2020
DOI: 10.1016/j.jcot.2020.06.017
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Acute normovolemic hemodilution in major orthopedic surgery

Abstract: Background: With increasing concerns regarding the newer emerging pathogens, alternatives to allogeneic blood transfusion are being explored and acute normovolemic hemodilution (ANH) is one of them. Methods: A prospective study was conducted in patients aged 18e65 years with preoperative hemoglobin >12 g/dl undergoing total knee replacement or total hip replacement. Patients in whom hemodilution was performed were included in the ANH group whereas patients undergoing treatment as per the routine hospital proto… Show more

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Cited by 12 publications
(12 citation statements)
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“…This might be associated with the less loss of red blood cell mass during surgery and the return of fresh platelets and clotting factors at the end of surgery. This result is consistent with most of the previous studies [ 25 28 ]. Moreover, intraoperative transfusion amount, allogenic transfusion, and postoperative transfusion amount of patients treated by TXA combined ANH were statistically lower than that in patients treated by ANH or TXA alone, respectively.…”
Section: Discussionsupporting
confidence: 94%
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“…This might be associated with the less loss of red blood cell mass during surgery and the return of fresh platelets and clotting factors at the end of surgery. This result is consistent with most of the previous studies [ 25 28 ]. Moreover, intraoperative transfusion amount, allogenic transfusion, and postoperative transfusion amount of patients treated by TXA combined ANH were statistically lower than that in patients treated by ANH or TXA alone, respectively.…”
Section: Discussionsupporting
confidence: 94%
“…The hemoglobin and PCV at the postoperative first day was significantly higher in ANH group than that in control group. This can be attributed to the improved blood microcirculation of ANH [ 24 , 25 ]. In addition, the autologous blood in ANH group preserves the platelet function and thus provides platelets and clotting factors after returning back to body [ 25 ].…”
Section: Discussionmentioning
confidence: 99%
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“…This technique has been well demonstrated in a variety of surgeries including total knee and hip replacements to reduce blood transfusion requirements. 69,70…”
Section: Pre-incision Preparationmentioning
confidence: 99%
“…Этот метод приобрел популярность в 1990-х гг., особенно при операциях по коррекции сколиотической деформации позвоночника у детей [15]. Однако ввиду простоты выполнения, контролируемости процедуры она актуальна и применяется при разнообразных операциях, связанных с повышенной травматичностью и значительной кровопотерей [21][22][23]. Интраоперационная реинфузия крови -это технология, при которой излившаяся в рану кровь собирается, фильтруется, отмывается и возвращается пациенту.…”
Section: прогнозирование интраоперационной кровопотери и методы ее ог...unclassified