiológico de LRA incluyen los individuos afectados, su etiología, el entorno en el que ocurre y las modalidades de terapia de reemplazo renal (TRR) disponibles y sus resultados [9,10].…”

Section: Epidemiologíaunclassified

Lesión renal aguda en la mujer embarazada

Robles¹,

Rico-Fontalvo

Daza-Arnedo

et al. 2020

Rev. Colomb. Nefrol.

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Aunque en la actualidad la lesión renal aguda en mujeres embarazadas es una complicación poco común, esta se correlaciona con peores desenlaces maternos y fetales. Sus causas son múltiples y varían según el trimestre de presentación. Los cambios fisiológicos renales durante el embarazo hacen que los criterios diagnósticos de lesión renal aguda en la población general no sean fácilmente extrapolables a las pacientes obstétricas, por lo que la sospecha temprana y eltratamiento oportuno son fundamentales para evitar la progresión del daño renal y sus complicaciones sistémicas asociadas, incluidas las metabólicas, urémicas e hidroelectrolíticas.

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Acute kidney injury in Lagos: Pattern, outcomes, and predictors of in-hospital mortality

Abstract: The pattern of AKI in this study is similar to that from other developing countries. In-hospital mortality remains high although most of the causes are preventable.

Cited by 12 publications

References 0 publications

Frequency, Epidemiology and Outcome of Acute Kidney Injury Among Patients Admitted to Nephrology Center, Sana’a: Observational Study

Frequency, Epidemiology and Outcome of Acute Kidney Injury Among Patients Admitted to Nephrology Center, Sana’a: Observational Study

Fatores de risco para Lesão Renal Aguda em Unidade de Terapia Intensiva

Lesión renal aguda en la mujer embarazada

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